6-methoxypyridine-2-carbonitrile
- CAS No.
- 83621-01-6
- Chemical Name:
- 6-methoxypyridine-2-carbonitrile
- Synonyms
- 6-methoxypicolinonitrile;133750;2-Cyano-6-methoxypyridine;6-Methoxy-2-Pyridinecarbonitrile;2-Pyridinecarbonitrile,6-methoxy-;6-Methoxy-2-pyridinecarbonitrile 97%
- CBNumber:
- CB51094166
- Molecular Formula:
- C7H6N2O
- Molecular Weight:
- 134.14
- MDL Number:
- MFCD08062856
- MOL File:
- 83621-01-6.mol
- MSDS File:
- SDS
| Melting point | 62-67°C |
|---|---|
| Boiling point | 115-120 °C(Press: 19 Torr) |
| Density | 1.16±0.1 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| form | solid |
| pka | -2.15±0.10(Predicted) |
| Appearance | White to off-white Solid |
| InChI | 1S/C7H6N2O/c1-10-7-4-2-3-6(5-8)9-7/h2-4H,1H3 |
| InChIKey | LTSUUWWSGRKYFO-UHFFFAOYSA-N |
| SMILES | COc1cccc(n1)C#N |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301-H312-H315-H318-H332-H335 |
| Precautionary statements | P261-P280-P301+P310-P305+P351+P338 |
| target organs | Respiratory system |
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22-37/38-41 |
| Safety Statements | 26-36/37/39 |
| RIDADR | UN 3439 6.1 / PGIII |
| WGK Germany | 3 |
| HS Code | 2933399990 |
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
| Hazard Classifications | Acute Tox. 3 Oral Eye Dam. 1 Skin Irrit. 2 STOT SE 3 |
6-methoxypyridine-2-carbonitrile price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR901728 | 6-Methoxypyridine-2-carbonitrile 97% | 83621-01-6 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR901728 | 6-Methoxypyridine-2-carbonitrile 97% | 83621-01-6 | 5g | $100 | 2026-06-04 | Buy |
| Apolloscientific | OR901728 | 6-Methoxypyridine-2-carbonitrile 97% | 83621-01-6 | 25g | $470 | 2026-06-04 | Buy |
| Apolloscientific | OR901728 | 6-Methoxypyridine-2-carbonitrile 97% | 83621-01-6 | 100g | $1789 | 2026-06-04 | Buy |
| Activate Scientific | AS48425 | 6-Methoxypyridine-2-carbonitrile 98% | 83621-01-6 | 1g | $35 | 2026-06-04 | Buy |
6-methoxypyridine-2-carbonitrile Chemical Properties, Uses, Production
Synthesis
98276-69-8
83621-01-6
GENERAL STEPS: To a solution of 6-methoxypyridine-2-carboxamide (300 mg, 1.97 mmol) in tetrahydrofuran (THF, 3 mL) was added triethylamine (1.25 mL, 8.68 mmol), followed by the slow dropwise addition of trifluoroacetic anhydride (TFAA, 0.61 mL, 4.34 mmol), under ice-bath conditions. The reaction mixture was gradually warmed to room temperature and stirred overnight. Upon completion of the reaction, the volatile solvent was removed by distillation under reduced pressure and the remaining liquid residue was slowly added dropwise to vigorously stirred, ice-cold pH 7 phosphate buffer solution (5 mL). After continued stirring for 15 min, the resulting pale yellow solid was collected by filtration and dried in air for 1 h. 6-Methoxypyridine-2-carbonitrile (250 mg, 95% yield) was obtained as a pale yellow solid with a mass spectrum (m/z): 135.4 [M + 1]+.
References
[1] Patent: WO2009/70485, 2009, A1. Location in patent: Page/Page column 105
6-methoxypyridine-2-carbonitrile Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| PharmaBlock Sciences (Nanjing),Inc. | 025-86918202 4000255188 | sales@pharmablock.com | China | 5000 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shanghai Sinch Parmaceuticals Tech. Co. Ltd. | +86-21-54098501 | sales@sinch.com.cn | China | 11592 | 64 |
| ZEROSCHEM.CO.,LTD. | 10-61256048 13810278579; | sales@zeroschem.com | China | 1400 | 59 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| ChemShuttle, Inc. | 0510-83588313-811 18800520310 | sales@chemshuttle.com | China | 2999 | 62 |
| ShangHai YuanYe Biotechnology Co., Ltd. | 15026964105 | shyysw007@163.com | China | 4998 | 60 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Jinan LuoHe PharmaTech Co., Ltd. | 86-0531-68658065 15726150375 | 1071018499@qq.com | China | 525 | 58 |
| ShangHai Yuchuan Pharmaceutical Technology Co., Ltd. | 02161555100 | China | 820 | 58 |
View Latest Price from 6-methoxypyridine-2-carbonitrile manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-02-05 | 6-Methoxypyridine-2-carbonitrile
83621-01-6
|
$1.00 | 1KG | Min98% HPLC | Career Henan Chemical Co |
-
- 6-Methoxypyridine-2-carbonitrile
83621-01-6
- $1.00
- Min98% HPLC
- Career Henan Chemical Co
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