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6-methoxypyridine-2-carbonitrile

CAS No.
83621-01-6
Chemical Name:
6-methoxypyridine-2-carbonitrile
Synonyms
6-methoxypicolinonitrile;133750;2-Cyano-6-methoxypyridine;6-Methoxy-2-Pyridinecarbonitrile;2-Pyridinecarbonitrile,6-methoxy-;6-Methoxy-2-pyridinecarbonitrile 97%
CBNumber:
CB51094166
Molecular Formula:
C7H6N2O
Molecular Weight:
134.14
MDL Number:
MFCD08062856
MOL File:
83621-01-6.mol
MSDS File:
SDS
Last updated:2026-05-28 01:57:00
Product description Number Pack Size Price
6-Methoxypyridine-2-carbonitrile 97% OR901728 1g $21
6-Methoxypyridine-2-carbonitrile 97% OR901728 5g $100
6-Methoxypyridine-2-carbonitrile 97% OR901728 25g $470
6-Methoxypyridine-2-carbonitrile 97% OR901728 100g $1789
6-Methoxypyridine-2-carbonitrile 97% OR901728 1g $21
More product size

6-methoxypyridine-2-carbonitrile Properties

Melting point 62-67°C
Boiling point 115-120 °C(Press: 19 Torr)
Density 1.16±0.1 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
form solid
pka -2.15±0.10(Predicted)
Appearance White to off-white Solid
InChI 1S/C7H6N2O/c1-10-7-4-2-3-6(5-8)9-7/h2-4H,1H3
InChIKey LTSUUWWSGRKYFO-UHFFFAOYSA-N
SMILES COc1cccc(n1)C#N
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Skull and Crossbones (GHS06)
GHS05,GHS06
Signal word  Danger
Hazard statements  H301-H312-H315-H318-H332-H335
Precautionary statements  P261-P280-P301+P310-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes  Xn
Risk Statements  20/21/22-37/38-41
Safety Statements  26-36/37/39
RIDADR  UN 3439 6.1 / PGIII
WGK Germany  3
HS Code  2933399990
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Oral
Eye Dam. 1
Skin Irrit. 2
STOT SE 3

6-methoxypyridine-2-carbonitrile price More Price(54)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR901728 6-Methoxypyridine-2-carbonitrile 97% 83621-01-6 1g $21 2026-06-04 Buy
Apolloscientific OR901728 6-Methoxypyridine-2-carbonitrile 97% 83621-01-6 5g $100 2026-06-04 Buy
Apolloscientific OR901728 6-Methoxypyridine-2-carbonitrile 97% 83621-01-6 25g $470 2026-06-04 Buy
Apolloscientific OR901728 6-Methoxypyridine-2-carbonitrile 97% 83621-01-6 100g $1789 2026-06-04 Buy
Apolloscientific OR901728 6-Methoxypyridine-2-carbonitrile 97% 83621-01-6 1g $21 2026-06-04 Buy
Product number Packaging Price Buy
OR901728 1g $21 Buy
OR901728 5g $100 Buy
OR901728 25g $470 Buy
OR901728 100g $1789 Buy
OR901728 1g $21 Buy

6-methoxypyridine-2-carbonitrile Chemical Properties,Uses,Production

Synthesis

6-METHOXY-PYRIDINE-2-CARBOXYLIC ACID AMIDE

98276-69-8

6-methoxypyridine-2-carbonitrile

83621-01-6

GENERAL STEPS: To a solution of 6-methoxypyridine-2-carboxamide (300 mg, 1.97 mmol) in tetrahydrofuran (THF, 3 mL) was added triethylamine (1.25 mL, 8.68 mmol), followed by the slow dropwise addition of trifluoroacetic anhydride (TFAA, 0.61 mL, 4.34 mmol), under ice-bath conditions. The reaction mixture was gradually warmed to room temperature and stirred overnight. Upon completion of the reaction, the volatile solvent was removed by distillation under reduced pressure and the remaining liquid residue was slowly added dropwise to vigorously stirred, ice-cold pH 7 phosphate buffer solution (5 mL). After continued stirring for 15 min, the resulting pale yellow solid was collected by filtration and dried in air for 1 h. 6-Methoxypyridine-2-carbonitrile (250 mg, 95% yield) was obtained as a pale yellow solid with a mass spectrum (m/z): 135.4 [M + 1]+.

References

[1] Patent: WO2009/70485, 2009, A1. Location in patent: Page/Page column 105

6-methoxypyridine-2-carbonitrile Preparation Products And Raw materials

Global( 67)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29792 58
Hefei Hirisun Pharmatech Co., Ltd
+8615056975894 shawn@hirisunpharm.com CHINA 9911 58
Dayang Chem (Hangzhou) Co.,Ltd.
+86-0571-88938639 +8617705817739 info@dycnchem.com China 52704 58
PT CHEM GROUP LIMITED
+86-85511178; peter68@ptchemgroup.com China 35425 58
HANGZHOU LEAP CHEM CO., LTD.
+86-571-87711850 market18@leapchem.com China 43333 58
Aladdin Scientific
tp@aladdinsci.com United States 57505 58
Suzhou ARTK Medchem Co., Ltd.
+8618118463618 sales1@artkmedchem.com China 39021 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 131956 58

View Lastest Price from 6-methoxypyridine-2-carbonitrile manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
6-Methoxypyridine-2-carbonitrile pictures 2020-02-05 6-Methoxypyridine-2-carbonitrile
83621-01-6
$1.00 1KG Min98% HPLC Career Henan Chemical Co

6-methoxypyridine-2-carbonitrile Spectrum

2-Cyano-6-methoxypyridine 6-Methoxy-2-pyridinecarbonitrile 97% 2-Pyridinecarbonitrile,6-methoxy- 6-Methoxy-2-Pyridinecarbonitrile 133750 6-methoxypicolinonitrile 83621-01-6