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Ethyl 5-amino-4-phenylisoxazole-3-carboxylate

Ethyl 5-amino-4-phenylisoxazole-3-carboxylate structure

CAS No.: 53983-15-6

Chemical Name:: Ethyl 5-amino-4-phenylisoxazole-3-carboxylate

Synonyms: Ethyl 5-amino-4-phenyl-3-isoxazolecarboxylate;ethyl 5-amino-4-phenyl-1,2-oxazole-3-carboxylate;5-amino-4-phenyl-3-Isoxazolecarboxylic acid ethyl ester;3-Isoxazolecarboxylic acid, 5-amino-4-phenyl-, ethyl ester

CBNumber:: CB51116574

Molecular Formula:: C12H12N2O3

Molecular Weight:: 232.24

MDL Number:: MFCD06199347

MOL File:: 53983-15-6.mol

Last updated:2026-05-28 02:10:59

Request For Quotation

Ethyl 5-amino-4-phenylisoxazole-3-carboxylate Properties

storage temp.	2-8°C(protect from light)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

Ethyl 5-amino-4-phenylisoxazole-3-carboxylate price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth	DCA98315	ethyl 5-amino-4-phenyl-1,2-oxazole-3-carboxylate	53983-15-6	2.5g	$413	2026-06-04	Buy
Matrix Scientific	301076	Ethyl 5-amino-4-phenylisoxazole-3-carboxylate	53983-15-6	250.00mg	$49	2026-05-19	Buy
Matrix Scientific	301076	Ethyl 5-amino-4-phenylisoxazole-3-carboxylate	53983-15-6	1.00g	$99	2026-05-19	Buy
Matrix Scientific	301076	Ethyl 5-amino-4-phenylisoxazole-3-carboxylate	53983-15-6	5.00g	$343	2026-05-19	Buy
Synthonix	E55720	Ethyl 5-amino-4-phenylisoxazole-3-carboxylate 97%	53983-15-6	250mg	$120	2026-05-06	Buy

Product number	Packaging	Price	Buy
DCA98315	2.5g	$413	Buy
301076	250.00mg	$49	Buy
301076	1.00g	$99	Buy
301076	5.00g	$343	Buy
E55720	250mg	$120	Buy

Ethyl 5-amino-4-phenylisoxazole-3-carboxylate Chemical Properties,Uses,Production

Synthesis

Benzenepropanoic acid, β-methyl-, ethyl ester, (βS)-

1134-71-0

53983-15-6

General procedure for the synthesis of ethyl 5-amino-4-phenylisoxazole-3-carboxylate from the compound (CAS: 1134-71-0): phenylpropyl derivative 1 (12 mmol), hydroxylamine hydrochloride (1.66 g, 24 mmol) and 70 mL of ethanol were mixed and heated and refluxed for 12 hours. Upon completion of the reaction, the ethanol was removed by distillation under reduced pressure. Subsequently, 50 mL of ethyl acetate and 10 mL of 10% sodium carbonate solution were added to the residue and mixed thoroughly to separate the organic phase. The organic phase was washed with saturated sodium chloride solution and dried with anhydrous sodium sulfate. Finally, the ethyl acetate was removed by evaporation under reduced pressure to give 2.48 g of white powdery solid product in 89.11% yield.

References

[1] Patent: CN105777661, 2016, A. Location in patent: Paragraph 0041; 0042; 0043

Ethyl 5-amino-4-phenylisoxazole-3-carboxylate Preparation Products And Raw materials

Raw materials

alpha-Methylphenylacetonitrile Benzenepropanoic acid, β-methyl-, ethyl ester, (βS)- Ethanol Hydroxylamine hydrochloride

Preparation Products

Ethyl 5-amino-4-phenylisoxazole-3-carboxylate Suppliers

Global( 21)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
HBCChem, Inc.	+1-510-219-6317	sales@hbcchem.com	United States	10628	60
Cool Pharm, Ltd	021-60455363 18019463053	sales@coolpharm.com	China	8455	58
Zhengzhou Guancheng Laboratory equipment Sales	0371-88888888 qq272369594;2159423853qq	2723695949@qq.com	China	4991	50
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58
Energy Chemical	021-58432009 400-005-6266	marketing@energy-chemical.com	China	44871	58
Jiangsu Nanchuang Chemical and Life Health Research Institute Co., Ltd.	15720605021	zhang_lei@jsnchem.com	China	1881	58
Beijing Stronger Science Co., Ltd.	0531-88924771 15614660963	elsa.hang@strongerscience.com	China	10622	58
Bide Pharmatech Ltd.	400-1647117 13681763483	product02@bidepharm.com	China	59929	58
Bide Pharmatech Ltd.	400-6005915	sales@picasso-e.com	China	39645	58
Zhengzhou Converging Chemical Co. LTD	0371-53399770 18037166334	3857571523@qq.com	China	7099	58

Supplier	Advantage
HBCChem, Inc.	60
Cool Pharm, Ltd	58
Zhengzhou Guancheng Laboratory equipment Sales	50
Amadis Chemical Company Limited	58
Energy Chemical	58
Jiangsu Nanchuang Chemical and Life Health Research Institute Co., Ltd.	58
Beijing Stronger Science Co., Ltd.	58
Bide Pharmatech Ltd.	58
Bide Pharmatech Ltd.	58
Zhengzhou Converging Chemical Co. LTD	58

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5-amino-4-phenyl-3-Isoxazolecarboxylic acid ethyl ester 3-Isoxazolecarboxylic acid, 5-amino-4-phenyl-, ethyl ester Ethyl 5-amino-4-phenyl-3-isoxazolecarboxylate ethyl 5-amino-4-phenyl-1,2-oxazole-3-carboxylate 53983-15-6