Nitracrine
- CAS No.
- 4533-39-5
- Chemical Name:
- Nitracrine
- Synonyms
- Nitracrine;3-(dimethylamino)propyl-(1-nitroacridin-9-yl)amine;N',N'-dimethyl-N-(1-nitroacridin-9-yl)propane-1,3-diamine;1,3-Propanediamine, N1,N1-dimethyl-N3-(1-nitro-9-acridinyl)-
- CBNumber:
- CB51179326
- Molecular Formula:
- C18H20N4O2
- Molecular Weight:
- 324.382
- MDL Number:
- MFCD00866469
- MOL File:
- 4533-39-5.mol
- MSDS File:
- SDS
| Melting point | 134-135° |
|---|---|
| Boiling point | 462.71°C (rough estimate) |
| Density | 1.2155 (rough estimate) |
| refractive index | 1.6700 (estimate) |
| storage temp. | Store at -20°C |
| solubility | Soluble in DMSO |
| form | Solid |
| pka | pKa1 6.45; pKa2 8.8(at 25℃) |
| color | Brown to reddish brown |
| FDA UNII | 712MLZ30SB |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
Nitracrine price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | EAA53339 | Nitracrine | 4533-39-5 | 1mg | $1227.91 | 2026-06-04 | Buy |
| Biosynth | EAA53339 | Nitracrine | 4533-39-5 | 5mg | $3990.7 | 2026-06-04 | Buy |
| Biosynth | EAA53339 | Nitracrine | 4533-39-5 | 10mg | $6385.1 | 2026-06-04 | Buy |
| Biosynth | EAA53339 | Nitracrine | 4533-39-5 | 25mg | $11972 | 2026-06-04 | Buy |
| Biosynth | EAA53339 | Nitracrine | 4533-39-5 | 50mg | $19155.5 | 2026-06-04 | Buy |
Nitracrine Chemical Properties, Uses, Production
Uses
Nitracrine inhibits RNA synthesis and covalently, reversibly binds to DNA but also forms covalent adducts with DNA in vivo. Nitracrine, a 1-nitroacridine derivative, is a potent hypoxia-selective agent in vitro and antitumor agent. Nitracrine has cytotoxicity towards most cells[1][2][3].
Definition
ChEBI: Nitracrine is a member of acridines.
References
[1] Wilson WR, et al. Selective toxicity of nitracrine to hypoxic mammalian cells. Br J Cancer. 1984 Feb;49(2):215-23. DOI:10.1038/bjc.1984.34
[2] Gniazdowski M, et al. Nitracrine and its congeners--an overview. Gen Pharmacol. 1995 May;26(3):473-81. DOI:10.1016/0306-3623(94)00143-b
[3] Daghastanli NA, et al. Cytotoxicity of nitroheterocyclic compounds, quinifuryl and nitracrine, towards leukaemic and normal cells on the dark and under illumination with visible light. J Photochem Photobiol B. 2004 Jul 19;75(1-2):27-32. DOI:10.1016/j.jphotobiol.2004.04.005
Nitracrine Preparation Products And Raw materials
Raw materials
Preparation Products
Nitracrine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| LGM Pharma | 1-(800)-881-8210 | inquiries@lgmpharma.com | United States | 2110 | 70 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4853 | 58 |
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4773 | 55 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shenzhen Regent Biochemical Technology Co., Ltd. | 0755-85201366 18938635012 | sales@regentsciences.com | China | 9384 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| Suzhou Chenrui Biotechnology Co. LTD | 17625585511 | 1580084073@qq.com | China | 990 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 | psaitong@jm-bio.com | China | 27626 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
View Latest Price from Nitracrine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-21 | Nitracrine
4533-39-5
|
$1520.00-2500.00 | 10g | TargetMol Chemicals Inc. |
-
- Nitracrine
4533-39-5
- $1520.00-2500.00
- TargetMol Chemicals Inc.
