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2-Bromo-5-chlorophenol

CAS No.
13659-23-9
Chemical Name:
2-Bromo-5-chlorophenol
Synonyms
2-Bromo-5-chlorophen;Phenol,2-broMo-5-chloro-;2-Bromo-5-chlorophenol 98%;2-Bromo-5-chlorophenol, 98%;4-Chloro-2-hydroxybromobenzene
CBNumber:
CB51180371
Molecular Formula:
C6H4BrClO
Molecular Weight:
207.45
MDL Number:
MFCD00142870
MOL File:
13659-23-9.mol
MSDS File:
SDS
Last updated:2026-05-28 01:29:56

2-Bromo-5-chlorophenol Properties

Boiling point 222.2±20.0 °C(Predicted)
Density 1.788±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
form solid
pka 7.47±0.10(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
HS Code  2908190090

2-Bromo-5-chlorophenol price More Price(46)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth FB64417 2-Bromo-5-chlorophenol 13659-23-9 10g $173 2026-06-04 Buy
Biosynth FB64417 2-Bromo-5-chlorophenol 13659-23-9 25g $346 2026-06-04 Buy
Biosynth FB64417 2-Bromo-5-chlorophenol 13659-23-9 50g $576.5 2026-06-04 Buy
Biosynth FB64417 2-Bromo-5-chlorophenol 13659-23-9 100g $961 2026-06-04 Buy
Biosynth FB64417 2-Bromo-5-chlorophenol 13659-23-9 250g $1922.5 2026-06-04 Buy
Product number Packaging Price Buy
FB64417 10g $173 Buy
FB64417 25g $346 Buy
FB64417 50g $576.5 Buy
FB64417 100g $961 Buy
FB64417 250g $1922.5 Buy

2-Bromo-5-chlorophenol Chemical Properties, Uses, Production

Chemical Properties

Pale yellow crystalline powder

Chemical Reactivity

The chemical reactions of 2-Bromo-5-chlorophenol include reactions with aminopyridine, isopropyl alcohol, chloroaniline, halophenols, dimethylamine, ethanolamine and toluidine. 2-Bromo-5-chlorophenol has been used as a reagent for the preparation of diethyl ethers and nitrates. This product has been used as a reagent for the synthesis of methyl groups and emulsifying agents for oil and water mixtures.

Synthesis

3-Chlorophenol

108-43-0

2-Bromo-5-chlorophenol

13659-23-9

The general procedure for the synthesis of 2-bromo-5-chlorophenol using 3-chlorophenol as starting material was as follows: 5.03 g (39.1 mmol) of 3-chlorophenol was dissolved in 20 mL of dichloromethane, and the solution was cooled under ice bath conditions. Subsequently, 6.25 g (39.1 mmol) of bromine was added slowly and dropwise. The reaction mixture was gradually warmed to room temperature and stirred continuously for 16 hours. After completion of the reaction, the reaction mixture was diluted with water and phase separation was carried out. The organic phase was dried with magnesium sulfate. The residue was purified by silica gel column chromatography with an eluent ratio of 3:2 dichloromethane to hexane solvent mixture. The elution grade containing the target product 2-bromo-5-chlorophenol was collected and concentrated under reduced pressure to give 2.04 g (25% yield) of the pure product. High-resolution mass spectrometry (HRMS) results: calculated value of C6H4OClBr (M+) was 205.9134; measured value was 205.9125. Elemental analysis (EA) results: calculated value of C, 34.74; H, 1.94; measured value of C, 34.74; H, 1.76.

References

[1] Patent: EP1204659, 2003, B1. Location in patent: Page/Page column 30

Global Suppliers ( 206)
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Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
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Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
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Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64

View Latest Price from 2-Bromo-5-chlorophenol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Bromo-5-chlorophenol pictures 2019-09-02 2-Bromo-5-chlorophenol
13659-23-9
$1.00 1KG 98% 1kg; 10kg; 100kg Career Henan Chemical Co
Phenol,2-broMo-5-chloro- 2-Bromo-5-chlorophenol 98% 2-Bromo-5-chlorophen 2-Bromo-5-chlorophenol, 98% 4-Chloro-2-hydroxybromobenzene 13659-23-9 Heterocycles