SPERMINE NONOATE
- CAS No.
- 136587-13-8
- Chemical Name:
- SPERMINE NONOATE
- Synonyms
- NOC-22;SPER/NO;SPERMINE NONOATE;Spermine NONOate,97%;SpermineNONOate,SPER/NO;Spermine Bis(NO) Adduct;SPERMINE/NITRIC OXIDE COMPLEX;SPERMINE BIS (NITRIC OXIDE) ADDUCT;SPERMINE/NITRIC OXIDE COMPLEX (SPER/NO);Spermine-Nitric oxide complex hydrate
- CBNumber:
- CB5128354
- Molecular Formula:
- C10H26N6O2
- Molecular Weight:
- 262.35
- MDL Number:
- MFCD00210215
- MOL File:
- 136587-13-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Spermine–Nitric oxide complex source of nitric oxide | S150 | 25mg | $197 |
| Spermine NONOate ≥98% | 82150 | 10mg | $53 |
| Spermine NONOate ≥98% | 82150 | 25mg | $126 |
| Spermine NONOate ≥98% | 82150 | 50mg | $225 |
| Spermine NONOate ≥98% | 82150 | 100mg | $344 |
| Melting point | 105-107°C |
|---|---|
| Boiling point | 405.6°C (rough estimate) |
| Density | 1.0879 (rough estimate) |
| refractive index | 1.7000 (estimate) |
| storage temp. | -20°C |
| solubility | methanol: ≥1mg/mL |
| form | White solid |
| pka | 5.47±0.69(Predicted) |
| color | white |
| Water Solubility |
0.1 M NaOH: soluble water: soluble |
| Stability | Stable for 1 year from date of purchase as supplied. Protect from exposure to air or moisture. Buffer solutions are not stable and must be prepared immediately before use. |
| InChI | 1S/C10H26N6O2/c11-5-3-8-13-7-1-2-9-15(10-4-6-12)16(18)14-17/h13,18H,1-12H2/p+3 |
| InChIKey | QPIOUFBAROSIAN-UHFFFAOYSA-Q |
| UNSPSC Code | 12352204 |
SAFETY
Risk and Safety Statements
| Safety Statements | 22-24/25 |
|---|---|
| WGK Germany | WGK 3 |
| Storage Class | 11 - Combustible Solids |
SPERMINE NONOATE price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | S150 | Spermine–Nitric oxide complex source of nitric oxide | 136587-13-8 | 25mg | $197 | 2021-12-16 | Buy |
| Cayman Chemical | 82150 | Spermine NONOate ≥98% | 136587-13-8 | 10mg | $53 | 2026-04-30 | Buy |
| Cayman Chemical | 82150 | Spermine NONOate ≥98% | 136587-13-8 | 25mg | $126 | 2026-04-30 | Buy |
| Cayman Chemical | 82150 | Spermine NONOate ≥98% | 136587-13-8 | 50mg | $225 | 2026-04-30 | Buy |
| Cayman Chemical | 82150 | Spermine NONOate ≥98% | 136587-13-8 | 100mg | $344 | 2026-04-30 | Buy |
SPERMINE NONOATE Chemical Properties,Uses,Production
Description
Spermine NONOate (136587-13-8) is a nitric oxide donor and dissociates to the free amine and NO in a pH dependent manner. The half-life of Spermine NONOate in 0.1 M phosphate buffer at pH 7.4 is 39 min at 37 °C, or 230 min at room temperature.1 Dissociation is essentially instantaneous at a pH of 5.0.
Chemical Properties
Off-White Solid
Uses
A reagent which releases Nitric Oxide into aqueous solutions at controlled rates for in vitro studies.
General Description
Complex of nitric oxide (NO) with spermine. Convenient reagent for preparing aqueous solutions of NO. Half-life (t) of NO release = 230 min (PBS, pH 7.4, 22°C).
Biological Activity
A stable complex of nitric oxide and spermine used to generate a controlled release of nitric oxide in solution (EC 50 = 6.2 μ M for relaxation of rabbit aorta, and t=39 min at 37℃, pH 7.4, aqueous solution).
Biochem/physiol Actions
Product does not compete with ATP.
References
[1] L K KEEFER. “NONOates” (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: convenient nitric oxide dosage forms.[J]. Methods in enzymology, 1996, 268: 281-293. DOI:10.1016/s0076-6879(96)68030-6
SPERMINE NONOATE Preparation Products And Raw materials
SPERMINE NONOATE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4773 | 55 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai Jizhi Biochemical Technology Co. Ltd. | 021-4009004166/18616739031 18616739031 | 3007523370@qq.com | China | 52641 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 57336 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Shanghai Fengyong Biotechnology Co., Ltd. | 021-10000000 13000000000 | gzj@abmole.cn | China | 9332 | 58 |
View Lastest Price from SPERMINE NONOATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-05-04 | Spermine NONOate
136587-13-8
|
$40.00-48.00 | 1KG | 99% | 200tons | Guangzhou Sunton Biotechnology Co., Ltd. |
-
- Spermine NONOate
136587-13-8
- $40.00-48.00
- 99%
- Guangzhou Sunton Biotechnology Co., Ltd.
