ChemicalBook >> CAS DataBase List >>N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride

N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride

N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride structure

CAS No.: 42267-27-6

Chemical Name:: N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride

Synonyms: Lys-NCA;N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride;N6-(Trifluoroacetyl)-N2-carboxy-L-Lysine anhydride;L-Lys(TFA)-NCA;Lysine-TFA-NCA;Creatinine Impurity 4;Meloxicam Impurity 25;L-LYS(TFA)-NCA(42267-27-6);e-Trifluoroacetyl-Lysine, NCA;-N-(4-(2,5-Dioxooxazolidin-4-yl)

CBNumber:: CB51456876

Molecular Formula:: C9H11F3N2O4

Molecular Weight:: 268.19

MDL Number:: MFCD11046652

MOL File:: 42267-27-6.mol

MSDS File:: SDS

Last updated:2026-06-19 07:28:27

Request For Quotation

N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride Properties

Melting point	92-93℃ (DEC.)
Density	1.377
storage temp.	Inert atmosphere,Store in freezer, under -20°C
solubility	DMSO (Slightly), Ethyl Acetate (Slightly)
pka	9.27±0.40(Predicted)
form	Solid
color	White to Off-White
optical activity	Consistent with structure
InChI	InChI=1S/C9H11F3N2O4/c10-9(11,12)7(16)13-4-2-1-3-5-6(15)18-8(17)14-5/h5H,1-4H2,(H,13,16)(H,14,17)/t5-/m0/s1
InChIKey	KWNIHCJDDYRQFW-YFKPBYRVSA-N
SMILES	C(NCCCC[C@H]1C(=O)OC(=O)N1)(=O)C(F)(F)F

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07,GHS05
Signal word	Danger
Hazard statements	H315-H318-H335
Precautionary statements	P280-P305+P351+P338-P310-P264-P280-P302+P352-P321-P332+P313-P362
HS Code	2933.79.8500
REACH Registrations	Active

N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride price More Price(37)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	D5600	(S)-N-[4-(2,5-Dioxooxazolidin-4-yl)butyl]-2,2,2-trifluoroacetamide	42267-27-6	1G	$36	2026-04-30	Buy
TCI Chemical	D5600	(S)-N-[4-(2,5-Dioxooxazolidin-4-yl)butyl]-2,2,2-trifluoroacetamide	42267-27-6	5G	$187	2025-07-31	Buy
Usbiological	290338	N6-Trifluoroacetyl-L-lysine N-carboxyanhydride	42267-27-6	500mg	$333	2026-06-03	Buy
Usbiological	290338	N6-Trifluoroacetyl-L-lysine N-carboxyanhydride	42267-27-6	1g	$446	2026-06-03	Buy
Usbiological	290338	N6-Trifluoroacetyl-L-lysine N-carboxyanhydride	42267-27-6	2g	$602	2026-06-03	Buy

Product number	Packaging	Price	Buy
D5600	1G	$36	Buy
D5600	5G	$187	Buy
290338	500mg	$333	Buy
290338	1g	$446	Buy
290338	2g	$602	Buy

N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride Chemical Properties, Uses, Production

Description

N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride is a N6-trifluoroacetylated lysine derivative that is used in the synthesis of peptides. It is a racemic mixture of L and D forms, which is hydrolyzed to form L-glutamic acid, NH4Cl, and CO2. N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride has been shown to be useful in the formation of bonds between amino acids, such as lysine and dipeptides. The compound is also used for the protection of lysine against oxidation during peptide synthesis.

Chemical Properties

White to Off-White Solid

Uses

L-Lys(Tfa)-NCA (N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride) can be used in the synthesis of new arborescent architectures of poly(L-lysine), called lysine dendrigraft (DGL) polymers.

Uses

Used in the synthesis of new arborescent architectures of poly(L-lysine), called lysine dendrigraft (DGL) polymers. DGL polymers were prepd. through a multiple-generation scheme (up to generation 5) in a weakly acidic aq. medium by polycondensing N.vepsiln.-trifluoroacetyl-L-lysine-N-carboxyanhydride (Lys(Tfa)-NCA) onto the previous generation G(n-1) of DGL, which was used as a macroinitiator.

N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride synthesis

Synthesis of N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride from L-Lysine, N2-(chlorocarbonyl)-N6-(trifluoroacetyl)- (9CI)

N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride Preparation Products And Raw materials

Raw materials

Preparation Products

N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride Suppliers

Global Suppliers ( 153)

Supplier	Tel	Email	Country	ProdList	Advantage
shanghaikeyiyuan Technology Co., Ltd	15316056835	545311776@qq.com	China	76	58
ShenZhen InnoSyn Biotech Co.,Ltd	0755-28351685 18503098468	innosyn@163.com	China	602	55
Sichuan jiayinglai technology CO.,LTD	9018 15982359653	1394531348@qq.com	China	2271	55
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Chemsky（shanghai）International Co.,Ltd.	021-50135380	shchemsky@sina.com	China	32273	50
Shanghai Sunway Pharmaceutical Technology Co., Ltd	13761987713	hxzheng@sunwaypharm.cn	China	8663	57
Shanghai Sphchem Co., Ltd.	021-56491756 13512199871	2819742715@qq.com	China	3994	55
T&W GROUP	021-61551611 13296011611	contact@trustwe.com	China	9884	58
TOKYO CHEMICAL INDUSTRY CO., LTD.	03-36680489	Sales-JP@TCIchemicals.com	Japan	28364	80
TCI Europe	320-37350700	sales@tcieurope.eu	Europe	23654	75

Supplier	Advantage
shanghaikeyiyuan Technology Co., Ltd	58
ShenZhen InnoSyn Biotech Co.,Ltd	55
Sichuan jiayinglai technology CO.,LTD	55
J & K SCIENTIFIC LTD.	76
Chemsky（shanghai）International Co.,Ltd.	50
Shanghai Sunway Pharmaceutical Technology Co., Ltd	57
Shanghai Sphchem Co., Ltd.	55
T&W GROUP	58
TOKYO CHEMICAL INDUSTRY CO., LTD.	80
TCI Europe	75

View Latest Price from N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-15	L-Lys(tfa)-NCA 42267-27-6		1kg	99%+	1T	Sichuan HongRi Pharma-Tech Co.,Ltd
2026-06-18	L-Lys(Tfa)-NCA 42267-27-6	$1.50	1g	99.0% Min	10 Tons	Shaanxi Didu New Materials Co. Ltd
2020-01-06	L-Lys(tfa)-NCA 42267-27-6	$1.00	10g	98%	100kg	Sichuan Jiaying Lai Technology Co.,LTD

L-Lys(tfa)-NCA
42267-27-6
99%+
Sichuan HongRi Pharma-Tech Co.,Ltd

L-Lys(Tfa)-NCA
42267-27-6
$1.50
99.0% Min
Shaanxi Didu New Materials Co. Ltd

L-Lys(tfa)-NCA
42267-27-6
$1.00
98%
Sichuan Jiaying Lai Technology Co.,LTD

N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride Spectrum

N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride(42267-27-6)¹HNMR

42267-27-6 (N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride) Related Search:

N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride (4S)-4-Butyl-2-oxazolidinone N-6-Trifluoroacetyl-L-lysine 6-(Trifluoroacetylamino)-1-hexanol N6-Carbobenzoxy-L-lysine N-Carboxyanhydride

N-[4-[(4R)-2,5-Dioxo-4-oxazolidinyl]butyl]-2,2,2-trifluoroacetamide

1of2

N-[4-[(4S)-2,5-dioxooxazolidin-4-yl]butyl]-2,2,2-trifluoro-acetamide e-Trifluoroacetyl-Lysine, NCA N-Trifluoroacetyl-L-lysine N-carboxyanhydride N-(4-(2,5-Dioxo-4-oxazolidinyl)butyl)-2,2,2-trifluoroacetamide N6-Trifluoroacetyl-L-lysine N-Carboxyanhydride L-Lysine-N-Trifluoroacetyl-N-Carboxyanhydride (S)-N-[4-(2,5-Dioxo-4-oxazolidinyl)butyl]-2,2,2-trifluoroacetaMide N-[4-[(4S)-2,5-Dioxo-4-oxazolidinyl]butyl]-2,2,2-trifluoroacetaMide AcetaMide,N-[4-[(4S)-2,5-dioxo-4-oxazolidinyl]butyl]-2,2,2-trifluoro- N-[3-[(4S)-2,5-dioxooxazolidin-4-yl]propyl]-2,2,2-trifluoro-acetaMide N-trifluoroacetyl lysine N-carboxyanhydride 4-[(4S)-2,5-DIOXOOXAZOLIDIN-4-YL]BUTYL]-2,2,2-TRIFLUORO-ACETAMIDE (S)-N-(4-(2,5-Dioxooxazolidin-4-yl)-butyl)-2,2,2-trifluoroacetamide L-Lys(TFA)-NCA -N-(4-(2,5-Dioxooxazolidin-4-yl) L-LYS(TFA)-NCA(42267-27-6) Lysine-TFA-NCA N-[4-[(4S)-2,5-dioxo-1,3-oxazolidin-4-yl]butyl]-2,2,2-trifluoroacetamide Nepsilon-Trifluoroacetyl-Nalpha-carboxy-L-lysine Anhydride Acetamide, N-(4-(2,5-dioxo-4-oxazolidinyl)butyl)-2,2,2-trifl... Creatinine Impurity 4 Ne-trifluoroacetyl L-lysine intracyclic anhydride Meloxicam Impurity 25 Acetamide, N-(4-(2,5-dioxo-4-oxazolidinyl)butyl)-2,2,2-trifluo Lys-NCA N6-(Trifluoroacetyl)-N2-carboxy-L-Lysine anhydride N-(4-(2,5-Dioxooxazolidin-4-yl)butyl)-2,2,2-trifluoroacetamide N-[4-(2,5-Dioxo-4(S)-oxazolidinyl)butyl]-2,2,2-trifluoroacetamide 42267-27-6 C9H11F3N2O4 AMINOACIDS DERIVATIVES Amino Acids & Derivatives Aromatics Chiral Reagents Heterocycles