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N-6-Trifluoroacetyl-L-lysine

N-6-Trifluoroacetyl-L-lysine structure

CAS No.: 10009-20-8

Chemical Name:: N-6-Trifluoroacetyl-L-lysine

Synonyms: H-LYS(TFA)-OH;N6-(2,2,2-Trifluoroacetyl)-L-lysine;Ε-TFA-LYSINE;LYR(TFA)-TYR;LYS(TFA)-TYR;L-Lys(Tfa)-OH;LYSINE(TFA)-OH;H-LYS(CF3CO)-OH;EPSILON-TFA-LYSINE;n(epsilon)-trifluoro

CBNumber:: CB4249490

Molecular Formula:: C8H13F3N2O3

Molecular Weight:: 242.2

MDL Number:: MFCD00037223

MOL File:: 10009-20-8.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-28 02:02:48

Product description	Number	Pack Size	Price
Nε-Trifluoroacetyl-L-lysine ≥96.0% (TLC)	53604	5G	$77.8
Nε-Trifluoroacetyl-L-lysine ≥96.0% (TLC)	53604	25g	$229
Nε-Trifluoroacetyl-L-lysine >98.0%(T)	T2815	5g	$19
Nε-Trifluoroacetyl-L-lysine >98.0%(T)	T2815	25g	$51
Ne-Trifluoroacetyl-L-lysine Asreported	285625	10g	$333
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N-6-Trifluoroacetyl-L-lysine Properties

Melting point	258
Boiling point	382.5±42.0 °C(Predicted)
Density	1.4
storage temp.	Keep in dark place,Sealed in dry,2-8°C
solubility	2 M HCl: 10 mg/mL, clear, colorless
pka	2.51±0.24(Predicted)
form	Solid
color	Off-White
BRN	2122429
Major Application	peptide synthesis
InChI	InChI=1S/C8H13F3N2O3/c9-8(10,11)7(16)13-4-2-1-3-5(12)6(14)15/h5H,1-4,12H2,(H,13,16)(H,14,15)/t5-/m0/s1
InChIKey	PZZHRSVBHRVIMI-YFKPBYRVSA-N
SMILES	C(O)(=O)[C@H](CCCCNC(C(F)(F)F)=O)N
UNSPSC Code	12352209
NACRES	NA.26

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P301+P312-P302+P352-P304+P340-P305+P351+P338
PPE	Eyeshields, Gloves, type N95 (US)
Safety Statements	22-24/25
WGK Germany	1
F	10
HS Code	29241990
Storage Class	11 - Combustible Solids
REACH Registrations	Active

N-6-Trifluoroacetyl-L-lysine price More Price(88)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	53604	Nε-Trifluoroacetyl-L-lysine ≥96.0% (TLC)	10009-20-8	5G	$77.8	2025-07-31	Buy
Sigma-Aldrich	53604	Nε-Trifluoroacetyl-L-lysine ≥96.0% (TLC)	10009-20-8	25g	$229	2023-06-20	Buy
TCI Chemical	T2815	Nε-Trifluoroacetyl-L-lysine >98.0%(T)	10009-20-8	5g	$19	2026-04-30	Buy
TCI Chemical	T2815	Nε-Trifluoroacetyl-L-lysine >98.0%(T)	10009-20-8	25g	$51	2026-04-30	Buy
Usbiological	285625	Ne-Trifluoroacetyl-L-lysine Asreported	10009-20-8	10g	$333	2026-06-03	Buy

Product number	Packaging	Price	Buy
53604	5G	$77.8	Buy
53604	25g	$229	Buy
T2815	5g	$19	Buy
T2815	25g	$51	Buy
285625	10g	$333	Buy

N-6-Trifluoroacetyl-L-lysine Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

A cysteine conjugate metabolite adduct formation with specific mitochondrial proteins using antibodies raised against halothane metabolite adducts.

Definition

ChEBI: An N6-acyl-L-lysine where the N6-acyl group is trifluoroacetyl.

Biological Activity

Nε-Trifluoroacetyl-L-lysine is an inhibitor of L-lysine cyclodeaminase.', 'Nε-Trifluoroacetyl-L-lysine may be used to create synthetic organic polypeptides useful for nonaqueous capillary electrophoresis (NACE).

Synthesis

383-63-1

657-27-2

10009-20-8

1. Sodium ethanolate solution was prepared by dissolving sodium metal (4.6 g, 0.2 mol) in 200 mL of anhydrous ethanol. 2. L-lysine hydrochloride (18.25 g, 0.1 mol) was slowly added to the above solution under stirring conditions. 3. The reaction mixture was stirred continuously for 1 hour, followed by filtration to remove the insoluble precipitate. 4. The filtrate was cooled in an ice bath and ethyl trifluoroacetate (21.3 g, 0.15 mol) was added slowly and dropwise with vigorous stirring. 5. The reaction mixture was gradually warmed to room temperature and stirring was continued for 2 hours. 6. Acetic acid (6 g, 0.1 mol) was added to neutralize the reaction system and the resulting precipitate was subsequently collected by filtration. 7. The precipitate was washed sequentially with ethanol and acetone and dried to give the target product trifluoroacetyl lysine. 8. Yield: 15 g (62% yield). 9. MALDI-TOF mass spectrometry (positive ion mode): m/z 242.455 ([M+H]+, relative abundance 67%).

References

[1] Russian Journal of Organic Chemistry, 2007, vol. 43, # 10, p. 1427 - 1431
[2] Patent: WO2009/114809, 2009, A1. Location in patent: Page/Page column 7
[3] Bioorganic and Medicinal Chemistry Letters, 2011, vol. 21, # 1, p. 255 - 258

N-6-Trifluoroacetyl-L-lysine Preparation Products And Raw materials

Raw materials

Ethyl trifluoroacetate L-Lysine hydrochloride Acetic acid Ethanol

Preparation Products

N-6-Trifluoroacetyl-L-lysine Suppliers

Global( 426)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
airuikechemical co., ltd.	+86-18353166132	sales02@airuikechemical.com	China	983	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718 +86-13336195806	sales@capot.com	China	29640	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	14014	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21586	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29812	58
Jinan Finer Chemical Co., Ltd	+86-531-88989536 +86-15508631887	sales@finerchem.com	China	2950	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5906	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19936	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58

Supplier	Advantage
airuikechemical co., ltd.	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Jinan Finer Chemical Co., Ltd	58
Shandong chuangyingchemical Co., Ltd.	58
BOC Sciences	58
Alchem Pharmtech,Inc.	58

View Lastest Price from N-6-Trifluoroacetyl-L-lysine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-05-11	H-Lys(Tfa)-OH 10009-20-8	$29.00		99.35%	10g	TargetMol Chemicals Inc.
2026-05-11	H-Lys(Tfa)-OH 10009-20-8	$29.00		99.35%	10g	TargetMol Chemicals Inc.
2025-04-04	N-6-Trifluoroacetyl-L-lysine 10009-20-8		1KG	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.

H-Lys(Tfa)-OH
10009-20-8
$29.00
99.35%
TargetMol Chemicals Inc.

H-Lys(Tfa)-OH
10009-20-8
$29.00
99.35%
TargetMol Chemicals Inc.

N-6-Trifluoroacetyl-L-lysine
10009-20-8
98%
Henan Aochuang Chemical Co.,Ltd.

N-6-Trifluoroacetyl-L-lysine Spectrum

N-6-Trifluoroacetyl-L-lysine(10009-20-8)¹HNMR

10009-20-8(N-6-Trifluoroacetyl-L-lysine)Related Search:

Trifluoroacetyl chloride BOC-TRP-N(OCH3)CH3 HEXAFLUOROACETYLACETONE Acetylacetone Triethyl acetyl citrate

Poly-L-lysine N-ACETYL-L-TYROSINE ETHYL ESTER DL-Lysine acetylsalicylate L-Lysine 3,3-Dimethyl-2-oxobutyric acid

Sodium triacetoxyborohydride H-Lys-OBzl·HCl·TosOH Ethyl 2,6-diaminohexanoate dihydrochloride 6-Azido-L-norleucine HCl H-Lys(Mtt)-OH

H-Lys-Leu-Lys-OH N6-Cbz-L-Lysine benzyl ester hydrochloride Lysine(propionyl)- OH

1of4

H-LYS(CF3CO)-OH EPSILON-TFA-LYSINE LYSINE(TFA)-OH N-EPSILON-TRIFLUOROACETYL-L-LYSINE N6-TRIFLUOROACETYL-L-LYSINE N6-Trrifluoroacetyl-L-lysine(for Lisinopril) N6-Trifluoroacetyl-L-lysine 98% INTERMEDIATE OF QUINAPRIL/N6-TRIFLUOROACETYL-L-LYSINE N-6-TRIFLUORO ACETYL-L-LYSINE ( LISINOPRIL INTERMEDIATE ) N6-Trifluoroacetyl-L-lysine98% N(6)-Trifluoracetyl-L-Lysin Ε-TFA-LYSINE N-ε-Trifluoroacetyl-L-lysine N1-Trifluoroacetyl-L-Lysine N6-Trifluoroaccety-L-lysine N6-Trifluoroacetyl-L-lysine (for lisinopril) (2S)-2-amino-6-(2,2,2-trifluoroacetamido)hexanoic acid (2S)-2-amino-6-(trifluoroacetamido)hexanoic acid (S)-2-aMino-6-(2,2,2-trifluoroacetaMido)hexanoic acid n(epsilon)-trifluoro N-E-TRIFLUOROACETYL-L-LYSINE Trifluoroacetyllysine LYR(TFA)-TYR N6-Tryfluoro Acetyl-L-Lysine N^ε-Trifluoroacetyl-L-lysine (S)-2-AMino-6-(2,2,2-trifluoro-acetylaMino)-hexanoic acid LYS(TFA)-TYR L-Lys(Tfa)-OH Nε-Trifluoroacetyl-L-lysine≥ 99% (Assay) ε-TFA-lysine H-Lys(Tfa)-OH Lys(tfa)-OH / K(Tfa) L-Lysine, N6-(2,2,2-trifluoroacetyl)- N-6-Trifluoroacetyl-L-lysine USP/EP/BP N-6-Trifluoroacetyl-L-Lysine extrapure, 98% Nε-Trifluoroacetyl Lysine N_ε-Trifluoroacetyl-L-lysine (S)-2-Amino-6-(2,2,2-trifluoro-acetcarboxcarboxcarboxamido)-hexanoic acid H-LYS(TFA)-OH N6-(2,2,2-Trifluoroacetyl)-L-lysine 10009-20-8 10009-60-8 C8H13F3N2O3 C8H13N2O3F3 Specialty Synthesis Lysine Peptide Synthesis Amino Acid Derivatives Amino Acids & Derivatives, Metabolites & Impurities Amino Acids & Derivatives Metabolites & Impurities amino acid API intermediates Chemical intermediate for LISINOPRIL 10009-20-8