ChemicalBook >> CAS DataBase List >>6-(2,2,2-trifluoroethoxy)pyridin-3-amine

6-(2,2,2-trifluoroethoxy)pyridin-3-amine

CAS No.
72617-82-4
Chemical Name:
6-(2,2,2-trifluoroethoxy)pyridin-3-amine
Synonyms
6-(2,2,2-Trifluoroethoxy);6-(2,2,2-Trifluoroethoxy)-3-pyridinaMine;6-(2,2,2-trifluoroethoxy)pyridin-3-amine;3-Pyridinamine, 6-(2,2,2-trifluoroethoxy)-
CBNumber:
CB51780683
Molecular Formula:
C7H7F3N2O
Molecular Weight:
192.14
MDL Number:
MFCD04111379
MOL File:
72617-82-4.mol
MSDS File:
SDS
Last updated:2026-05-28 02:06:28
Product description Number Pack Size Price
6-(2,2,2-Trifluoroethoxy)pyridin-3-amine 97% PC201293 100mg $21
6-(2,2,2-Trifluoroethoxy)pyridin-3-amine 97% PC201293 250mg $24
6-(2,2,2-Trifluoroethoxy)pyridin-3-amine 97% PC201293 1g $52
6-(2,2,2-Trifluoroethoxy)pyridin-3-amine 97% PC201293 5g $240
6-(2,2,2-Trifluoroethoxy)pyridin-3-amine 97% PC201293 100mg $21
More product size

6-(2,2,2-trifluoroethoxy)pyridin-3-amine Properties

Boiling point 247.9±40.0 °C(Predicted)
Density 1.354±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 3.70±0.22(Predicted)
Appearance Light yellow to brown Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501
HS Code  2933399990

6-(2,2,2-trifluoroethoxy)pyridin-3-amine price More Price(58)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific PC201293 6-(2,2,2-Trifluoroethoxy)pyridin-3-amine 97% 72617-82-4 100mg $21 2026-06-04 Buy
Apolloscientific PC201293 6-(2,2,2-Trifluoroethoxy)pyridin-3-amine 97% 72617-82-4 250mg $24 2026-06-04 Buy
Apolloscientific PC201293 6-(2,2,2-Trifluoroethoxy)pyridin-3-amine 97% 72617-82-4 1g $52 2026-06-04 Buy
Apolloscientific PC201293 6-(2,2,2-Trifluoroethoxy)pyridin-3-amine 97% 72617-82-4 5g $240 2026-06-04 Buy
Apolloscientific PC201293 6-(2,2,2-Trifluoroethoxy)pyridin-3-amine 97% 72617-82-4 100mg $21 2026-06-04 Buy
Product number Packaging Price Buy
PC201293 100mg $21 Buy
PC201293 250mg $24 Buy
PC201293 1g $52 Buy
PC201293 5g $240 Buy
PC201293 100mg $21 Buy

6-(2,2,2-trifluoroethoxy)pyridin-3-amine Chemical Properties,Uses,Production

Synthesis

5-NITRO-2-(2,2,2-TRIFLUOROETHOXY)PYRIDINE

72617-81-3

6-(2,2,2-trifluoroethoxy)pyridin-3-amine

72617-82-4

Step 2: Synthesis of 6-(2,2,2-trifluoroethoxy)-3-pyridinamine 5-Nitro-2-(2,2,2-trifluoroethoxy)pyridine (20.5 g, obtained from Example 108 Step 1) was dissolved in methanol (160 mL). Palladium/activated carbon catalyst (1.96 g, 10% Pd) was added to the solution and hydrogen was passed through at room temperature. The reaction mixture was stirred under hydrogen atmosphere for 72 hours. Upon completion of the reaction, the reaction mixture was filtered using Dicalite Speed Plus (Acros Organics) and the filter cake was washed with ethyl acetate. The filtrate was concentrated under reduced pressure to remove the solvent. The resulting residue was purified by fast column chromatography (silica gel as stationary phase, heptane/ethyl acetate gradient elution) to afford 6-(2,2,2-trifluoroethoxy)-3-pyridinamine as a brown liquid (16.49 g, 91% yield). Mass spectrometry (MS) data: m/e 193.1 [MH+].

References

[1] Patent: WO2011/45292, 2011, A1. Location in patent: Page/Page column 176
[2] Patent: US2011/92512, 2011, A1. Location in patent: Page/Page column 55
[3] Patent: US2004/63738, 2004, A1
[4] Patent: JP2015/86180, 2015, A. Location in patent: Paragraph 0040

6-(2,2,2-trifluoroethoxy)pyridin-3-amine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 63)Suppliers
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HaBo Hong Kong Co., Limited.
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SHANGHAI KEAN TECHNOLOGY CO., LTD.
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Amadis Chemical Company Limited
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Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10975 64
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8666 57

6-(2,2,2-trifluoroethoxy)pyridin-3-amine Spectrum

6-(2,2,2-trifluoroethoxy)pyridin-3-amine 6-(2,2,2-Trifluoroethoxy)-3-pyridinaMine 6-(2,2,2-Trifluoroethoxy) 3-Pyridinamine, 6-(2,2,2-trifluoroethoxy)- 72617-82-4