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6-(2,2,2-trifluoroethoxy)pyridin-3-amine

6-(2,2,2-trifluoroethoxy)pyridin-3-amine Structure
6-(2,2,2-trifluoroethoxy)pyridin-3-amine structure
CAS No.
72617-82-4
Chemical Name:
6-(2,2,2-trifluoroethoxy)pyridin-3-amine
Synonyms
6-(2,2,2-Trifluoroethoxy);6-(2,2,2-Trifluoroethoxy)-3-pyridinaMine;6-(2,2,2-trifluoroethoxy)pyridin-3-amine;3-Pyridinamine, 6-(2,2,2-trifluoroethoxy)-
CBNumber:
CB51780683
Molecular Formula:
C7H7F3N2O
Molecular Weight:
192.14
MDL Number:
MFCD04111379
MOL File:
72617-82-4.mol
MSDS File:
SDS
Last updated:2026-05-28 02:06:28
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6-(2,2,2-trifluoroethoxy)pyridin-3-amine Properties

Boiling point 247.9±40.0 °C(Predicted)
Density 1.354±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 3.70±0.22(Predicted)
Appearance Light yellow to brown Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P305+P351+P338-P337+P313-P261-P271-P304+P340-P312-P403+P233-P405-P501
HS Code  2933399990

6-(2,2,2-trifluoroethoxy)pyridin-3-amine price More Price(43)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific PC201293 6-(2,2,2-Trifluoroethoxy)pyridin-3-amine 97% 72617-82-4 100mg $21 2026-06-04 Buy
Apolloscientific PC201293 6-(2,2,2-Trifluoroethoxy)pyridin-3-amine 97% 72617-82-4 250mg $24 2026-06-04 Buy
Apolloscientific PC201293 6-(2,2,2-Trifluoroethoxy)pyridin-3-amine 97% 72617-82-4 1g $52 2026-06-04 Buy
Apolloscientific PC201293 6-(2,2,2-Trifluoroethoxy)pyridin-3-amine 97% 72617-82-4 5g $240 2026-06-04 Buy
Activate Scientific AS26135 6-(2,2,2-Trifluoroethoxy)-3-pyridinamine 96% 72617-82-4 250mg $99 2026-06-04 Buy
Product number Packaging Price Buy
PC201293 100mg $21 Buy
PC201293 250mg $24 Buy
PC201293 1g $52 Buy
PC201293 5g $240 Buy
AS26135 250mg $99 Buy

6-(2,2,2-trifluoroethoxy)pyridin-3-amine Chemical Properties, Uses, Production

Synthesis

5-NITRO-2-(2,2,2-TRIFLUOROETHOXY)PYRIDINE

72617-81-3

6-(2,2,2-trifluoroethoxy)pyridin-3-amine

72617-82-4

Step 2: Synthesis of 6-(2,2,2-trifluoroethoxy)-3-pyridinamine 5-Nitro-2-(2,2,2-trifluoroethoxy)pyridine (20.5 g, obtained from Example 108 Step 1) was dissolved in methanol (160 mL). Palladium/activated carbon catalyst (1.96 g, 10% Pd) was added to the solution and hydrogen was passed through at room temperature. The reaction mixture was stirred under hydrogen atmosphere for 72 hours. Upon completion of the reaction, the reaction mixture was filtered using Dicalite Speed Plus (Acros Organics) and the filter cake was washed with ethyl acetate. The filtrate was concentrated under reduced pressure to remove the solvent. The resulting residue was purified by fast column chromatography (silica gel as stationary phase, heptane/ethyl acetate gradient elution) to afford 6-(2,2,2-trifluoroethoxy)-3-pyridinamine as a brown liquid (16.49 g, 91% yield). Mass spectrometry (MS) data: m/e 193.1 [MH+].

References

[1] Patent: WO2011/45292, 2011, A1. Location in patent: Page/Page column 176
[2] Patent: US2011/92512, 2011, A1. Location in patent: Page/Page column 55
[3] Patent: US2004/63738, 2004, A1
[4] Patent: JP2015/86180, 2015, A. Location in patent: Paragraph 0040

6-(2,2,2-trifluoroethoxy)pyridin-3-amine Preparation Products And Raw materials

Raw materials

5-Nitro-2-(2,2,2-trifluoroethoxy)pyridine Hydrogen Methanol

Preparation Products

6-(2,2,2-trifluoroethoxy)pyridin-3-amine Suppliers

Global Suppliers ( 63)
Supplier Tel Email Country ProdList Advantage
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8663 57
Nanjing Norris-Pharm Technology Co., Ltd 13901585132 sales@norris-pharm.com China 8869 55
CEG Chemical Science&Technology Co., Ltd. Mobile:13665161512 China 1784 58
Shanghai Carlow Chemicals Co., Ltd. 21-33526724 18930996265 info@carlowchem.com China 1996 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Nantong MYBio-pharm. Co., Ltd. 0513-85921823 18662920231 sales@ntminyanmedical.com China 4565 58
Cool Pharm, Ltd 021-60455363 18019463053 sales@coolpharm.com China 8455 58
Accela ChemBio Inc. +1(858) 699-3322 marketing@accelachem.com United States 6022 65
Shanghai DongYang Biotechnology Co., Ltd. 18657622632 chemsharker@126.com China 371 55
Supplier Advantage
Accela ChemBio Co.,Ltd. 64
Shanghai Sunway Pharmaceutical Technology Co., Ltd 57
Nanjing Norris-Pharm Technology Co., Ltd 55
CEG Chemical Science&Technology Co., Ltd. 58
Shanghai Carlow Chemicals Co., Ltd. 58
Bide Pharmatech Ltd. 60
Nantong MYBio-pharm. Co., Ltd. 58
Cool Pharm, Ltd 58
Accela ChemBio Inc. 65
Shanghai DongYang Biotechnology Co., Ltd. 55

6-(2,2,2-trifluoroethoxy)pyridin-3-amine Spectrum

6-(2,2,2-trifluoroethoxy)pyridin-3-amine(72617-82-4)1HNMR

72617-82-4 (6-(2,2,2-trifluoroethoxy)pyridin-3-amine) Related Search:

6-Piperidin-1-ylpyrazine-2-carboxylic acid 6-(2,2,2-Trifluoroethoxy)nicotinic acid methyl ester 6-(2,2,2-Trifluoro-ethoxy)-pyridine-3-carbaldehyde 6-Methoxy-3,4-dihydro-2H-isoquinolin-1-one 6-(pyrrolidin-1-yl)-9H-purin-2-aMine
6-(4-Methylpiperazin-1-yl)-1H-indole 6-(4-Methylpiperazin-1-yl)pyridazin-3-aMine 6-(Hydroxymethyl)pyridine-2-carboxaldehyde Imidazo[1,2-a]pyridine-6-boronic acic pinacol ester 6-(MethoxyMethyl)picolinaldehyde
3-Pyridazinecarboxylicacid,6-(methylamino)-(9CI)

1of3

6-(2,2,2-trifluoroethoxy)pyridin-3-amine 6-(2,2,2-Trifluoroethoxy)-3-pyridinaMine 6-(2,2,2-Trifluoroethoxy) 3-Pyridinamine, 6-(2,2,2-trifluoroethoxy)- 72617-82-4