5-Benzylidenehydantoin
- CAS No.
- 3775-01-7
- Chemical Name:
- 5-Benzylidenehydantoin
- Synonyms
- RARECHEM AP KH 0029;TIMTEC-BB SBB007867;Benzylidene hydantoin;5-Benzylidendhydantoin;5-BENZYLIDENEHYDANTOIN;5-phenylmethylenehydantoin;5-Benzylideneimidazolidine-2,4-dione;5-Benzylidene-2,4-imidazolidinedione;(5E)-5-Benzylidene-2,4-imidazolidinedione;2,4-Imidazolidinedione, 5-(phenylmethylene)-
- CBNumber:
- CB5179770
- Molecular Formula:
- C10H8N2O2
- Molecular Weight:
- 188.18
- MDL Number:
- MFCD00014494
- MOL File:
- 3775-01-7.mol
5-Benzylidenehydantoin price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 172046 | 5-Benzylidenehydantoin | 3775-01-7 | 5.00g | $118 | 2026-05-18 | Buy |
| Matrix Scientific | 172046 | 5-Benzylidenehydantoin | 3775-01-7 | 25.00g | $370 | 2026-05-18 | Buy |
| aablocks | AA00C7D8 | 5-Benzylideneimidazolidine-2,4-dione | 3775-01-7 | 5g | $108 | 2026-05-28 | Buy |
| aablocks | AA00C7D8 | 5-Benzylideneimidazolidine-2,4-dione | 3775-01-7 | 25g | $263 | 2026-05-28 | Buy |
| ACHEMBLOCK | AD268559 | 5-Benzylideneimidazolidine-2,4-dione 95% | 3775-01-7 | 5G | $345 | 2026-05-27 | Buy |
5-Benzylidenehydantoin Chemical Properties, Uses, Production
Description
Derivatives of 5-Benzylidenehydantoin are well known of their various attractive bioactivities such as anticancer, antimicrobial, antidiabetic and tyrosinase inhibitor. UPR1024 belongs to a new class of EGFR inhibitors characterized by a hydantoin nucleus and a 5-benzylidene substituent having a double bond conjugated with a carbonyl group on the hydantoin ring. The compound had antiproliferative and proapoptotic effects when tested on the non-small cell lung cancer cell line A549[1-2].
Biological Activity
5-Benzylidenehydantoins inhibited the EGFR kinase and exhibited an antiproliferative action on A431 human epidermoid carcinoma cells. The conjugated exo-cyclic double bond at the C5 position appeared essential for both EGFR and cell growth inhibition, indicating that the 5-benzylidene hydantoin core would be a suitable scaffold for generating new antiproliferative compounds[3].
References
[1] Haq, K. U. et al. “Synthesis of 5-benzylidene-hydantoin and 5-benzylidene-creatinine derivatives under mixed catalyst systems of urea-p-toluenesulfonic acid (Urea-PTSA) and guanidine hydrochloride-triethylamine (GnHCl-TEA).”(2020).
[2] Andrea Cavazzoni. “Dual mechanisms of action of the 5-benzylidene-hydantoin UPR1024 on lung cancer cell lines.” Molecular Cancer Therapeutics 7 2 (2008): 361–70.
5-Benzylidenehydantoin Preparation Products And Raw materials
Raw materials
Preparation Products
5-Benzylidenehydantoin Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| SHIJIAZHUANG DONGHUA JINLONG CHEMICAL CO.,LTD. | 0311-66619688 15632114516 | donghuajinlong@glycine.com.cn | China | 14 | 58 |
| Chengdu HappySyn Pharmaceutical Technology Co., Ltd. | 85114309 18982182443 | yangli@happysyn.com | China | 2297 | 55 |
| Yantai ShengKailun Chemical Technology Co., Ltd. | 13356901049 | 3119594100@qq.com | China | 7964 | 55 |
| Beijing Hihealth Pharma. Sci. & Tech. Co.,Ltd. | 13911823113 | hihealth@sina.com | China | 59 | 58 |
| Beijing Minruida Technology Co., Ltd. | 010-82387566 | sales@mreda.com.cn | China | 19323 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-173 9270 1263 | 1057@dideu.com | China | 3960 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-17392712779 | 1097@dideu.com | China | 3989 | 58 |
| Shandong WorldSun Biological Technology Co., Ltd. | 0531-88723173 18596073690 | 1047208234@qq.com | China | 8177 | 58 |
| SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD | 0755-83725350 13380397412 | 3001280422@qq.com | China | 10000 | 58 |
| Wuhan Fortuna Chemical Co., Ltd | 027-59207852 13308628970 | buy@fortunachem.com | China | 2579 | 58 |
View Latest Price from 5-Benzylidenehydantoin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-12-24 | 5-BENZYLIDENEHYDANTOIN
3775-01-7
|
1KG | 99.0% | 1000 tons | Shaanxi Dideu Medichem Co. Ltd | ||
 |
2025-04-24 | 5-Benzylidene Hydantoin
3775-01-7
|
25kg | 99% | 2000 | Shijiazhuang Donghua Jinlong Chemical Co., LTD | ||
 |
2025-04-24 | 5-Benzylidene Hydantoin
3775-01-7
|
20kg | 99% | 2000mt | Shijiazhuang Donghua Jinlong Chemical Co., LTD |
-
- 5-BENZYLIDENEHYDANTOIN
3775-01-7
- $0.10
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- 5-Benzylidene Hydantoin
3775-01-7
- $0.00
- 99%
- Shijiazhuang Donghua Jinlong Chemical Co., LTD
-
- 5-Benzylidene Hydantoin
3775-01-7
- $0.00
- 99%
- Shijiazhuang Donghua Jinlong Chemical Co., LTD
3775-01-7 (5-Benzylidenehydantoin) Related Search:
1of3
