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ChemicalBook >> CAS DataBase List >>2-(4-Hydroxybenzyl)-3-(4-hydroxyphenyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-2-carboxylic acid methyl ester

2-(4-Hydroxybenzyl)-3-(4-hydroxyphenyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-2-carboxylic acid methyl ester

2-(4-Hydroxybenzyl)-3-(4-hydroxyphenyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-2-carboxylic acid methyl ester Structure
2-(4-Hydroxybenzyl)-3-(4-hydroxyphenyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-2-carboxylic acid methyl ester structure
CAS No.
87414-44-6
Chemical Name:
2-(4-Hydroxybenzyl)-3-(4-hydroxyphenyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-2-carboxylic acid methyl ester
Synonyms
Butyrolactone II;2,5-Dihydro-4-hydroxy-2-(4-hydroxybenzyl)-3-(4-hydroxyphenyl)-5-oxofuran-2-carboxylic acid methyl ester;2,5-Dihydro-2-(4-hydroxybenzyl)-3-(4-hydroxyphenyl)-4-hydroxy-5-oxo-2-furancarboxylic acid methyl ester;2-(4-Hydroxybenzyl)-3-(4-hydroxyphenyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-2-carboxylic acid methyl ester;2-Furancarboxylic acid, 2,5-dihydro-4-hydroxy-3-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-5-oxo-, methyl ester, (2R)-
CBNumber:
CB52331806
Molecular Formula:
C19H16O7
Molecular Weight:
356.33
MDL Number:
MFCD09752715
MOL File:
87414-44-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:59:02
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2-(4-Hydroxybenzyl)-3-(4-hydroxyphenyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-2-carboxylic acid methyl ester Properties

Melting point 91-94 °C
Boiling point 640.5±55.0 °C(Predicted)
Density 1.497±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
form Amorphous.
pka 8.61±0.40(Predicted)
color White to off-white

SAFETY

Risk and Safety Statements

HS Code  29419000

2-(4-Hydroxybenzyl)-3-(4-hydroxyphenyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-2-carboxylic acid methyl ester price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 29943 Butyrolactone II ≥95% 87414-44-6 1mg $303 2026-04-30 Buy
Cayman Chemical 29943 Butyrolactone II ≥95% 87414-44-6 5mg $902 2026-04-30 Buy
Usbiological 443690 Butyrolactone II 87414-44-6 500ug $453 2026-06-03 Buy
Usbiological 443690 Butyrolactone II 87414-44-6 1000ug $644 2026-06-03 Buy
Adipogen Life Sciences AG-CN2-0423-C500 Butyrolactone II ≥97%(HPLC) 87414-44-6 500μg $140 2026-05-06 Buy
Product number Packaging Price Buy
29943 1mg $303 Buy
29943 5mg $902 Buy
443690 500ug $453 Buy
443690 1000ug $644 Buy
AG-CN2-0423-C500 500μg $140 Buy

2-(4-Hydroxybenzyl)-3-(4-hydroxyphenyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-2-carboxylic acid methyl ester Chemical Properties,Uses,Production

Description

Butyrolactone II is a butenolide fungal metabolite that has been found in A. terreus. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) and ABTS free radicals (EC50s = 11.5 and 68.5 μM, respectively). It inhibits 5-lipoxygenase (5-LO; IC50 = 21.43 μg/ml) and α-glucosidase (IC50 = 0.126 mM).

Uses

Butyrolactone II is an antibiotic, a 5-LOX inhibitor and has shown DPPH radical-scavening activity.

IC 50

Microbial Metabolite

storage

+4°C

References

[1] HAHK-SOO KANG  Jong P K. Butenolide derivatives from the fungus Aspergillus terreus and their radical scavenging activity and protective activity against glutamate-induced excitotoxicity[J]. Applied Biological Chemistry, 2019, 62 1. DOI: 10.1186/s13765-019-0451-3
[2] FU-SHENG WANG B Z. Butyrolactones, inhibitors of 5-lipoxygenase from fungal metabolites[J]. Journal of Chinese Pharmaceutical Sciences, 2010, 19 1. DOI: 10.5246/jcps.2010.04.035
[3] LI-HUA ZHANG . Polyketide butenolide, diphenyl ether, and benzophenone derivatives from the fungus Aspergillus flavipes PJ03-11[J]. Bioorganic & Medicinal Chemistry Letters, 2016, 26 2: Pages 346-350. DOI: 10.1016/j.bmcl.2015.12.009

2-(4-Hydroxybenzyl)-3-(4-hydroxyphenyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-2-carboxylic acid methyl ester synthesis

154722-74-4
87414-44-6
Synthesis of 2-(4-Hydroxybenzyl)-3-(4-hydroxyphenyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-2-carboxylic acid methyl ester from Benzenepropanoic acid, 4-hydroxy-α-oxo-, methyl ester

2-(4-Hydroxybenzyl)-3-(4-hydroxyphenyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-2-carboxylic acid methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

2-(4-Hydroxybenzyl)-3-(4-hydroxyphenyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-2-carboxylic acid methyl ester Suppliers

Global( 24)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Winherb Medical Technology Co., Ltd. 17301719108 13341702378 winherb@126.com China 1245 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11123 58
Meng Cheng Technology (Shanghai) Co., LTD 400-820-6829 sales@mitachieve.com China 8857 58
Shanghai Moqi Biological Technology Co., LTD 13341702378 190129269@qq.com China 9998 58
Shanghai Yiyan Biotechnology Co. , Ltd. 021-69985186 13611928337 3427709316@qq.com China 7982 58
Shanghai Saikerui Biotechnology Co. , Ltd. 021-58000709 13120558703 sales@scrbio.com China 9873 58
Nanjing Shizhou Biology Technology Co.,Ltd 025-85560043 15850508050 cindy.huang@synzest.com China 11975 58
Supplier Advantage
Shanghai Winherb Medical Technology Co., Ltd. 58
Shanghai EFE Biological Technology Co., Ltd. 58
Shanghai Hongye Biotechnology Co. Ltd 58
BOC Sciences 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Meng Cheng Technology (Shanghai) Co., LTD 58
Shanghai Moqi Biological Technology Co., LTD 58
Shanghai Yiyan Biotechnology Co. , Ltd. 58
Shanghai Saikerui Biotechnology Co. , Ltd. 58
Nanjing Shizhou Biology Technology Co.,Ltd 58

View Lastest Price from 2-(4-Hydroxybenzyl)-3-(4-hydroxyphenyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-2-carboxylic acid methyl ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Butyrolactone II pictures 2026-08-25 Butyrolactone II
87414-44-6
 $3.00-9.00 99% ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
  • Butyrolactone II pictures
  • Butyrolactone II
    87414-44-6
  • $3.00-9.00
  • 99%
  • ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

87414-44-6(2-(4-Hydroxybenzyl)-3-(4-hydroxyphenyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-2-carboxylic acid methyl ester)Related Search:

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2-(4-Hydroxybenzyl)-3-(4-hydroxyphenyl)-4-hydroxy-5-oxo-2,5-dihydrofuran-2-carboxylic acid methyl ester 2,5-Dihydro-2-(4-hydroxybenzyl)-3-(4-hydroxyphenyl)-4-hydroxy-5-oxo-2-furancarboxylic acid methyl ester 2,5-Dihydro-4-hydroxy-2-(4-hydroxybenzyl)-3-(4-hydroxyphenyl)-5-oxofuran-2-carboxylic acid methyl ester 2-Furancarboxylic acid, 2,5-dihydro-4-hydroxy-3-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-5-oxo-, methyl ester, (2R)- Butyrolactone II 87414-44-6 Antibiotic