ChemicalBook >> CAS DataBase List >>L-Leucine-2,3,3,4,5,5,5,6,6,6-d10

L-Leucine-2,3,3,4,5,5,5,6,6,6-d10

CAS No.
106972-44-5
Chemical Name:
L-Leucine-2,3,3,4,5,5,5,6,6,6-d10
Synonyms
L-Leucine-2,3,3,4,5,5,5,5′,5′,5′-d10;15N, 97%);D10-L-Leucine;L-LEUCINE-D10;l-leucine-c-d10;L-Leucine (D??, 98%);L-LEUCINE (D10, 98%);L-Leucine-d10 (Standard);L-Leucine-2,3,3,4,5,5,5,6,6,6-d10;L-Leucine-2,3,3,4,5,5,5,5′,5′,5′-d??
CBNumber:
CB5237298
Molecular Formula:
C6H3D10NO2
Molecular Weight:
141.23
MDL Number:
MFCD01321412
MOL File:
106972-44-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:53:23

L-Leucine-2,3,3,4,5,5,5,6,6,6-d10 Properties

Melting point >300 °C(lit.)
Boiling point 225.772±23.00 °C(Press: 760.00 Torr)(predicted)
Density 1.036±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
storage temp. Refrigerator
solubility Aqueous Acid (Slightly), Water (Slightly)
form Solid
pka 2.550±0.21(predicted)
color White to Off-White
optical activity [α]25/D +14.5°, c = 2 in 5 M HCl
InChI 1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1/i1D3,2D3,3D2,4D,5D
InChIKey ROHFNLRQFUQHCH-ZWFPVXGPSA-N
SMILES [2H]C([2H])([2H])C([2H])(C([2H])([2H])[2H])C([2H])([2H])[C@]([2H])(N)C(O)=O
UNSPSC Code 12352209
NACRES NA.12
CAS Number Unlabeled 61-90-5

SAFETY

Risk and Safety Statements

WGK Germany  3
Storage Class 11 - Combustible Solids

L-Leucine-2,3,3,4,5,5,5,6,6,6-d10 price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 492949 L-Leucine-2,3,3,4,5,5,5,5′,5′,5′-d10 98 atom % D 106972-44-5 250mg $636 2026-04-30 Buy
Cayman Chemical 34843 L-Leucine-d10 ≥99%deuteratedforms(d1-d10) 106972-44-5 5mg $81 2026-04-30 Buy
Cayman Chemical 34843 L-Leucine-d10 ≥99%deuteratedforms(d1-d10) 106972-44-5 10mg $152 2026-04-30 Buy
Cayman Chemical 34843 L-Leucine-d10 ≥99%deuteratedforms(d1-d10) 106972-44-5 25mg $317 2026-04-30 Buy
Cayman Chemical 34843 L-Leucine-d10 ≥99%deuteratedforms(d1-d10) 106972-44-5 50mg $475 2026-04-30 Buy
Product number Packaging Price Buy
492949 250mg $636 Buy
34843 5mg $81 Buy
34843 10mg $152 Buy
34843 25mg $317 Buy
34843 50mg $475 Buy

L-Leucine-2,3,3,4,5,5,5,6,6,6-d10 Chemical Properties, Uses, Production

Uses

L-Leucine-d10 is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].

References

[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Baoshan Xu, et al. Stimulation of mTORC1 with L-leucine rescues defects associated with Roberts syndrome. PLoS Genet. 2013;9(10):e1003857. DOI:10.1371/journal.pgen.1003857
[3] Bruckbauer A, et al. Synergistic effects of leucine and resveratrol on insulin sensitivity and fat metabolism in adipocytes and mice. Nutr Metab (Lond). 2012 Aug 22;9(1):77. DOI:10.1186/1743-7075-9-77
[4] Rachdi L, et al. L-leucine alters pancreatic β-cell differentiation and function via the mTor signaling pathway. Diabetes. 2012 Feb;61(2):409-17. DOI:10.2337/db11-0765

L-Leucine-2,3,3,4,5,5,5,6,6,6-d10 Preparation Products And Raw materials

Raw materials

Preparation Products

L-Leucine-2,3,3,4,5,5,5,6,6,6-d10 Suppliers

Global Suppliers ( 61)
Supplier Tel Email Country ProdList Advantage
Artis Chemistry (Shanghai) Co. Ltd. 86-21-60936353 China 335 58
Clearsynth Labs Limited +91-22-26355700 info@clearsynth.com India 9656 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
Nanjing Haolv Biotechnology Co.,Ltd 025-84622273 17361806303 kexin.zhou@haolvbiotech.com China 3009 58
Guangzhou Younan Technology Co., Ltd 020-82000279 18988941452 YN_research@163.com China 2984 58
Energy Chemical 400-0056266 marketing1@energy-chemical.com China 44927 58
Qingdao Tenglong microwave technology co., LTD. 0532-83818797 17669478191 sc@tlwb.com.cn China 3933 58
ChengDu SinoStandards Bio-Tech Co.,Ltd. , 028-83243028 19136088901 sinostandards@163.com China 4979 58
Manhag Testing Technology Co., Ltd 400-818 0104 18918165978 yanyan.guo@bestown.net.cn China 7770 58

View Latest Price from L-Leucine-2,3,3,4,5,5,5,6,6,6-d10 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
L-Leucine-D10 pictures 2026-07-15 L-Leucine-D10
106972-44-5
$170.00 10g TargetMol Chemicals Inc.
L-Leucine-d10 pictures 2025-11-05 L-Leucine-d10
106972-44-5
$1100.00-1200.00 1ton 99% 1000T/M Lianyungang Kaiyu Environmental Tech Co., Ltd.
  • L-Leucine-d10 pictures
  • L-Leucine-d10
    106972-44-5
  • $1100.00-1200.00
  • 99%
  • Lianyungang Kaiyu Environmental Tech Co., Ltd.
L-LEUCINE-2,3,3,4,5,5,5,6,6,6-D10, 98 AT OM % D l-leucine-c-d10 L-LEUCINE (D10, 98%) L-LEUCINE-D10 15N, 97%) L-Leucine-2,3,3,4,5,5,5,5',5',5'-d10 98 atom % D L-Leucine-2,3,3,4,5,5,5,5′,5′,5′-d?? L-Leucine-2,3,3,4,5,5,5,5′,5′,5′-d10 D10-L-Leucine L-Leucine (D??, 98%) microbiological/pyrogen tested L-Leucine (D??, 98%) L-Leucine-d10 (Standard) L-Leucine-2,3,3,4,5,5,5,5′,5′,5′-d10 L-Leucine-2,3,3,4,5,5,5,6,6,6-d10 106972-44-5 CD32CDCD2CDNH2COOH CD32CDCD2CDNH2CO2H Stable Isotopes BioChemical Alphabetical Listings