L-Leucine-2,3,3,4,5,5,5,6,6,6-d10
- CAS No.
- 106972-44-5
- Chemical Name:
- L-Leucine-2,3,3,4,5,5,5,6,6,6-d10
- Synonyms
- L-Leucine-2,3,3,4,5,5,5,5′,5′,5′-d10;15N, 97%);D10-L-Leucine;L-LEUCINE-D10;l-leucine-c-d10;L-Leucine (D??, 98%);L-LEUCINE (D10, 98%);L-Leucine-d10 (Standard);L-Leucine-2,3,3,4,5,5,5,6,6,6-d10;L-Leucine-2,3,3,4,5,5,5,5′,5′,5′-d??
- CBNumber:
- CB5237298
- Molecular Formula:
- C6H3D10NO2
- Molecular Weight:
- 141.23
- MDL Number:
- MFCD01321412
- MOL File:
- 106972-44-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | >300 °C(lit.) |
|---|---|
| Boiling point | 225.772±23.00 °C(Press: 760.00 Torr)(predicted) |
| Density | 1.036±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
| storage temp. | Refrigerator |
| solubility | Aqueous Acid (Slightly), Water (Slightly) |
| form | Solid |
| pka | 2.550±0.21(predicted) |
| color | White to Off-White |
| optical activity | [α]25/D +14.5°, c = 2 in 5 M HCl |
| InChI | 1S/C6H13NO2/c1-4(2)3-5(7)6(8)9/h4-5H,3,7H2,1-2H3,(H,8,9)/t5-/m0/s1/i1D3,2D3,3D2,4D,5D |
| InChIKey | ROHFNLRQFUQHCH-ZWFPVXGPSA-N |
| SMILES | [2H]C([2H])([2H])C([2H])(C([2H])([2H])[2H])C([2H])([2H])[C@]([2H])(N)C(O)=O |
| UNSPSC Code | 12352209 |
| NACRES | NA.12 |
| CAS Number Unlabeled | 61-90-5 |
L-Leucine-2,3,3,4,5,5,5,6,6,6-d10 price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 492949 | L-Leucine-2,3,3,4,5,5,5,5′,5′,5′-d10 98 atom % D | 106972-44-5 | 250mg | $636 | 2026-04-30 | Buy |
| Cayman Chemical | 34843 | L-Leucine-d10 ≥99%deuteratedforms(d1-d10) | 106972-44-5 | 5mg | $81 | 2026-04-30 | Buy |
| Cayman Chemical | 34843 | L-Leucine-d10 ≥99%deuteratedforms(d1-d10) | 106972-44-5 | 10mg | $152 | 2026-04-30 | Buy |
| Cayman Chemical | 34843 | L-Leucine-d10 ≥99%deuteratedforms(d1-d10) | 106972-44-5 | 25mg | $317 | 2026-04-30 | Buy |
| Cayman Chemical | 34843 | L-Leucine-d10 ≥99%deuteratedforms(d1-d10) | 106972-44-5 | 50mg | $475 | 2026-04-30 | Buy |
L-Leucine-2,3,3,4,5,5,5,6,6,6-d10 Chemical Properties, Uses, Production
Uses
L-Leucine-d10 is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].
References
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Baoshan Xu, et al. Stimulation of mTORC1 with L-leucine rescues defects associated with Roberts syndrome. PLoS Genet. 2013;9(10):e1003857. DOI:10.1371/journal.pgen.1003857
[3] Bruckbauer A, et al. Synergistic effects of leucine and resveratrol on insulin sensitivity and fat metabolism in adipocytes and mice. Nutr Metab (Lond). 2012 Aug 22;9(1):77. DOI:10.1186/1743-7075-9-77
[4] Rachdi L, et al. L-leucine alters pancreatic β-cell differentiation and function via the mTor signaling pathway. Diabetes. 2012 Feb;61(2):409-17. DOI:10.2337/db11-0765
L-Leucine-2,3,3,4,5,5,5,6,6,6-d10 Preparation Products And Raw materials
Raw materials
Preparation Products
L-Leucine-2,3,3,4,5,5,5,6,6,6-d10 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Artis Chemistry (Shanghai) Co. Ltd. | 86-21-60936353 | China | 335 | 58 | |
| Clearsynth Labs Limited | +91-22-26355700 | info@clearsynth.com | India | 9656 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51389 | 80 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Nanjing Haolv Biotechnology Co.,Ltd | 025-84622273 17361806303 | kexin.zhou@haolvbiotech.com | China | 3009 | 58 |
| Guangzhou Younan Technology Co., Ltd | 020-82000279 18988941452 | YN_research@163.com | China | 2984 | 58 |
| Energy Chemical | 400-0056266 | marketing1@energy-chemical.com | China | 44927 | 58 |
| Qingdao Tenglong microwave technology co., LTD. | 0532-83818797 17669478191 | sc@tlwb.com.cn | China | 3933 | 58 |
| ChengDu SinoStandards Bio-Tech Co.,Ltd. , | 028-83243028 19136088901 | sinostandards@163.com | China | 4979 | 58 |
| Manhag Testing Technology Co., Ltd | 400-818 0104 18918165978 | yanyan.guo@bestown.net.cn | China | 7770 | 58 |
View Latest Price from L-Leucine-2,3,3,4,5,5,5,6,6,6-d10 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-07-15 | L-Leucine-D10
106972-44-5
|
$170.00 | 10g | TargetMol Chemicals Inc. | |||
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2025-11-05 | L-Leucine-d10
106972-44-5
|
$1100.00-1200.00 | 1ton | 99% | 1000T/M | Lianyungang Kaiyu Environmental Tech Co., Ltd. |
-

- L-Leucine-D10
106972-44-5
- $170.00
- TargetMol Chemicals Inc.
-

- L-Leucine-d10
106972-44-5
- $1100.00-1200.00
- 99%
- Lianyungang Kaiyu Environmental Tech Co., Ltd.




