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1,14-diamino-3,6,9,12-tetraoxatetradecane

1,14-diamino-3,6,9,12-tetraoxatetradecane structure

CAS No.: 68960-97-4

Chemical Name:: 1,14-diamino-3,6,9,12-tetraoxatetradecane

Synonyms: NH2-PEG4-NH2;3,6,9,12-Tetraoxatetradecane-1,14-diaMine;Amino-PEG4-Amine;mino-PEG4-Amine;Amine-PEG4-amine;Amino-dPEG4-Amino;Amino-PEG4-Amine,NH2-PEG4-NH2;Aminopentapolyethylene glycol amine;1,14-diamino-3,6,9,12-tetraoxatetradecane;Triethylene Glycol Bis(2-aminoethyl) Ether

CBNumber:: CB52469749

Molecular Formula:: C10H24N2O4

Molecular Weight:: 236.31

MDL Number:: MFCD01365938

MOL File:: 68960-97-4.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-16 07:06:08

Product description	Number	Pack Size	Price
NH2-PEG4-NH2	JKA12010	500MG	$345
1,14-Diamino-3,6,9,12-tetraoxatetradecane >97.0%(GC)	T3198	100mg	$112
Amine-PEG4-Amine (3,6,9,12-Tetraoxatetradecane-1,14-diamine) ≥95%	516917	5g	$708
H2N-PEG4-CH2CH2NH2	281705-5G	5g	$768
H2N-PEG4-CH2CH2NH2	281705-1G	1g	$309
More product size

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1,14-diamino-3,6,9,12-tetraoxatetradecane Properties

Boiling point	139°C/0.2mmHg(lit.)
Density	1.043±0.06 g/cm3(Predicted)
refractive index	1.4650 to 1.4690
storage temp.	-20°C
solubility	Soluble in Water, DMSO, DCM, DMF
pka	9.04±0.10(Predicted)
form	clear liquid
color	Colorless to Light yellow
InChI	InChI=1S/C10H24N2O4/c11-1-3-13-5-7-15-9-10-16-8-6-14-4-2-12/h1-12H2
InChIKey	IFZOPNLVYZYSMQ-UHFFFAOYSA-N
SMILES	C(N)COCCOCCOCCOCCN
UNSPSC Code	51171641
NACRES	NA.23

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319

Precautionary statements

P301+P312+P330-P305+P351+P338

RIDADR

UN 2735 8/PG III

WGK Germany

WGK 3

HazardClass

PackingGroup

III

HS Code

2942000090

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2

NFPA 704

	1
3		0

1,14-diamino-3,6,9,12-tetraoxatetradecane price More Price(88)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	JKA12010	NH2-PEG4-NH2	68960-97-4	500MG	$345	2026-04-30	Buy
TCI Chemical	T3198	1,14-Diamino-3,6,9,12-tetraoxatetradecane >97.0%(GC)	68960-97-4	100mg	$112	2026-04-30	Buy
Usbiological	516917	Amine-PEG4-Amine (3,6,9,12-Tetraoxatetradecane-1,14-diamine) ≥95%	68960-97-4	5g	$708	2026-06-03	Buy
ChemPep	281705-5G	H2N-PEG4-CH2CH2NH2	68960-97-4	5g	$768	2026-06-04	Buy
ChemPep	281705-1G	H2N-PEG4-CH2CH2NH2	68960-97-4	1g	$309	2026-06-04	Buy

Product number	Packaging	Price	Buy
JKA12010	500MG	$345	Buy
T3198	100mg	$112	Buy
516917	5g	$708	Buy
281705-5G	5g	$768	Buy
281705-1G	1g	$309	Buy

1,14-diamino-3,6,9,12-tetraoxatetradecane Chemical Properties,Uses,Production

Description

Amino-PEG4-Amine is a very useful crosslinker containing two amino groups. The amino groups are reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc.

Uses

Applications may include: bioconjugation, drug delivery, PEG hydrogel, crosslinker, and surface functionalization

Synthesis

109789-39-1

1,14-diamino-3,6,9,12-tetraoxatetradecane

68960-97-4

The general procedure for the synthesis of 3,6,9,12-tetraoxatetradecane-1,14-diamine from the compound (CAS:109789-39-1) is as follows: 9.1 mmol of methanesulfonyloxy-diethyleneglycol-methanesulfonate (MsO-PEG2-OMs) was dissolved in an appropriate amount of dichloromethane. To this solution, excess ammonia and 2 mmol of tetrabutylammonium bromide were added as a phase transfer catalyst, followed by stirring the reaction at 45 °C for 12 hours. Upon completion of the reaction, the solvent was removed by rotary evaporator and then purified by distillation under reduced pressure to afford the target product 3,6,9,12-tetraoxatetradecane-1,14-diamine (NH2-PEG4-NH2) in a yield of 7.64 mmol and 84%.

IC 50

PEGs

References

[1] Patent: CN107840817, 2018, A. Location in patent: Paragraph 0050; 0052
[2] Inorganic Chemistry, 2015, vol. 54, # 14, p. 6807 - 6820
[3] Journal of Polymer Science, Part A: Polymer Chemistry, 2016, vol. 54, # 20, p. 3294 - 3302

1,14-diamino-3,6,9,12-tetraoxatetradecane Preparation Products And Raw materials

Raw materials

Pentaethylene Glycol Dimethanesulfonate Dichloromethane TETRABUTYLAMMOMIUM BROMIDE Ammonium hydroxide

Preparation Products

1,14-diamino-3,6,9,12-tetraoxatetradecane Suppliers

Global( 140)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	+86-15225627621 +86-13213167925	jiuyitime@fdachem.com	China	16511	58
9i LLC	+18039569191	MWan@NiNeiLab.com	United States	418	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29812	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	21193	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	+86-021-61551413 +8618813727289	contact@trustwe.com	China	5746	58
TargetMol Chemicals Inc.	+1-781-999-5354; +17819995354	marketing@targetmol.com	United States	32466	58
Wuhan Borenpharm Co., Ltd	027-65563561 18717150066	3207347307@qq.com	CHINA	1238	58
XIAMEN SINOPEG BIOTECH CO., LTD.	+86-0592-7761068 +8617350879715	changaiwei@sinopeg.com	China	1125	58
Shaanxi Youbang Biopharma Technology Co.,Ltd.	+86-0913-7167565 +8618754046789	316745545@qq.com	China	86	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19908	58

Supplier	Advantage
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD	58
9i LLC	58
career henan chemical co	58
Accela ChemBio Inc.	58
SHANGHAI T&W PHARMACEUTICAL CO., LTD.	58
TargetMol Chemicals Inc.	58
Wuhan Borenpharm Co., Ltd	58
XIAMEN SINOPEG BIOTECH CO., LTD.	58
Shaanxi Youbang Biopharma Technology Co.,Ltd.	58
Nextpeptide Inc	58

View Lastest Price from 1,14-diamino-3,6,9,12-tetraoxatetradecane manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-07-24	3,6,9,12-tetraoxatetradecane-1,14-diamine 68960-97-4		1g	98%	68960-97-4	XIAMEN SINOPEG BIOTECH CO., LTD.
2026-07-15	Amino-PEG4-C2-amine 68960-97-4				10g	TargetMol Chemicals Inc.
2026-07-02	Amino-PEG4-C2-amine 68960-97-4	$2.00-6.00	1kg	99%	100kg	ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

3,6,9,12-tetraoxatetradecane-1,14-diamine
68960-97-4
98%
XIAMEN SINOPEG BIOTECH CO., LTD.

Amino-PEG4-C2-amine
68960-97-4
$0.00
TargetMol Chemicals Inc.

Amino-PEG4-C2-amine
68960-97-4
$2.00-6.00
99%
ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

1,14-diamino-3,6,9,12-tetraoxatetradecane Spectrum

1,14-diamino-3,6,9,12-tetraoxatetradecane(68960-97-4)¹HNMR

68960-97-4(1,14-diamino-3,6,9,12-tetraoxatetradecane)Related Search:

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2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethanamine Amino-dPEG4-Amino 1,14-diamino-3,6,9,12-tetraoxatetradecane Amino-PEG4-Amine,NH2-PEG4-NH2 mino-PEG4-Amine Triethylene Glycol Bis(2-aminoethyl) Ether Aminopentapolyethylene glycol amine 3,6,9,12-Tetraoxatetradecane-1,14-diaMine Amino-PEG4-Amine NH2-PEG4-NH2 Amine-PEG4-amine 68960-97-4 PROTAC LINKER peg