Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>(4-CHLOROPHENYL)(PIPERAZIN-1-YL) METHANONE

(4-CHLOROPHENYL)(PIPERAZIN-1-YL) METHANONE

(4-CHLOROPHENYL)(PIPERAZIN-1-YL) METHANONE Structure
(4-CHLOROPHENYL)(PIPERAZIN-1-YL) METHANONE structure
CAS No.
54042-47-6
Chemical Name:
(4-CHLOROPHENYL)(PIPERAZIN-1-YL) METHANONE
Synonyms
1-(4-CHLOROBENZOYL)PIPERAZINE;Methanone, (4-chlorophenyl)-1-piperazinyl-;(4-CHLOROPHENYL)(PIPERAZIN-1-YL) METHANONE
CBNumber:
CB5253201
Molecular Formula:
C11H13ClN2O
Molecular Weight:
224.69
MDL Number:
MFCD01050442
MOL File:
54042-47-6.mol
MSDS File:
SDS
Last updated:2026-05-28 02:36:51
Product description Number Pack Size Price
(4-Chlorophenyl)(piperazin-1-yl)methanone 95% AS114920 1g $156
(4-Chlorophenyl)(piperazin-1-yl)methanone 95% AS114920 5g $489
(4-Chlorophenyl)(piperazin-1-yl)methanone 305232 1.00g $115
(4-Chlorophenyl)(piperazin-1-yl)methanone 305232 5.00g $361
(4-Chlorophenyl)(piperazin-1-yl)methanone 305232 25.00g $994
Request For Quotation

(4-CHLOROPHENYL)(PIPERAZIN-1-YL) METHANONE Properties

Melting point 200 °C
Boiling point 384.0±37.0 °C(Predicted)
Density 1.231±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka 8.32±0.10(Predicted)
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H335-H319-H302
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501
Hazard Codes  Xn
Risk Statements  22-36

(4-CHLOROPHENYL)(PIPERAZIN-1-YL) METHANONE price More Price(53)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS114920 (4-Chlorophenyl)(piperazin-1-yl)methanone 95% 54042-47-6 1g $156 2026-06-04 Buy
Activate Scientific AS114920 (4-Chlorophenyl)(piperazin-1-yl)methanone 95% 54042-47-6 5g $489 2026-06-04 Buy
Matrix Scientific 305232 (4-Chlorophenyl)(piperazin-1-yl)methanone 54042-47-6 1.00g $115 2026-05-19 Buy
Matrix Scientific 305232 (4-Chlorophenyl)(piperazin-1-yl)methanone 54042-47-6 5.00g $361 2026-05-19 Buy
Matrix Scientific 305232 (4-Chlorophenyl)(piperazin-1-yl)methanone 54042-47-6 25.00g $994 2026-05-19 Buy
Product number Packaging Price Buy
AS114920 1g $156 Buy
AS114920 5g $489 Buy
305232 1.00g $115 Buy
305232 5.00g $361 Buy
305232 25.00g $994 Buy

(4-CHLOROPHENYL)(PIPERAZIN-1-YL) METHANONE Chemical Properties,Uses,Production

Synthesis

tert-Butyl 4-(4-chlorobenzoyl)piperazine-1-carboxylate

897445-35-1

(4-CHLOROPHENYL)(PIPERAZIN-1-YL) METHANONE

54042-47-6

Step 2: Synthesis of (4-chlorophenyl)(piperazin-1-yl)methanone (C) Dissolve tert-butyl 4-(4-chlorobenzoyl)piperazine-1-carboxylate (26 g) in dichloromethane (350 mL). To the solution was added 4 M hydrochloric acid/dioxane solution (150 mL). The reaction mixture was stirred at room temperature for 4 hours, during which time the formation of a white precipitate was observed. Upon completion of the reaction, the mixture was concentrated to remove the solvent. The resulting white solid was washed with ether. Subsequently, the white solid was treated with 1 N sodium hydroxide solution (200 mL) and extracted with ethyl acetate (3 x 100 mL). The organic phases were combined, dried over anhydrous sodium sulfate and concentrated to give the target product (4-chlorophenyl)(piperazin-1-yl)methanone (17.79 g, 99% yield). Product characterization data: 1H-NMR (hydrochloride, 300 MHz, MeOD): δ 2.80-2.90 (m, 4H), 3.20-3.80 (m, 4H), 7.29-7.36 (m, 4H).

References

[1] Patent: WO2006/71875, 2006, A1. Location in patent: Page/Page column 78
[2] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 2, p. 1139 - 1148
[3] Bioorganic and Medicinal Chemistry Letters, 2014, vol. 24, # 16, p. 3739 - 3743
[4] Archiv der Pharmazie, 2017, vol. 350, # 8,
[5] Patent: CN107226807, 2017, A. Location in patent: Paragraph 0546-0548

(4-CHLOROPHENYL)(PIPERAZIN-1-YL) METHANONE synthesis

897445-35-1
54042-47-6
Synthesis of (4-CHLOROPHENYL)(PIPERAZIN-1-YL) METHANONE from tert-Butyl 4-(4-chlorobenzoyl)piperazine-1-carboxylate

(4-CHLOROPHENYL)(PIPERAZIN-1-YL) METHANONE Preparation Products And Raw materials

Raw materials

tert-Butyl 4-(4-chlorobenzoyl)piperazine-1-carboxylate Sodium hydroxide Hydrochloric acid 1,4-Dioxane Dichloromethane

Preparation Products

(4-CHLOROPHENYL)(PIPERAZIN-1-YL) METHANONE Suppliers

Global( 41)Suppliers
Supplier Tel Email Country ProdList Advantage
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30224 58
CR Corporation Limited 		+8613062833949 fred.wen@crcorporation.cn China 8645 58
Aladdin Scientific 		tp@aladdinsci.com United States 57505 58
DAYANG CHEM (HANGZHOU) CO.,LTD 		+86-88938639 +86-17705817739 info@dycnchem.com China 53803 58
Zhengzhou Guancheng Laboratory equipment Sales 0371-88888888 272369594 2723695949@qq.com China 4995 50
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 89686 60
Yantai ShengKailun Chemical Technology Co., Ltd. 13356901049 3119594100@qq.com China 7964 55
Amatek Scientific Co. Ltd. 0512-56316828 info@amateksci.com China 28769 58
Hangzhou Molcore Biopharmatech Co.,Ltd 400-711-5280 86-571-81025280 sales@molcore.com China 9967 58
Aikon International Limited 025-58851090 15955137747 sales01@aikonchem.com China 15949 58
Supplier Advantage
Career Henan Chemica Co 		58
CR Corporation Limited 		58
Aladdin Scientific 		58
DAYANG CHEM (HANGZHOU) CO.,LTD 		58
Zhengzhou Guancheng Laboratory equipment Sales 50
Shanghai YuanYe Biotechnology Co., Ltd. 60
Yantai ShengKailun Chemical Technology Co., Ltd. 55
Amatek Scientific Co. Ltd. 58
Hangzhou Molcore Biopharmatech Co.,Ltd 58
Aikon International Limited 58

(4-CHLOROPHENYL)(PIPERAZIN-1-YL) METHANONE Spectrum

(4-CHLOROPHENYL)(PIPERAZIN-1-YL) METHANONE(54042-47-6)1HNMR

54042-47-6((4-CHLOROPHENYL)(PIPERAZIN-1-YL) METHANONE)Related Search:

CPNQ (4-CHLOROPHENYL)(PIPERAZIN-1-YL) METHANONE ETHYL 2-[1-(2,4-DICHLOROBENZOYL)-3-OXO-2-PIPERAZINYL]ACETATE 4-[4-(2,4-DICHLOROBENZOYL)PIPERAZINO]-3-NITROBENZENECARBALDEHYDE O-METHYLOXIME (4-BENZOYLPIPERAZINO)(2,4-DICHLOROPHENYL)METHANONE
ETHYL 2-[1-(3,4-DICHLOROBENZOYL)-3-OXO-2-PIPERAZINYL]ACETATE 2,4-DICHLOROPHENYL 4-(5-CHLORO-2-METHYLPHENYL)PIPERAZINYL KETONE 5-[4-(4-CHLOROBENZOYL)PIPERAZINO]-6-PHENYL-3(2H)-PYRIDAZINONE BUTTPARK 39\04-51 ETHYL 2-[1-(4-CHLOROBENZOYL)-3-OXO-2-PIPERAZINYL]ACETATE
(4-CHLOROPHENYL)(4-(4,6-DI(PIPERIDIN-1-YL)-1,3,5-TRIAZIN-2-YL)PIPERAZIN-1-YL)METHANONE (4-CHLOROPHENYL)[4-(3-CHLOROQUINOXALIN-2-YL)PIPERAZINO]METHANONE METHYL 4-[4-(3,4-DICHLOROBENZOYL)PIPERAZINO]-3-NITROBENZENECARBOXYLATE 4-[4-(4-CHLOROBENZOYL)PIPERAZINO]BENZENECARBONITRILE 1-(p-Chlorobenzoyl)-4-isobutylpiperazine hydrochloride
[4-(1,3-BENZOTHIAZOL-2-YL)PIPERAZINO](4-CHLOROPHENYL)METHANONE (4-CHLOROPHENYL)[4-(6-CHLORO-2-PYRIDINYL)PIPERAZINO]METHANONE 1-(4-chlorobenzoyl)piperazine-2,3-dicarboxylic acid

1of4

(4-CHLOROPHENYL)(PIPERAZIN-1-YL) METHANONE 1-(4-CHLOROBENZOYL)PIPERAZINE Methanone, (4-chlorophenyl)-1-piperazinyl- 54042-47-6