Methyl 2-(5-broMopyridin-2-yl)acetate
- CAS No.
- 917023-06-4
- Chemical Name:
- Methyl 2-(5-broMopyridin-2-yl)acetate
- Synonyms
- Methyl 5-broMopyridine-2-acetate;Methyl 2-(5-bromo-2-pyridyl)acetate;Methyl 2-(5-broMopyridin-2-yl)acetate;(5-BroMo-2-pyridinyl)acetic acid Methyl ester;2-Pyridineacetic acid, 5-bromo-, methyl ester
- CBNumber:
- CB52563337
- Molecular Formula:
- C8H8BrNO2
- Molecular Weight:
- 230.06
- MDL Number:
- MFCD12031821
- MOL File:
- 917023-06-4.mol
- MSDS File:
- SDS
| Boiling point | 266.0±25.0 °C(Predicted) |
|---|---|
| Density | 1.517±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| form | solid |
| pka | 1.95±0.22(Predicted) |
| Appearance | White to yellow Solid |
| InChI | InChI=1S/C8H8BrNO2/c1-12-8(11)4-7-3-2-6(9)5-10-7/h2-3,5H,4H2,1H3 |
| InChIKey | NIAATLPQSKGUBG-UHFFFAOYSA-N |
| SMILES | C1(CC(OC)=O)=NC=C(Br)C=C1 |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral |
Methyl 2-(5-broMopyridin-2-yl)acetate price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHB00159 | Methyl 5-bromopyridine-2-acetate AldrichCPR | 1 g | $191 | 2026-04-30 | Buy | |
| Matrix Scientific | 207596 | Methyl 2-(5-bromo-2-pyridyl)acetate | 917023-06-4 | 5.00g | $568 | 2026-05-18 | Buy |
| Synthonix | M10106 | Methyl 2-(5-bromopyridin-2-yl)acetate 97% | 917023-06-4 | 250mg | $79 | 2026-05-06 | Buy |
| Synthonix | M10106 | Methyl 2-(5-bromopyridin-2-yl)acetate 97% | 917023-06-4 | 1g | $93 | 2026-05-06 | Buy |
| Synthonix | M10106 | Methyl 2-(5-bromopyridin-2-yl)acetate 97% | 917023-06-4 | 5g | $97 | 2026-05-06 | Buy |
Methyl 2-(5-broMopyridin-2-yl)acetate Chemical Properties, Uses, Production
Synthesis
192642-83-4
18107-18-1
917023-06-4
5-(5-Bromo-1H-2-pyridinyl)-2,2-dimethyl-[1,3]dioxane-4,6-dione (4.53 g, 15.09 mmol) was used as a starting material and dissolved in dioxane (20 mL). Concentrated hydrochloric acid (10 mL) was added to this solution and the mixture was subsequently stirred at 100 °C for 1 hour. Upon completion of the reaction, the mixture was cooled and concentrated under reduced pressure. The concentrated residue was dissolved in a solvent mixture of methanol (20 mL) and toluene (20 mL). To this solution was added trimethylsilylated diazomethane (2M ethyl ether solution, 25 mL) and stirred for 30 minutes at room temperature. Reaction termination was achieved by addition of acetic acid. Subsequently, the reaction mixture was concentrated under reduced pressure. The residue was purified by silica gel column chromatography (eluent: hexane/ethyl acetate = 100:0 to 30:70, 40 min) to afford the target product methyl 2-(5-bromopyridin-2-yl)acetate as a colorless oil (2.50 g, 72% yield). The product was characterized by 1H-NMR (chloroform-d): δ 3.73 (3H, s), 3.82 (2H, s), 7.21 (1H, d, J=8.24 Hz), 7.79 (1H, dd, J=8.25,2.31 Hz), 8.62 (1H, d, J=2.31 Hz).
References
[1] Patent: EP1894911, 2008, A1. Location in patent: Page/Page column 82
Methyl 2-(5-broMopyridin-2-yl)acetate Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Methyl 2-(5-broMopyridin-2-yl)acetate Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Sealing Biotechnology Co. Ltd.. | 15721176654;15710104046 | 1815535157@qq.com | China | 984 | 58 |
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View Latest Price from Methyl 2-(5-broMopyridin-2-yl)acetate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-10 | Methyl 2-(5-bromopyridin-2-yl)acetate
917023-06-4
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- Methyl 2-(5-bromopyridin-2-yl)acetate
917023-06-4
- $1.00
- 99%
- Career Henan Chemical Co
