METHYL 4-IODO-3-NITROBENZOATE
- CAS No.
- 89976-27-2
- Chemical Name:
- METHYL 4-IODO-3-NITROBENZOATE
- Synonyms
- METHYL 4-IODO-3-NITROBENZOATE;4-iodo-3-nitrobenzoic acid methyl ester;Benzoic acid, 4-iodo-3-nitro-, methyl ester;Methyl-4-iodo-3-nitrobenzoate SynonyMs 4-Iodo-3-Nitrobenzoic Acid Methyl Ester
- CBNumber:
- CB5256646
- Molecular Formula:
- C8H6INO4
- Molecular Weight:
- 307.04
- MDL Number:
- MFCD08064223
- MOL File:
- 89976-27-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Methyl 4-iodo-3-nitrobenzoate 98% | OR400138 | 1g | $21 |
| Methyl 4-iodo-3-nitrobenzoate 98% | OR400138 | 5g | $24 |
| Methyl 4-iodo-3-nitrobenzoate 98% | OR400138 | 25g | $40 |
| Methyl 4-iodo-3-nitrobenzoate 98% | OR400138 | 100g | $150 |
| Methyl 4-iodo-3-nitrobenzoate 98% | OR400138 | 500g | $717 |
| Melting point | 103-105°C |
|---|---|
| Boiling point | 360.1±32.0 °C(Predicted) |
| Density | 1.904±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C(protect from light) |
| Appearance | Yellow to brown Solid |
| Water Solubility | Soluble in DCM 10mg/0.5mL. Insoluble in water. |
| Sensitive | Light Sensitive |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Risk Statements | 20/21/22-36/37/38 | |||||||||
| Safety Statements | 26-37/39 | |||||||||
| HS Code | 2916399090 | |||||||||
| NFPA 704 |
|
METHYL 4-IODO-3-NITROBENZOATE price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR400138 | Methyl 4-iodo-3-nitrobenzoate 98% | 89976-27-2 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR400138 | Methyl 4-iodo-3-nitrobenzoate 98% | 89976-27-2 | 5g | $24 | 2026-06-04 | Buy |
| Apolloscientific | OR400138 | Methyl 4-iodo-3-nitrobenzoate 98% | 89976-27-2 | 25g | $40 | 2026-06-04 | Buy |
| Apolloscientific | OR400138 | Methyl 4-iodo-3-nitrobenzoate 98% | 89976-27-2 | 100g | $150 | 2026-06-04 | Buy |
| Apolloscientific | OR400138 | Methyl 4-iodo-3-nitrobenzoate 98% | 89976-27-2 | 500g | $717 | 2026-06-04 | Buy |
METHYL 4-IODO-3-NITROBENZOATE Chemical Properties,Uses,Production
Uses
Methyl 4-iodo-3-nitrobenzoate is used as pharmaceutical intermediate.
Synthesis
67-56-1
35674-27-2
89976-27-2
Example 1: General procedure for the preparation of methyl 4-iodo-3-nitrobenzoate using methanol/sulfuric acid 1. dissolve 4-iodo-3-nitrobenzoic acid (3 g, 10 mmol) in methanol (30 ml) and cool the solution to 0°C. 2. sulfuric acid (3.4 g, 34.6 mmol) was added slowly to the above cooled solution. 3. the reaction mixture was gradually warmed to room temperature and subsequently heated to reflux (about 70 °C) and maintained for 8 hours. 4. Upon completion of the reaction, the reaction mixture was cooled and neutralized to pH neutral with solid NaHCO3 and filtered to remove the resulting salt. 5. The filtrate was concentrated under pressure to give a crude product. 6. Water (30 ml) was added to the crude product and extracted with methyl tertiary butyl ether (MTBE, 30 ml x 2). 7. The organic phases were combined, washed with saturated brine, dried over anhydrous sodium sulfate and filtered. 8. The solvent was evaporated under pressure to give methyl 4-iodo-3-nitrobenzoate as a yellow solid (2.67 g, 85% yield, 98% HPLC purity).
References
[1] Dalton Transactions, 2015, vol. 44, # 5, p. 2047 - 2051
[2] Chemical Communications, 2017, vol. 53, # 55, p. 7808 - 7811
[3] Patent: US2013/172618, 2013, A1. Location in patent: Paragraph 0025
[4] Patent: WO2017/48954, 2017, A1. Location in patent: Paragraph 00095
[5] Patent: WO2005/40157, 2005, A2. Location in patent: Page/Page column 68
METHYL 4-IODO-3-NITROBENZOATE Preparation Products And Raw materials
Raw materials
Preparation Products
METHYL 4-IODO-3-NITROBENZOATE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Fuxin Pharmaceutical | +86-021-021-50872116 | contact@fuxinpharm.com | China | 9976 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 | marketing1@neostarunited.com | China | 8827 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14301 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +86-15355479329 | market18@leapchem.com | China | 43303 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 50108 | 58 | |
| Suzhou ARTK Medchem Co., Ltd. | +86-18168183658 | sales1@artkmedchem.com | China | 39007 | 58 |
| Shaanxi Dideu New Materials Co. Ltd | 18192503167 | 1036@dideu.com | China | 13339 | 58 |
| XIAMEN AMITY INDUSTRY AND TRADE CO., LTD. | +8618950047208 | ellena@amitychem.com | China | 43392 | 58 |
View Lastest Price from METHYL 4-IODO-3-NITROBENZOATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-30 | METHYL 4-IODO-3-NITROBENZOATE
89976-27-2
|
1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd |
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- METHYL 4-IODO-3-NITROBENZOATE
89976-27-2
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
