ChemicalBook >> CAS DataBase List >>Trimethyl orthoacetate
Trimethyl orthoacetate
- CAS No.
- 1445-45-0
- Chemical Name:
- Trimethyl orthoacetate
- Synonyms
- TMOA;1,1,1-TRIMETHOXYETHANE;CH3C(OCH3)3;orthoacetate;Ethane, 1,1,1-trimethoxy-;Methyl orthoacetate;Trimethylorthoaceate;Trimethylorthoacetat;trimethyl-acetate;Trimethyl o-acetate
- CBNumber:
- CB5759743
- Molecular Formula:
- C5H12O3
- Molecular Weight:
- 120.15
- MDL Number:
- MFCD00008477
- MOL File:
- 1445-45-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-28 02:33:18
| Product description | Number | Pack Size | Price |
| Trimethyl orthoacetate for synthesis | 8.18804 | 100mL | $71 |
| Trimethyl orthoacetate for synthesis | 8.18804 | 500mL | $157 |
| Trimethyl orthoacetate 99% | 237876 | 100ml | $64.4 |
| Trimethyl orthoacetate 99% | 237876 | 500ml | $201 |
| Trimethyl Orthoacetate >98.0%(GC) | O0115 | 25mL | $30 |
| More product size | |||
| Boiling point | 107-109 °C(lit.) |
|---|---|
| Density | 0.944 g/mL at 25 °C(lit.) |
| vapor pressure | 20 hPa (20 °C) |
| refractive index |
n |
| Flash point | 62 °F |
| storage temp. | Store below +30°C. |
| solubility | Chloroform (Sparingly), Methanol (Slightly) |
| form | Liquid |
| color | Clear colorless to slightly brown |
| Specific Gravity | 0.960 (20/4℃) |
| Water Solubility | HYDROLYSIS |
| Sensitive | Moisture Sensitive |
| BRN | 1098338 |
| Henry's Law Constant | 6.4×10-1 mol/(m3Pa) at 25℃, Guthrie (1973) |
| InChI | 1S/C5H12O3/c1-5(6-2,7-3)8-4/h1-4H3 |
| InChIKey | HDPNBNXLBDFELL-UHFFFAOYSA-N |
| SMILES | COC(C)(OC)OC |
| LogP | 1.13 at 25℃ |
| CAS DataBase Reference | 1445-45-0(CAS DataBase Reference) |
| FDA UNII | 04H7A3FK37 |
| NIST Chemistry Reference | Ethane, 1,1,1-trimethoxy-(1445-45-0) |
| EPA Substance Registry System | Trimethyl orthoacetate (1445-45-0) |
| UNSPSC Code | 12352112 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H315-H319-H225 | |||||||||
| Precautionary statements | P501-P240-P210-P233-P243-P241-P242-P264-P280-P370+P378-P337+P313-P305+P351+P338-P362+P364-P303+P361+P353-P332+P313-P403+P235 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | F,Xi | |||||||||
| Risk Statements | 11-43-38-36/37/38 | |||||||||
| Safety Statements | 16-37/39-24-33-26-7/9 | |||||||||
| RIDADR | UN 3272 3/PG 2 | |||||||||
| WGK Germany | 1 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 3 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29159080 | |||||||||
| Storage Class | 3 - Flammable liquids | |||||||||
| Hazard Classifications | Eye Irrit. 2 Flam. Liq. 2 Skin Sens. 1B |
|||||||||
| Toxicity | LD50 orally in Rabbit: > 2000 mg/kg | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
Trimethyl orthoacetate price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.18804 | Trimethyl orthoacetate for synthesis | 1445-45-0 | 100mL | $71 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.18804 | Trimethyl orthoacetate for synthesis | 1445-45-0 | 500mL | $157 | 2026-04-30 | Buy |
| Sigma-Aldrich | 237876 | Trimethyl orthoacetate 99% | 1445-45-0 | 100ml | $64.4 | 2026-04-30 | Buy |
| Sigma-Aldrich | 237876 | Trimethyl orthoacetate 99% | 1445-45-0 | 500ml | $201 | 2026-04-30 | Buy |
| TCI Chemical | O0115 | Trimethyl Orthoacetate >98.0%(GC) | 1445-45-0 | 25mL | $30 | 2026-04-30 | Buy |
Trimethyl orthoacetate Chemical Properties,Uses,Production
Chemical Properties
CLEAR COLOURLESS TO SLIGHTLY BROWN LIQUID
Uses
Trimethyl orthoacetate has been used in the preparation of 2-amino-9-(3-acyloxymethyl-4-alkoxycarbonyloxybut-1-yl)purines and 2-amino-9-(3-alkoxycarbonyl-oxymethyl-4-alkoxycarbonyloxybut -1-yl)purines.
General Description
Kinetics and mechanism of gas-phase elimination of trimethyl orthoacetate has been examined over the temperature range of 310-369°C and pressure range of 50-130Torr.
Toxics Screening Level
The ITSL of Trimethyl orthoacetate is 24 μg/m3 with annual averaging.
Trimethyl orthoacetate Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
Methyl 3,3-dimethylpent-4-enoate
Methyl N-cyanoethanimideate
Triethyl orthoacetate
4,6-Dimethylpyrimidine-5-carboxylic acid
N-TERT-BUTYLACETAMIDE
1of3
Global( 412)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-86-13131129325 +8613131129325 | sales1@chuanghaibio.com | China | 5220 | 58 |
| Chongqing Soarwin Technology Co., Ltd | +86-15790943001 | crystal@sorawin.cn | China | 421 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Hangzhou Bayee Chemical Co., Ltd. | 0086-571-86990109 | rachelhoo@bayeechem.com | China | 104 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21585 | 55 |
| Shanxi Naipu Import and Export Co.,Ltd | +86-13734021967 +8613734021967 | kaia@neputrading.com | China | 1001 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2950 | 58 |
Related articles
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- Oct 23，2019
View Lastest Price from Trimethyl orthoacetate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-05-28 | Trimethyl Orthoacetate
1445-45-0
|
$5.70 | 10KG | 99% | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD | |
 |
2026-03-20 | Trimethyl orthoacetate
1445-45-0
|
$10.00 | 1kg | 99% | 100 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2025-08-20 | Trimethyl Orthoacetate
1445-45-0
|
1kg | 99.99% | 20 tons | Chongqing Soarwin Technology Co., Ltd |
-
- Trimethyl Orthoacetate
1445-45-0
- $5.70
- 99%
- Hebei Chuanghai Biotechnology Co,.LTD
-
- Trimethyl orthoacetate
1445-45-0
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Trimethyl Orthoacetate
1445-45-0
- 99.99%
- Chongqing Soarwin Technology Co., Ltd
1445-45-0(Trimethyl orthoacetate)Related Search:
Methyl trifluoroacetate
Methyl chloroacetate
Trimethyl phosphonoacetate
Trimethyl phosphate
Methyl cyanoacetate
Methyl 2,2-dimethylphenylacetate
Benzyl acetate
Methyl bromoacetate
Trimethyl borate
Triethyl orthopropionate
1of4
1,1,1-trimethoxy-ethan
Methyl orthoacetate
trimethyl-acetate
Trimethylorthoaceate
ORTHOACETIC ACID TRIMETHYL ESTER
TRIMETHYL ORTHOACETATE
1,1,1-Trimethoxyethane
Orthoacetic Acid Trimethyl Ester
Methylorthoformic acid trimethyl ester
Trimethyl orthoacetate,98%
Orthoacetic Acid Trimethyl Ester
1,1,1-Trimethoxyethane
The originalacetic acidtriMethyl ester
The original three Methyl acetate
Trimethyl o-acetate
TrimethoxyOrthoAcetate
Trimethylorthoacetat
Trimethyl orthoacetate,1,1,1-Trimethoxyethane
TriMethyl orthoacetate, 98% 100ML
TriMethyl orthoacetate, 98% 500ML
Trimethyl Ortho Acetate (TMOA)
TrimethylOrthoacetate>
TRIMETHYL ORTHOACETATE FOR SYNTHESIS
TRMETHYL ORTHOACETATE
1,1,1-TRIMETHOXYETHANE
CH3C(OCH3)3
Ethane, 1,1,1-trimethoxy-
orthoacetate
TMOA
1445-45-0
145-45-0
Acetals/Ketals/Ortho Esters
Organic Building Blocks
Building Blocks
Orthoesters
Oxygen Compounds
Organic synthesis
Acetals/Ketals/Ortho Esters
Building Blocks
Chemical Synthesis
Organic Building Blocks
Oxygen Compounds
Orthoesters
