Eliglustat
- CAS No.
- 491833-29-5
- Chemical Name:
- Eliglustat
- Synonyms
- CS-1540;Genz 99067;Eliglustat;Eliglustate;Elli Gustast;Eliglustat Free Base;Eliglustat(Genz-99067);Eliglustat(GENZ 112638);Eliglustat, 10 mM in DMSO;GENZ-99067; GENZ99067; GENZ 99067
- CBNumber:
- CB52627796
- Molecular Formula:
- C23H36N2O4
- Molecular Weight:
- 404.54
- MDL Number:
- MFCD19443735
- MOL File:
- 491833-29-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Eliglustat | TRC-E508030-5MG | 5mg | $92 |
| Eliglustat | FD158477 | 25mg | $227.25 |
| Eliglustat | FD158477 | 50mg | $363 |
| Eliglustat | FD158477 | 100mg | $582 |
| Eliglustat | FD158477 | 250mg | $1002.5 |
| More product size | |||
| Melting point | 87-92°C |
|---|---|
| Boiling point | 615.5±55.0 °C(Predicted) |
| Density | 1.123±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 13.45±0.20(Predicted) |
| color | White to Off-White |
| InChIKey | FJZZPCZKBUKGGU-AUSIDOKSSA-N |
| SMILES | N3(CCCC3)C[C@@H](NC(=O)CCCCCCC)[C@H](O)c1cc2c(cc1)OCCO2 |
| FDA UNII | DR40J4WA67 |
| NCI Drug Dictionary | eliglustat |
| ATC code | A16AX10 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS07,GHS08,GHS02 |
|---|---|
| Signal word | Danger |
| Hazard statements | H315-H319-H304-H225 |
| Precautionary statements | P501-P240-P210-P233-P243-P241-P242-P264-P280-P370+P378-P331-P337+P313-P305+P351+P338-P362+P364-P303+P361+P353-P332+P313-P301+P310-P403+P235-P405 |
| WGK Germany | WGK 3 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral STOT RE 2 |
Eliglustat price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-E508030-5MG | Eliglustat | 491833-29-5 | 5mg | $92 | 2026-06-03 | Buy |
| Biosynth | FD158477 | Eliglustat | 491833-29-5 | 25mg | $227.25 | 2026-06-04 | Buy |
| Biosynth | FD158477 | Eliglustat | 491833-29-5 | 50mg | $363 | 2026-06-04 | Buy |
| Biosynth | FD158477 | Eliglustat | 491833-29-5 | 100mg | $582 | 2026-06-04 | Buy |
| Biosynth | FD158477 | Eliglustat | 491833-29-5 | 250mg | $1002.5 | 2026-06-04 | Buy |
Eliglustat Chemical Properties,Uses,Production
Uses
Eliglustat is a specific and potent inhibitor of glucosylceramide synthase.
Definition
ChEBI: A carboxamide obtained by formal condensation of the carboxy group of octanoic acid with the primary amino group of (1R,2R)-2-amino-1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-(pyrrolidin-1-yl)propan-1-ol. A ceramide glucosyltr nsferase inhibitor used (as its tartrate salt) for treatment of Gaucher's disease.
Biological Activity
Eliglust at is a potent and selctive glucosylceramide synthase inhibitor approved for treatment of type 1 Gaucher disease.
in vivo
Mice that received drug prior to significant accumulation of substrate (10 weeks of age) showed reduced levels of glucosylceramide and number of Gaucher cells in the spleen, lung and liver when compared to age-matched control animals[1].
Eliglustat Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32997 | 60 |
| Shenzhen Excellent Biotech Co., Ltd. | 13480692018 | ramyan@ex-biotech.com | CHINA | 951 | 58 |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| Shanxi Xuanran Import and Export Trade Co., Ltd. | +8617735180244 | mike_yan@xuanranglobal.com | CHINA | 4011 | 58 |
| AFINE CHEMICALS LIMITED | +86-571-85134551 +86-18958018566 | info@afinechem.com | China | 15058 | 58 |
| BOC Sciences | 16314854226; +8616314854226 | inquiry@bocsci.com | United States | 19852 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6378 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +8619957148339 | market18@leapchem.com | China | 24569 | 58 |
| Coresyn Pharmatech Co., Ltd. | +86-571-86626709 +86-18157142896 | cbc@coresyn.com | China | 9976 | 58 |
View Lastest Price from Eliglustat manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-09 | Eliglustat
491833-29-5
|
$9.80 | 1g | ≥99% | 100kg | Career Henan Chemical Co |
-
- Eliglustat
491833-29-5
- $9.80
- ≥99%
- Career Henan Chemical Co
