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Liquiritin apioside

CAS No.
74639-14-8
Chemical Name:
Liquiritin apioside
Synonyms
Liquiritin apioside-RM;Liquiritin apioside, 10 mM in DMSO;4H-1-Benzopyran-4-one, 2-[4-[(2-O-D-apio-β-D-furanosyl-β-D-glucopyranosyl)oxy]phenyl]-2,3-dihydro-7-hydroxy-, (2S)-;(2S)-2-[4-[(2S,3R,4S,5S,6R)-3-[(2S,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-7-hydroxy-2,3-dihydrochromen-4-one
CBNumber:
CB52654123
Molecular Formula:
C26H30O13
Molecular Weight:
550.51
MDL Number:
MFCD09260034
MOL File:
74639-14-8.mol
Last updated:2025-10-09 14:55:14

Liquiritin apioside Properties

Boiling point 904.5±65.0 °C(Predicted)
Density 1.65±0.1 g/cm3 (20 ºC 760 Torr)
pka 7.70±0.40(Predicted)
form Solid
color White to light yellow
FDA UNII 8T57TH2CCD
UNSPSC Code 41116107
NACRES NA.24

Liquiritin apioside price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHL84233 Liquiritin apioside phyproof? Reference Substance 74639-14-8 10MG $495 2025-07-31 Buy
TRC L468835 LiquiritinApioside 74639-14-8 2.5mg $120 2021-12-16 Buy
Biosynth Carbosynth FL71832 Liquiritin apioside 74639-14-8 5mg $138 2021-12-16 Buy
Biosynth Carbosynth FL71832 Liquiritin apioside 74639-14-8 10mg $240 2021-12-16 Buy
Biosynth Carbosynth FL71832 Liquiritin apioside 74639-14-8 2mg $69 2021-12-16 Buy
Product number Packaging Price Buy
PHL84233 10MG $495 Buy
L468835 2.5mg $120 Buy
FL71832 5mg $138 Buy
FL71832 10mg $240 Buy
FL71832 2mg $69 Buy

Liquiritin apioside Chemical Properties,Uses,Production

Uses

Liquiritin Apioside is one of the main active components in Suan-Zao-Ren decoction as a treatment for insomnia.

Definition

ChEBI: Liquiritin apioside is a member of flavonoids and a glycoside.

in vivo

Liquiritin apioside (10 μg/μL, intralaryngeal or perineural administration; single dose; 10 min, 20 min) significantly attenuates the apnea, hypertension, and bradycardia responses to the laryngeal chemoreflex (LCR) induced by Capsaicin (HY-10448), hydrochloric acid (HCl), and distilled water (DW) in rat pups, but has no significant effect on the laryngeal mechanoreflex (LMR) induced by air pulse (AP) [1].
Liquiritin apioside (0.01 g/kg, 0.2 g/kg; po; once daily for 10 days) ameliorates DSS-induced colitis in mice, and modulates the gut microbial diversity and composition[2].

Animal Model:Laryngeal reflexe study in Sprague-Dawley rat (250-350 g) pups[1]
Dosage:10 μg/μL (diluted in saline)
Administration:Intralaryngeal perfusion for 10 minutes or peri-treatment for 20 minutes, single dose
Result:Significantly reduced the apneic responses to CAP, HCl, and DW, as well as attenuated the hypertension and bradycardia responses to these stimuli.
Did not change the cardiorespiratory responses to AP.
Peri-SLN treatment with Liquiritin apioside also suppressed the apnea, hypertension, and bradycardia responses to CAP, HCl, and DW, similar to the effect of intralaryngeal treatment.
Animal Model:DSS-induced colitis model in C57BL/6 mice (male, 18–22 g, 8–10 weeks)[2]
Dosage:0.01 g/kg, 0.02 g/kg (diluted in saline)
Administration:Oral gavaged for 10 days, once daily
Result:Exhibited the same pathological changes as that of the ABX (DSS) group mice, specifically, comparable weight loss, DAI score, colon length, and histology score.

Liquiritin apioside Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 140)Suppliers
Supplier Tel Email Country ProdList Advantage
Chengdu Greenpure Biopharma CO.,Ltd
18283602253; +8618283602253 jancyzheng@gcgreenpure.com China 954 58
Chengdu GLP biotechnology Co Ltd
028-87075086 13350802083 scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd.
+86-28-82633860; +8618080483897 sales@biopurify.com China 3751 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768 52513593@qq.com CHINA 2972 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22963 58
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19552 58
Shanghai Standard Technology Co., Ltd.
18502101150 ft-sales@nature-standard.com CHINA 1923 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29800 58
Nanjing Sky Hope Tongyuan Biological Engineering Co., Ltd.
+86-0086-025-69916489 +86-18852044786 tongyuansales@vip.sina.com China 323 58
Wuhan ChemNorm Biotech Co.,Ltd.
+86-27-8439 4403 18971486879 sales@chemnorm.com CHINA 2935 58

View Lastest Price from Liquiritin apioside manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Liquiritin apioside pictures 2025-10-09 Liquiritin apioside
74639-14-8
US $46.00-72.00 / mg 99.53% 10g TargetMol Chemicals Inc.
apioside pictures 2023-04-04 apioside
74639-14-8
US $10.00 / KG 1KG 98% 100kg Nanjing Sky Hope Tongyuan Biological Engineering Co., Ltd.
Liquiritin apioside pictures 2023-02-24 Liquiritin apioside
74639-14-8
US $0.00 / mg 5mg ≥98%(HPLC) 10 g Shanghai Standard Technology Co., Ltd.
  • apioside pictures
  • apioside
    74639-14-8
  • US $10.00 / KG
  • 98%
  • Nanjing Sky Hope Tongyuan Biological Engineering Co., Ltd.

Liquiritin apioside Spectrum

4H-1-Benzopyran-4-one, 2-[4-[(2-O-D-apio-β-D-furanosyl-β-D-glucopyranosyl)oxy]phenyl]-2,3-dihydro-7-hydroxy-, (2S)- (2S)-2-[4-[(2S,3R,4S,5S,6R)-3-[(2S,3R,4R)-3,4-dihydroxy-4-(hydroxymethyl)oxolan-2-yl]oxy-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyphenyl]-7-hydroxy-2,3-dihydrochromen-4-one Liquiritin apioside-RM Liquiritin apioside, 10 mM in DMSO 74639-14-8