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4-Chloro-2-iodo-benzoic acid Methyl ester

CAS No.
181765-85-5
Chemical Name:
4-Chloro-2-iodo-benzoic acid Methyl ester
Synonyms
methyl 2-iodo 4-chlorobenzoate;4-Chloro-2-iodo-benzoic acid Methyl ester;benzoic acid, 4-chloro-2-iodo-, methyl ester
CBNumber:
CB52671663
Molecular Formula:
C8H6ClIO2
Molecular Weight:
296.49
MDL Number:
MFCD12024993
MOL File:
181765-85-5.mol
MSDS File:
SDS
Last updated:2025-08-08 17:45:00
Product description Number Pack Size Price
Methyl 4-chloro-2-iodobenzoate 97% M48182 100mg $43
Methyl 4-chloro-2-iodobenzoate 97% M48182 250mg $48
Methyl 4-chloro-2-iodobenzoate 97% M48182 1g $50
Methyl 4-chloro-2-iodobenzoate 97% M48182 5g $120
Methyl 4-chloro-2-iodobenzoate 97% M48182 10g $1270

4-Chloro-2-iodo-benzoic acid Methyl ester Properties

storage temp. Keep in dark place,Sealed in dry,Room Temperature
Appearance Off-white to yellow Solid

4-Chloro-2-iodo-benzoic acid Methyl ester price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Synthonix M48182 Methyl 4-chloro-2-iodobenzoate 97% 181765-85-5 100mg $43 2026-05-06 Buy
Synthonix M48182 Methyl 4-chloro-2-iodobenzoate 97% 181765-85-5 250mg $48 2026-05-06 Buy
Synthonix M48182 Methyl 4-chloro-2-iodobenzoate 97% 181765-85-5 1g $50 2026-05-06 Buy
Synthonix M48182 Methyl 4-chloro-2-iodobenzoate 97% 181765-85-5 5g $120 2026-05-06 Buy
Synthonix M48182 Methyl 4-chloro-2-iodobenzoate 97% 181765-85-5 10g $1270 2026-05-06 Buy
Product number Packaging Price Buy
M48182 100mg $43 Buy
M48182 250mg $48 Buy
M48182 1g $50 Buy
M48182 5g $120 Buy
M48182 10g $1270 Buy

4-Chloro-2-iodo-benzoic acid Methyl ester Chemical Properties,Uses,Production

Synthesis

Methanol

67-56-1

4-Chloro-2-iodobenzoic acid

13421-13-1

4-Chloro-2-iodo-benzoic acid Methyl ester

181765-85-5

GENERAL PROCEDURE: To a stirred solution of 4-chloro-2-iodobenzoic acid (1.0 eq.) dissolved in anhydrous methanol (2.0 mL/1.0 mmol of 4-chloro-2-iodobenzoic acid) was added sulfinyl chloride (2.0 eq.) dropwise at 0 °C. After addition, the reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the crude product was concentrated under reduced pressure, quenched with water and extracted with ethyl acetate. The organic layers were combined, washed with saturated aqueous sodium bicarbonate, dried over anhydrous sodium sulfate, concentrated by rotary evaporation, and finally purified by column chromatography to afford the target product methyl 4-chloro-2-iodobenzoate.

References

[1] Antimicrobial Agents and Chemotherapy, 2016, vol. 60, # 7, p. 3980 - 3987
[2] Patent: US2015/105351, 2015, A1. Location in patent: Paragraph 0451
[3] ACS Medicinal Chemistry Letters, 2014, vol. 5, # 11, p. 1259 - 1262

4-Chloro-2-iodo-benzoic acid Methyl ester Preparation Products And Raw materials

4-Chloro-2-iodo-benzoic acid Methyl ester Suppliers

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4-Chloro-2-iodo-benzoic acid Methyl ester Spectrum

benzoic acid, 4-chloro-2-iodo-, methyl ester methyl 2-iodo 4-chlorobenzoate 4-Chloro-2-iodo-benzoic acid Methyl ester 181765-85-5