KHELLIN
- CAS No.
- 82-02-0
- Chemical Name:
- KHELLIN
- Synonyms
- VISNAGIN;eskel;norkel;KHELIN;keloid;ammivin;KHELLIN;chellin;kelamin;kelicor
- CBNumber:
- CB5269554
- Molecular Formula:
- C14H12O5
- Molecular Weight:
- 260.24
- MDL Number:
- MFCD00005007
- MOL File:
- 82-02-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 150154°C |
|---|---|
| Boiling point | 180200°C0.05mm Hg |
| Density | 1.1954 (rough estimate) |
| refractive index | 1.4560 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | crystalline |
| color | light yellow |
| Water Solubility | 247.2g/L(25 ºC) |
| Merck | 14,5309 |
| BRN | 263185 |
| Major Application | food and beverages |
| InChI | 1S/C14H12O5/c1-7-6-9(15)10-11(16-2)8-4-5-18-12(8)14(17-3)13(10)19-7/h4-6H,1-3H3 |
| InChIKey | HSMPDPBYAYSOBC-UHFFFAOYSA-N |
| SMILES | COc1c2OC(C)=CC(=O)c2c(OC)c3ccoc13 |
| LogP | 1.770 (est) |
| NCI Dictionary of Cancer Terms | keloid |
| FDA UNII | 5G117T0TJZ |
| EPA Substance Registry System | Khellin (82-02-0) |
| UNSPSC Code | 85151701 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301+H311+H331-H315-H319-H335 | |||||||||
| Precautionary statements | P280-P301+P310+P330-P302+P352+P312-P304+P340+P311-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 25-38-36/37/38-23/24/25 | |||||||||
| Safety Statements | 36/37/39-45-26 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | LV1050000 | |||||||||
| HS Code | 2932.99.7000 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 3 Dermal Acute Tox. 3 Inhalation Acute Tox. 3 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| Toxicity | LD50 in mice, rats (mg/kg): 30.6, 34.4 i.v.; 50.8, 68.8 orally (Busch) | |||||||||
| NFPA 704 |
|
KHELLIN price More Price(58)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHL89481 | Khellin phyproof? Reference Substance | 82-02-0 | 100MG | $339 | 2026-04-30 | Buy |
| Sigma-Aldrich | 60730 | Khellin for microscopy | 82-02-0 | 10g | $177.1 | 2026-04-30 | Buy |
| Sigma-Aldrich | 00899 | Khellin analytical standard | 82-02-0 | 100MG | $264 | 2026-04-30 | Buy |
| TCI Chemical | K0039 | Khellin >95.0%(GC) | 82-02-0 | 5g | $194 | 2026-04-30 | Buy |
| TCI Chemical | K0039 | Khellin >95.0%(GC) | 82-02-0 | 25g | $623 | 2026-04-30 | Buy |
KHELLIN Chemical Properties,Uses,Production
Uses
vasodilator (coronary), photosensitizer
Uses
Khellin has been used as a reference standard for supercritical fluid extraction of khellin from Ammi visnaga L. fruits to understand the various medicinal effects of γ-Pyrones by reversed phase HPLC method.
Definition
ChEBI: Khellin is a furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator. It has a role as a vasodilator agent, a bronchodilator agent, an anti-asthmatic agent and a cardiovascular drug. It is an organic heterotricyclic compound, an oxacycle and a furanochromone. It is functionally related to a 5H-furo[3,2-g]chromen-5-one.
brand name
Ammivin (Marion Merrell Dow); Khelloyd (Hoechst-Roussel).
Synthesis Reference(s)
Journal of Medicinal Chemistry, 26, p. 1672, 1983 DOI: 10.1021/jm00366a002
General Description
Khellin, is reported to be an efficient drug for treating vitiligo when combined with ultraviolet A irradiation.
Purification Methods
Crystallise khellin from H2O, MeOH, pet ether or Et2O. The hydrochloride has m 98o(dec) (from EtOH/HCl). [Beilstein 19 II 236, 19 III/IV 2816, 19/6 V 320.]
KHELLIN Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| BioBioPha Co., Ltd. | 0871-65217109 | y.liu@mail.biobiopha.com | China | 5641 | 65 |
| Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12323 | 58 |
| TOKYO CHEMICAL INDUSTRY CO., LTD. | 03-36680489 | Sales-JP@TCIchemicals.com | Japan | 28364 | 80 |
View Lastest Price from KHELLIN manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-27 | Khellin
82-02-0
|
$47.00-68.00 | 99.89% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-07-27 | Khellin
82-02-0
|
$47.00-68.00 | 99.89% | 10g | TargetMol Chemicals Inc. | ||
 |
2020-05-12 | Khellin
82-02-0
|
1KG | 99.0% | 500 MT | Shaanxi Dideu Medichem Co. Ltd |
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