KHELLIN
- CAS No.
- 82-02-0
- Chemical Name:
- KHELLIN
- Synonyms
- VISNAGIN;eskel;norkel;KHELIN;keloid;ammivin;KHELLIN;chellin;kelamin;kelicor
- CBNumber:
- CB5269554
- Molecular Formula:
- C14H12O5
- Molecular Weight:
- 260.24
- MDL Number:
- MFCD00005007
- MOL File:
- 82-02-0.mol
| Product description | Number | Pack Size | Price |
| Khellin phyproof? Reference Substance | PHL89481 | 100MG | $316 |
| Khellin for microscopy | 60730 | 10g | $242 |
| Khellin analytical standard | 00899 | 100MG | $175.7 |
| Khellin >95.0%(GC) | K0039 | 5g | $155 |
| Khellin >95.0%(GC) | K0039 | 25g | $497 |
| More product size | |||
| Melting point | 150154°C |
|---|---|
| Boiling point | 180200°C0.05mm Hg |
| Density | 1.1954 (rough estimate) |
| refractive index | 1.4560 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | crystalline |
| color | light yellow |
| Water Solubility | 247.2g/L(25 ºC) |
| Merck | 14,5309 |
| BRN | 263185 |
| Major Application | food and beverages |
| InChI | 1S/C14H12O5/c1-7-6-9(15)10-11(16-2)8-4-5-18-12(8)14(17-3)13(10)19-7/h4-6H,1-3H3 |
| InChIKey | HSMPDPBYAYSOBC-UHFFFAOYSA-N |
| SMILES | COc1c2OC(C)=CC(=O)c2c(OC)c3ccoc13 |
| LogP | 1.770 (est) |
| NCI Dictionary of Cancer Terms | keloid |
| FDA UNII | 5G117T0TJZ |
| EPA Substance Registry System | Khellin (82-02-0) |
| UNSPSC Code | 85151701 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301+H311+H331-H315-H319-H335 | |||||||||
| Precautionary statements | P280-P301+P310+P330-P302+P352+P312-P304+P340+P311-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 25-38-36/37/38-23/24/25 | |||||||||
| Safety Statements | 36/37/39-45-26 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | LV1050000 | |||||||||
| HS Code | 2932.99.7000 | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 3 Dermal Acute Tox. 3 Inhalation Acute Tox. 3 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| Toxicity | LD50 in mice, rats (mg/kg): 30.6, 34.4 i.v.; 50.8, 68.8 orally (Busch) | |||||||||
| NFPA 704 |
|
KHELLIN price More Price(24)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHL89481 | Khellin phyproof? Reference Substance | 82-02-0 | 100MG | $316 | 2025-07-31 | Buy |
| Sigma-Aldrich | 60730 | Khellin for microscopy | 82-02-0 | 10g | $242 | 2025-07-31 | Buy |
| Sigma-Aldrich | 00899 | Khellin analytical standard | 82-02-0 | 100MG | $175.7 | 2025-07-31 | Buy |
| TCI Chemical | K0039 | Khellin >95.0%(GC) | 82-02-0 | 5g | $155 | 2025-07-31 | Buy |
| TCI Chemical | K0039 | Khellin >95.0%(GC) | 82-02-0 | 25g | $497 | 2025-07-31 | Buy |
KHELLIN Chemical Properties,Uses,Production
Uses
vasodilator (coronary), photosensitizer
Uses
Khellin has been used as a reference standard for supercritical fluid extraction of khellin from Ammi visnaga L. fruits to understand the various medicinal effects of γ-Pyrones by reversed phase HPLC method.
Definition
ChEBI: Khellin is a furanochrome in which the basic tricyclic skeleton is substituted at positions 4 and 9 with methoxy groups and at position 7 with a methyl group. A major constituent of the plant Ammi visnaga it is a herbal folk medicine used for various illnesses, its main effect being as a vasodilator. It has a role as a vasodilator agent, a bronchodilator agent, an anti-asthmatic agent and a cardiovascular drug. It is an organic heterotricyclic compound, an oxacycle and a furanochromone. It is functionally related to a 5H-furo[3,2-g]chromen-5-one.
brand name
Ammivin (Marion Merrell Dow); Khelloyd (Hoechst-Roussel).
Synthesis Reference(s)
Journal of Medicinal Chemistry, 26, p. 1672, 1983 DOI: 10.1021/jm00366a002
General Description
Khellin, is reported to be an efficient drug for treating vitiligo when combined with ultraviolet A irradiation.
Purification Methods
Crystallise khellin from H2O, MeOH, pet ether or Et2O. The hydrochloride has m 98o(dec) (from EtOH/HCl). [Beilstein 19 II 236, 19 III/IV 2816, 19/6 V 320.]
KHELLIN Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21600 | 55 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 | sales@chemnorm.com | CHINA | 2935 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32470 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10236 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 7325 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39042 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| SUZHOU SENFEIDA CHEMICAL CO.,LTD | +86-0512-83500002 +8618662433356 | 3899766280@qq.com | China | 26362 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43339 | 58 |
View Lastest Price from KHELLIN manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-01-16 | Khellin
82-02-0
|
US $68.00-47.00 / mg | 99.93% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-01-16 | Khellin
82-02-0
|
US $68.00-47.00 / mg | 99.93% | 10g | TargetMol Chemicals Inc. | ||
 |
2020-05-12 | Khellin
82-02-0
|
US $0.00-0.00 / KG | 1KG | 99.0% | 500 MT | Shaanxi Dideu Medichem Co. Ltd |
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