VISNAGIN
- CAS No.
- 82-57-5
- Chemical Name:
- VISNAGIN
- Synonyms
- VISNAGIN;visnagine;visnagidin;VISNAGIN(P);VISNAGIN(RG);Metofuroxime;desmethoxykhellin;VISNAGIN USP/EP/BP;LABOTEST-BB LT00441024;Visnagin, 10 mM in DMSO
- CBNumber:
- CB5434295
- Molecular Formula:
- C13H10O4
- Molecular Weight:
- 230.22
- MDL Number:
- MFCD00005008
- MOL File:
- 82-57-5.mol
Melting point | 139-142 °C |
---|---|
Boiling point | 292.2°C (rough estimate) |
Density | 1.1302 (rough estimate) |
refractive index | 1.4300 (estimate) |
storage temp. | 2-8°C |
solubility | Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml). |
form | Fine Crystalline Powder |
color | Beige |
Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months. |
LogP | 2.260 (est) |
CAS DataBase Reference | 82-57-5(CAS DataBase Reference) |
FDA UNII | P64438MLBW |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P261-P305+P351+P338 |
Hazard Codes | Xn |
Risk Statements | 22 |
RTECS | LV1420000 |
HS Code | 29162000 |
VISNAGIN price More Price(13)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | T341649 | VISNAGIN Aldrich | 82-57-5 | 1g | $179 | 2024-03-01 | Buy |
TRC | V675008 | Visnagin | 82-57-5 | 500mg | $65 | 2021-12-16 | Buy |
Biosynth Carbosynth | FV42573 | Visnagin | 82-57-5 | 5G | $100 | 2021-12-16 | Buy |
Biorbyt Ltd | orb546235 | Visnagin >98% | 82-57-5 | 25mg | $127.5 | 2021-12-16 | Buy |
Biosynth Carbosynth | FV42573 | Visnagin | 82-57-5 | 10g | $175 | 2021-12-16 | Buy |
VISNAGIN Chemical Properties,Uses,Production
Description
Visnagin (82-57-5) is a natural product isolated from the plant Ammi visnaga.? It displays protective effects against doxorubicin-induced cardiomyopathy via inhibition of mitochondrial malate dehydrogenase resulting in a decrease in cardiomyocyte apoptosis.1
Chemical Properties
BEIGE FINE CRYSTALLINE POWDER
Uses
antiinflammatory, neuroprotective
Definition
ChEBI: Visnagin is a furanochromone that is furo[3,2-g]chromen-5-one which is substituted at positions 4 and 7 by methoxy and methyl groups, respectively. Found in the toothpick-plant, Ammi visnaga. It has a role as a phytotoxin, an EC 1.1.1.37 (malate dehydrogenase) inhibitor, a vasodilator agent, an antihypertensive agent, an anti-inflammatory agent and a plant metabolite. It is a furanochromone, an aromatic ether and a polyketide. It is functionally related to a 5H-furo[3,2-g]chromen-5-one.
Purification Methods
Crystallise visnagin from water. It is soluble in CHCl3 but slightly soluble in EtOH. [Aneja et al. Tetrahedron 3 230 1958, Beilstein 19 III/IV 2640.]
References
1) Liu et al. (2014), Visnagin protects against doxorubicin-induced cardiomyopathy through modulation of mitochondrial malate dehydrogenase; Sci. Transl. Med. 6 266ra170
VISNAGIN Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32268 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 22866 | 58 |
TargetMol Chemicals Inc. | support@targetmol.com | United States | 38663 | 58 | |
Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501; +undefined18621343501 | product@acmec-e.com | China | 33338 | 58 |
Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
Mainchem Co., Ltd. | +86-0592-6210733 | sale@mainchem.com | China | 32343 | 55 |
J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jk.info@jkchemical.com | China | 96815 | 76 |
Meryer (Shanghai) Chemical Technology Co., Ltd. | 021-61259108 18621169109 | market03@meryer.com | China | 40228 | 62 |
Chembest Research Laboratories Limited | +86-21-20908456 | sales@BioChemBest.com | China | 6005 | 61 |
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