VISNAGIN
- CAS No.
- 82-57-5
- Chemical Name:
- VISNAGIN
- Synonyms
- VISNAGIN;visnagine;visnagidin;VISNAGIN(P);VISNAGIN(RG);Metofuroxime;desmethoxykhellin;VISNAGIN USP/EP/BP;LABOTEST-BB LT00441024;Visnagin, 10 mM in DMSO
- CBNumber:
- CB5434295
- Molecular Formula:
- C13H10O4
- Molecular Weight:
- 230.22
- MDL Number:
- MFCD00005008
- MOL File:
- 82-57-5.mol
- MSDS File:
- SDS
| Melting point | 139-142 °C |
|---|---|
| Boiling point | 292.2°C (rough estimate) |
| Density | 1.1302 (rough estimate) |
| refractive index | 1.4300 (estimate) |
| storage temp. | 2-8°C |
| solubility | Soluble in DMSO (up to 25 mg/ml) or in Ethanol (up to 25 mg/ml). |
| form | Fine Crystalline Powder |
| color | Beige |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months. |
| LogP | 2.260 (est) |
| CAS DataBase Reference | 82-57-5(CAS DataBase Reference) |
| FDA UNII | P64438MLBW |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| RTECS | LV1420000 |
| HS Code | 29162000 |
VISNAGIN price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | T341649 | VISNAGIN AldrichCPR | 82-57-5 | 1 unit | $197 | 2026-04-30 | Buy |
| Sigma-Aldrich | T341649 | VISNAGIN Aldrich | 82-57-5 | 1g | $179 | 2024-03-01 | Buy |
| Cayman Chemical | 34140 | Visnagin ≥98% | 82-57-5 | 100mg | $35 | 2026-04-30 | Buy |
| Cayman Chemical | 34140 | Visnagin ≥98% | 82-57-5 | 500mg | $85 | 2026-04-30 | Buy |
| Cayman Chemical | 34140 | Visnagin ≥98% | 82-57-5 | 1g | $135 | 2026-04-30 | Buy |
VISNAGIN Chemical Properties, Uses, Production
Description
Visnagin (82-57-5) is a natural product isolated from the plant Ammi visnaga. It displays protective effects against doxorubicin-induced cardiomyopathy via inhibition of mitochondrial malate dehydrogenase resulting in a decrease in cardiomyocyte apoptosis.1
Chemical Properties
BEIGE FINE CRYSTALLINE POWDER
Uses
antiinflammatory, neuroprotective
Definition
ChEBI: Visnagin is a furanochromone that is furo[3,2-g]chromen-5-one which is substituted at positions 4 and 7 by methoxy and methyl groups, respectively. Found in the toothpick-plant, Ammi visnaga. It has a role as a phytotoxin, an EC 1.1.1.37 (malate dehydrogenase) inhibitor, a vasodilator agent, an antihypertensive agent, an anti-inflammatory agent and a plant metabolite. It is a furanochromone, an aromatic ether and a polyketide. It is functionally related to a 5H-furo[3,2-g]chromen-5-one.
Purification Methods
Crystallise visnagin from water. It is soluble in CHCl3 but slightly soluble in EtOH. [Aneja et al. Tetrahedron 3 230 1958, Beilstein 19 III/IV 2640.]
References
[1] YAN LIU. Visnagin protects against doxorubicin-induced cardiomyopathy through modulation of mitochondrial malate dehydrogenase[J]. Science Translational Medicine, 2014, 6 266. DOI:10.1126/scitranslmed.3010189
VISNAGIN Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
| BioBioPha Co., Ltd. | 0871-65217109 | y.liu@mail.biobiopha.com | China | 5641 | 65 |
| Thermo Fisher Scientific | 800-810-5118 | cnchemical@thermofisher.com | China | 17752 | 75 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 22497 | 55 |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3984 | 66 |
| Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8039 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7717 | 56 |
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