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OrfaMide B

CAS No.
939960-35-7
Chemical Name:
OrfaMide B
Synonyms
OrfaMide B;L-Valine, N-(3-hydroxy-1-oxotetradecyl)-L-leucyl-D-α-glutamyl-D-allothreonyl-D-valyl-L-leucyl-D-seryl-L-leucyl-L-leucyl-D-seryl-, (10→3)-lactone
CBNumber:
CB52703751
Molecular Formula:
C63H112N10O17
Molecular Weight:
1281.62
MDL Number:
MFCD33021589
MOL File:
939960-35-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:18

OrfaMide B Properties

solubility DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form A solid

OrfaMide B price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 23897 Orfamide B ≥85% 939960-35-7 1mg $272 2026-04-30 Buy
Cayman Chemical 23897 Orfamide B ≥85% 939960-35-7 5mg $951 2026-04-30 Buy
TRC O697605 OrfamideB 939960-35-7 1mg $230 2021-12-16 Buy
AK Scientific 1435EN OrfamideB 939960-35-7 1mg $368 2021-12-16 Buy
Product number Packaging Price Buy
23897 1mg $272 Buy
23897 5mg $951 Buy
O697605 1mg $230 Buy
1435EN 1mg $368 Buy

OrfaMide B Chemical Properties,Uses,Production

Description

Orfamide B is a cyclic lipopeptide originally isolated from P. fluorescens. It is the main orfamide produced by Pseudomonas sp. CMR12a. Orfamide B inhibits mycelial growth and increases hyphal branching in the fungi R. solani AG2-1 at concentrations of 10 and 100 μM and in R. solani AG 4-HGI at a concentration of 100 μM.

Uses

Orfamide B is a component of a family of cyclic lipopeptides produced by Pseudomonas fluorescens, reported in 2007. The orfamides were discovered by employing genomic analysis with an isotope-guided fractionation to identify metabolites produced by orphan gene clusters containing non-ribosomal peptide synthetases. Orfamide B has not been further investigated, although its activity is thought to parallel that of orfamide A and other cyclic lipopeptides produced by Pseudomonas.

Uses

Orfamide B is a cyclic lipopeptide produced by Pseudomonas fluorescens.

References

[1] HARALD GROSS. The genomisotopic approach: a systematic method to isolate products of orphan biosynthetic gene clusters.[J]. Chemistry & biology, 2007, 14 1: 53-63. DOI: 10.1016/j.chembiol.2006.11.007
[2] FEYISARA EYIWUMI OLORUNLEKE. Interplay between orfamides, sessilins and phenazines in the control of Rhizoctonia diseases by Pseudomonas sp. CMR12a[J]. Environmental Microbiology Reports, 2015, 7 5: 774-781. DOI: 10.1111/1758-2229.12310

OrfaMide B Preparation Products And Raw materials

Raw materials

Preparation Products

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OrfaMide B L-Valine, N-(3-hydroxy-1-oxotetradecyl)-L-leucyl-D-α-glutamyl-D-allothreonyl-D-valyl-L-leucyl-D-seryl-L-leucyl-L-leucyl-D-seryl-, (10→3)-lactone 939960-35-7 C63H112N10O17