4-Bromo-2-nitrophenol
- CAS No.
- 7693-52-9
- Chemical Name:
- 4-Bromo-2-nitrophenol
- Synonyms
- nsc402972;4-Bromo-nitrophenol;4-Bromo-2-nitrophel;4-BROMO-2-NITROPHENOL;4-bromo-2-nitro-pheno;2-NITRO-4-BROMOPHENOL;PHENOL, 2-NITRO-5-BROMO-;Phenol, 4-bromo-2-nitro-;4-Bromo-2-nitrophenol,98%;4-Bromo-2-nitrophenol >
- CBNumber:
- CB5273414
- Molecular Formula:
- C6H4BrNO3
- Molecular Weight:
- 218
- MDL Number:
- MFCD00082540
- MOL File:
- 7693-52-9.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-Bromo-2-nitrophenol 98% | 309877 | 5g | $47.1 |
| 4-Bromo-2-nitrophenol 98% | 309877 | 25g | $137 |
| 4-Bromo-2-nitrophenol >98.0%(GC) | B2363 | 5g | $46 |
| 4-Bromo-2-nitrophenol >98.0%(GC) | B2363 | 25g | $181 |
| 4-Bromo-2-nitrophenol Asreported | 262088 | 25g | $355 |
| More product size | |||
| Melting point | 90-94 °C (lit.) |
|---|---|
| Boiling point | 259.4±20.0 °C(Predicted) |
| Density | 1.8994 (rough estimate) |
| refractive index | 1.6090 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 6.28±0.14(Predicted) |
| form | Crystalline Powder or Crystals |
| color | Yellow |
| Water Solubility | Slightly soluble |
| InChI | InChI=1S/C6H4BrNO3/c7-4-1-2-6(9)5(3-4)8(10)11/h1-3,9H |
| InChIKey | CUTFAPGINUFNQM-UHFFFAOYSA-N |
| SMILES | C1(O)=CC=C(Br)C=C1[N+]([O-])=O |
| CAS DataBase Reference | 7693-52-9(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | SNK5JLK3FA |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H332-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P301+P312-P302+P352-P304+P340+P312-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22-36/37/38-20/22 | |||||||||
| Safety Statements | 26-36-36/37/39 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | SJ8370000 | |||||||||
| Hazard Note | Harmful | |||||||||
| HS Code | 29089990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Inhalation Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
4-Bromo-2-nitrophenol price More Price(81)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 309877 | 4-Bromo-2-nitrophenol 98% | 7693-52-9 | 5g | $47.1 | 2026-04-30 | Buy |
| Sigma-Aldrich | 309877 | 4-Bromo-2-nitrophenol 98% | 7693-52-9 | 25g | $137 | 2023-06-20 | Buy |
| TCI Chemical | B2363 | 4-Bromo-2-nitrophenol >98.0%(GC) | 7693-52-9 | 5g | $46 | 2026-04-30 | Buy |
| TCI Chemical | B2363 | 4-Bromo-2-nitrophenol >98.0%(GC) | 7693-52-9 | 25g | $181 | 2026-04-30 | Buy |
| Usbiological | 262088 | 4-Bromo-2-nitrophenol Asreported | 7693-52-9 | 25g | $355 | 2026-06-03 | Buy |
4-Bromo-2-nitrophenol Chemical Properties,Uses,Production
Description
4-bromo-2-nitrophenol is an essential intermediate for fine chemical engineering. It can be used to synthesize derivatives with biological activity, such as heterocyclic compounds as peptidase inhibitors for treating diabetes, introducing fluorine-containing groups as pesticides, and aminic compounds as Btk inhibitors for treating immune diseases.
Chemical Properties
yellow crystalline powder or crystals
Synthesis Reference(s)
The Journal of Organic Chemistry, 32, p. 300, 1967 DOI: 10.1021/jo01288a012
Synthesis, p. 287, 1989
General Description
The Suzuki coupling of 4-bromo-2-nitrophenol with boronic acid was studied.
Synthesis
The synthesis method of 4-bromo-2-nitrophenol comprises the following steps: preparing nitric acid with a concentration of 7-8 M; dissolving p-bromophenol in dichloroethane to obtain a substrate with a concentration of 1.8-2.2 M; injecting the nitric acid and the substrate into a continuous flow reactor through two pumps respectively, mixing, controlling the temperature at 55-75°C, the reaction pressure at 0.35-0.45 MPa, and reacting for 20-30 min.
4-Bromo-2-nitrophenol Preparation Products And Raw materials
Raw materials
1of3
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Kaitian Chemical Co., LTD | +86-13337816511 +86-13337835376 | kt_chem@126.com | China | 91 | 58 |
| Suzhou Nordica Biopharma CO.,LTD | +86-18136148818 +86-18567353071 | 3537297702@qq.com | China | 299 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20122 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Win-Win Chemical CO., Limited | 0086-577-64498589 | sales@win-winchemical.com | CHINA | 998 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | 52513593@qq.com | CHINA | 2972 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
View Lastest Price from 4-Bromo-2-nitrophenol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-06-18 | 4-Bromo-2-nitrophenol
7693-52-9
|
1KG | 98% | 2000 | Shenzhen Nexcon Pharmatechs Ltd. | ||
![]() |
2025-09-25 | 4-Bromo-2-nitrophenol
7693-52-9
|
$1.00-100.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
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2025-09-16 | 2-Nitro-4-bromophenol
7693-52-9
|
1kg | 98% | 2 tons | Nanjing Kaitian Chemical Co., LTD |
-

- 4-Bromo-2-nitrophenol
7693-52-9
- 98%
- Shenzhen Nexcon Pharmatechs Ltd.
-

- 4-Bromo-2-nitrophenol
7693-52-9
- $1.00-100.00
- 99%
- Henan Fengda Chemical Co., Ltd
-

- 2-Nitro-4-bromophenol
7693-52-9
- 98%
- Nanjing Kaitian Chemical Co., LTD







