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4-Bromo-2-nitrophenol

CAS No.
7693-52-9
Chemical Name:
4-Bromo-2-nitrophenol
Synonyms
nsc402972;4-Bromo-nitrophenol;4-Bromo-2-nitrophel;4-BROMO-2-NITROPHENOL;4-bromo-2-nitro-pheno;2-NITRO-4-BROMOPHENOL;PHENOL, 2-NITRO-5-BROMO-;Phenol, 4-bromo-2-nitro-;4-Bromo-2-nitrophenol,98%;4-Bromo-2-nitrophenol >
CBNumber:
CB5273414
Molecular Formula:
C6H4BrNO3
Molecular Weight:
218
MDL Number:
MFCD00082540
MOL File:
7693-52-9.mol
MSDS File:
SDS
Last updated:2026-05-28 05:25:05
Product description Number Pack Size Price
4-Bromo-2-nitrophenol 98% 309877 5g $47.1
4-Bromo-2-nitrophenol 98% 309877 25g $137
4-Bromo-2-nitrophenol >98.0%(GC) B2363 5g $46
4-Bromo-2-nitrophenol >98.0%(GC) B2363 25g $181
4-Bromo-2-nitrophenol Asreported 262088 25g $355
More product size

4-Bromo-2-nitrophenol Properties

Melting point 90-94 °C (lit.)
Boiling point 259.4±20.0 °C(Predicted)
Density 1.8994 (rough estimate)
refractive index 1.6090 (estimate)
storage temp. Sealed in dry,Room Temperature
pka 6.28±0.14(Predicted)
form Crystalline Powder or Crystals
color Yellow
Water Solubility Slightly soluble
InChI InChI=1S/C6H4BrNO3/c7-4-1-2-6(9)5(3-4)8(10)11/h1-3,9H
InChIKey CUTFAPGINUFNQM-UHFFFAOYSA-N
SMILES C1(O)=CC=C(Br)C=C1[N+]([O-])=O
CAS DataBase Reference 7693-52-9(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII SNK5JLK3FA
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302+H332-H315-H319-H335
Precautionary statements  P261-P264-P301+P312-P302+P352-P304+P340+P312-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes  Xn
Risk Statements  20/21/22-36/37/38-20/22
Safety Statements  26-36-36/37/39
WGK Germany  3
RTECS  SJ8370000
Hazard Note  Harmful
HS Code  29089990
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
3 0

4-Bromo-2-nitrophenol price More Price(81)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 309877 4-Bromo-2-nitrophenol 98% 7693-52-9 5g $47.1 2026-04-30 Buy
Sigma-Aldrich 309877 4-Bromo-2-nitrophenol 98% 7693-52-9 25g $137 2023-06-20 Buy
TCI Chemical B2363 4-Bromo-2-nitrophenol >98.0%(GC) 7693-52-9 5g $46 2026-04-30 Buy
TCI Chemical B2363 4-Bromo-2-nitrophenol >98.0%(GC) 7693-52-9 25g $181 2026-04-30 Buy
Usbiological 262088 4-Bromo-2-nitrophenol Asreported 7693-52-9 25g $355 2026-06-03 Buy
Product number Packaging Price Buy
309877 5g $47.1 Buy
309877 25g $137 Buy
B2363 5g $46 Buy
B2363 25g $181 Buy
262088 25g $355 Buy

4-Bromo-2-nitrophenol Chemical Properties,Uses,Production

Description

4-bromo-2-nitrophenol is an essential intermediate for fine chemical engineering. It can be used to synthesize derivatives with biological activity, such as heterocyclic compounds as peptidase inhibitors for treating diabetes, introducing fluorine-containing groups as pesticides, and aminic compounds as Btk inhibitors for treating immune diseases.

Chemical Properties

yellow crystalline powder or crystals

Synthesis Reference(s)

The Journal of Organic Chemistry, 32, p. 300, 1967 DOI: 10.1021/jo01288a012
Synthesis, p. 287, 1989

General Description

The Suzuki coupling of 4-bromo-2-nitrophenol with boronic acid was studied.

Synthesis

The synthesis method of 4-bromo-2-nitrophenol comprises the following steps: preparing nitric acid with a concentration of 7-8 M; dissolving p-bromophenol in dichloroethane to obtain a substrate with a concentration of 1.8-2.2 M; injecting the nitric acid and the substrate into a continuous flow reactor through two pumps respectively, mixing, controlling the temperature at 55-75°C, the reaction pressure at 0.35-0.45 MPa, and reacting for 20-30 min.

88-75-5
7693-52-9
Synthesis of 4-Bromo-2-nitrophenol from 2-Nitrophenol
Global( 278)Suppliers
Supplier Tel Email Country ProdList Advantage
Nanjing Kaitian Chemical Co., LTD
+86-13337816511 +86-13337835376 kt_chem@126.com China 91 58
Suzhou Nordica Biopharma CO.,LTD
+86-18136148818 +86-18567353071 3537297702@qq.com China 299 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 20122 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29640 60
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29812 58
Win-Win Chemical CO., Limited
0086-577-64498589 sales@win-winchemical.com CHINA 998 58
Jinan Carbotang Biotech Co.,Ltd.
+8615866703830 figo.gao@foxmail.com China 8497 58
Nanjing Dolon Biotechnology Co.,Ltd.
18905173768 52513593@qq.com CHINA 2972 58
Accela ChemBio Inc.
+1-858-6993322 info@accelachem.com United States 21193 58

View Lastest Price from 4-Bromo-2-nitrophenol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Bromo-2-nitrophenol pictures 2026-06-18 4-Bromo-2-nitrophenol
7693-52-9
1KG 98% 2000 Shenzhen Nexcon Pharmatechs Ltd.
	4-Bromo-2-nitrophenol pictures 2025-09-25 4-Bromo-2-nitrophenol
7693-52-9
$1.00-100.00 1KG 99% Henan Fengda Chemical Co., Ltd
2-Nitro-4-bromophenol pictures 2025-09-16 2-Nitro-4-bromophenol
7693-52-9
1kg 98% 2 tons Nanjing Kaitian Chemical Co., LTD
4-Bromo-2-nitrophenol,98% 4-Bromo-nitrophenol 4-BroMo-2-nitrophenol, 98% 25GR 2-Hydroxy-5-bromonitrobenzene Phenol, 4-bromo-2-nitro- 4-bromo-2-nitro-pheno nsc402972 4-BROMO-1-HYDROXY-2-NITROBENZENE 4-BROMO-2-NITROPHENOL PHENOL, 2-NITRO-5-BROMO- 2-NITRO-4-BROMOPHENOL 4-Bromo-2-nitrophenol > 4-Bromo-2-nitrophenol ISO 9001:2015 REACH 4-Bromo-2-nitrophel Ametryn Impurity 23(Terbuthylazine desethyl) 7693-52-9 769-52-9 C6H4BrNO3 BrC6H3NO2OH C6H3BrNO3 Building Blocks Oxygen Compounds Phenols Organic Building Blocks blocks Bromides NitroCompounds Aromatic Phenols Phenyls & Phenyl-Het Phenol&Thiophenol&Mercaptan Phenyls & Phenyl-Het Organic Building Blocks Oxygen Compounds Phenols