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GRANULIBERIN R

CAS No.
64704-41-2
Chemical Name:
GRANULIBERIN R
Synonyms
GRANULIBERIN R;FGFLPIYRRPAS-NH2;Granuliberin R, ≥97% (HPLC);PHE-GLY-PHE-LEU-PRO-ILE-TYR-ARG-ARG-PRO-ALA-SER-NH2;H-PHE-GLY-PHE-LEU-PRO-ILE-TYR-ARG-ARG-PRO-ALA-SER-NH2;L-Phenylalanylglycyl-L-phenylalanyl-L-leucyl-L-prolyl-L-isoleucyl-L-tyrosyl-L-arginyl-L-arginyl-L-prolyl-L-alanyl-L-serinamide;L-Serinamide, L-phenylalanylglycyl-L-phenylalanyl-L-leucyl-L-prolyl-L-isoleucyl-L-tyrosyl-L-arginyl-L-arginyl-L-prolyl-L-alanyl-
CBNumber:
CB5287743
Molecular Formula:
C69H103N19O14
Molecular Weight:
1422.68
MDL Number:
MFCD00080191
MOL File:
64704-41-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:22

GRANULIBERIN R Properties

storage temp. −20°C

SAFETY

Risk and Safety Statements

WGK Germany  3

GRANULIBERIN R price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
aablocks AA00E9T5 N-[1-[(1-amino-3-hydroxy-1-oxopropan-2-yl)amino]-1-oxopropan-2-yl]-1-[2-[[2-[[2-[[2-[[1-[2-[[2-[[2-[(2-amino-3-phenylpropanoyl)amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-3-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carboxamide ≥95% 64704-41-2 1mg $138 2026-05-28 Buy
aablocks AA00E9T5 N-[1-[(1-amino-3-hydroxy-1-oxopropan-2-yl)amino]-1-oxopropan-2-yl]-1-[2-[[2-[[2-[[2-[[1-[2-[[2-[[2-[(2-amino-3-phenylpropanoyl)amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-3-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carboxamide ≥95% 64704-41-2 5mg $322 2026-05-28 Buy
aablocks AA00E9T5 N-[1-[(1-amino-3-hydroxy-1-oxopropan-2-yl)amino]-1-oxopropan-2-yl]-1-[2-[[2-[[2-[[2-[[1-[2-[[2-[[2-[(2-amino-3-phenylpropanoyl)amino]acetyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]pyrrolidine-2-carbonyl]amino]-3-methylpentanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carboxamide ≥95% 64704-41-2 10mg $444 2026-05-28 Buy
Usbiological G8940 Granuliberin-R 64704-41-2 1mg $531 2021-12-16 Buy
American Custom Chemicals Corporation PEP0001651 GRANULIBERIN R 95.00% 64704-41-2 2MG $619.08 2021-12-16 Buy
Product number Packaging Price Buy
AA00E9T5 1mg $138 Buy
AA00E9T5 5mg $322 Buy
AA00E9T5 10mg $444 Buy
G8940 1mg $531 Buy
PEP0001651 2MG $619.08 Buy

GRANULIBERIN R Chemical Properties, Uses, Production

Uses

Granuliberin R is a new mast cell degranulating peptide comes from amphibian, can be isolated from the skin of frog Rana rugosa. Granuliberin R is a dodecapeptide, can act on rat peritoneal mast cell to liberate granules and release histamine[1][2].

in vivo

Granuliberin R (0.1 mg/mL, 1 μg/mL, and 10 ng/mL; injection; single dose for 60 s) interfere in the proliferation of oral keratinocytes and the activity of connective tissue cells when treatment is conducted into rats mandibular gingiva in the vicinity of the right mental foramen[4].

References

[1] Nakajima T, et al. A new mast cell degranulating peptide, granuliberin-R, in the frog (Rana rugosa) skin. Chem Pharm Bull (Tokyo). 1977 Sep;25(9):2464-5. DOI:10.1248/cpb.25.2464
[2] Yasuhara T, et al. The studies on the active peptide in the skin of Rana rugosa. II. The structure of ranatensin-R, the new ranatensin analogue, and granuliberin-R, the new mast cell degranulating peptide. Chem Pharm Bull (Tokyo). 1979 Feb;27(2):492-8. DOI:10.1248/cpb.27.492
[3] Vitale N, et al. Exocytosis in chromaffin cells: evidence for a MgATP-independent step that requires a pertussis toxin-sensitive GTP-binding protein. Biochem J. 1994 May 15;300 ( Pt 1)(Pt 1):217-27. DOI:10.1042/bj3000217
[4] Kozakiewicz M, et al. Modulation of the mitotic activity and population of the mast cells in the oral mucosa by substance P. Cell Mol Biol Lett. 2003;8(3):727-34. PMID:12949612

GRANULIBERIN R Preparation Products And Raw materials

Raw materials

Preparation Products

GRANULIBERIN R Suppliers

Global Suppliers ( 79)
Supplier Tel Email Country ProdList Advantage
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15350 60
Watson Biotechnology Co.,Ltd 027-59207879 1972026995 18140587686 sales@3600chem.com China 4192 55
Beijing Solarbio Science & Tecnology Co., Ltd. 17801761073 18101056239 3193328036@qq.com China 28150 68
Nanjing Leon Biological Technology Co., Ltd. 025-84523390 -127; 17705183659 sales@njleonbiotech.com China 5501 55
Nanjing Peptide Biotech Ltd. 025-58361106-805 15951641583 zhao.xu@njpeptide.com China 9976 55
Chengdu Youngshe Chemical Co., Ltd. +86-17380623303 Caroline@youngshechem.com China 4725 58
Hangzhou Peptidego Biotech Co.,Ltd. 0571-87213919 15967184799 Eric@peptidego.com China 7872 58
Hangzhou Go Top Peptide Biotech 0571-88211921 sales1@gotopbio.com CHINA 2609 58

View Latest Price from GRANULIBERIN R manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
GRANULIBERIN R pictures 2020-03-06 GRANULIBERIN R
64704-41-2
$1.00 1g ≥98% Career Henan Chemical Co
GRANULIBERIN R H-PHE-GLY-PHE-LEU-PRO-ILE-TYR-ARG-ARG-PRO-ALA-SER-NH2 FGFLPIYRRPAS-NH2 PHE-GLY-PHE-LEU-PRO-ILE-TYR-ARG-ARG-PRO-ALA-SER-NH2 L-Phenylalanylglycyl-L-phenylalanyl-L-leucyl-L-prolyl-L-isoleucyl-L-tyrosyl-L-arginyl-L-arginyl-L-prolyl-L-alanyl-L-serinamide Granuliberin R, ≥97% (HPLC) L-Serinamide, L-phenylalanylglycyl-L-phenylalanyl-L-leucyl-L-prolyl-L-isoleucyl-L-tyrosyl-L-arginyl-L-arginyl-L-prolyl-L-alanyl- 64704-41-2 Peptides Other Peptides Biochemicals and Reagents Amino Acids and Peptides BioChemical Peptide