Phytosphingosine
- CAS No.
- 554-62-1
- Chemical Name:
- Phytosphingosine
- Synonyms
- D-ribo-Phytosphingosine;4-HYDROXYSPHINGANINE;(2S,3S,4R)-2-aminooctadecane-1,3,4-triol;Glycolipid;Phytospingosine;4-D-Hydroxysphinganine;Salicyl phytosphingosine;PHYTOSPHINGOSINE HYDROCHLORIDE;Phyto-S;hytosphingosine
- CBNumber:
- CB5289606
- Molecular Formula:
- C18H39NO3
- Molecular Weight:
- 317.51
- MDL Number:
- MFCD02259274
- MOL File:
- 554-62-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 102 °C |
|---|---|
| Boiling point | 483.7±40.0 °C(Predicted) |
| Density | 0.983 |
| vapor pressure | 0.2Pa at 20℃ |
| refractive index | 9 ° (C=1, Pyridine) |
| storage temp. | −20°C |
| solubility | Soluble in Ethanol (up to 2 mg/ml). |
| pka | 11.91±0.45(Predicted) |
| form | White to off-white solid. |
| color | White |
| Water Solubility | 2.6mg/L at 20℃ |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in ethanol may be stored at -20°C for up to 1 month. |
| Cosmetics Ingredients Functions |
SKIN CONDITIONING HAIR CONDITIONING |
| InChI | InChI=1S/C18H39NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(21)18(22)16(19)15-20/h16-18,20-22H,2-15,19H2,1H3/t16-,17+,18-/m0/s1 |
| InChIKey | AERBNCYCJBRYDG-KSZLIROESA-N |
| SMILES | C(O)[C@H](N)[C@H](O)[C@H](O)CCCCCCCCCCCCCC |
| LogP | 6.2 at 22℃ |
| EWG's Food Scores | 1 |
| FDA UNII | GIN46U9Q2Q |
| UNSPSC Code | 12352211 |
| NACRES | NA.25 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| WGK Germany | 1 | |||||||||
| HS Code | 29221990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
Phytosphingosine price More Price(45)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | P2795 | Phytosphingosine hydrochloride ≥98%, from | 554-62-1 | 5mg | $432 | 2026-04-30 | Buy |
| TCI Chemical | P1765 | Phytosphingosine >98.0%(T) | 554-62-1 | 1g | $92 | 2026-04-30 | Buy |
| TCI Chemical | P1765 | Phytosphingosine >98.0%(T) | 554-62-1 | 5g | $276 | 2026-04-30 | Buy |
| Cayman Chemical | 20217 | Phytosphingosine (yeast) ≥95% | 554-62-1 | 5mg | $43 | 2026-04-30 | Buy |
| Cayman Chemical | 20217 | Phytosphingosine (yeast) ≥95% | 554-62-1 | 10mg | $77 | 2026-04-30 | Buy |
Phytosphingosine Chemical Properties, Uses, Production
Description
Phytosphingosine is a sphingolipid with a hydroxyl group at the C4 position that is found mainly in fungi and plants but also in animals, including humans. It is metabolized to odd-numbered fatty acids with 2-hydroxy palmitic acid as an intermediate. Phytosphingosine dose-dependently induces cell death of CHO cells and inhibits carbachol-induced activation of phospholipase D (PLD) in CHO cells transfected with C. elegans muscarinic acetylcholine receptors. It is essential in the heat stress response in S. cerevisiae. [Matreya, LLC. Catalog No. 1330]
Chemical Properties
Off-White Solid
Uses
phytosphingosine is a sphingolipid that can improve the overall condition of skin and hair. Some sources site anti-microbial and anti-inflammatory properties. Research indicates similar activity to retinoic acid, in which case it may be particularly beneficial for aging and photo-aging skin.
Uses
Phytosphingosine is a natural anti-microbial compound and it is involved in several cellular processes such as cell differentiation and anti-inflammation.
Definition
ChEBI: Phytosphingosine is a sphingoid, an amino alcohol and a triol. It has a role as a Saccharomyces cerevisiae metabolite and a mouse metabolite. It is functionally related to a N-acyl-beta-D-galactosylphytosphingosine and a sphinganine. It is a conjugate base of a phytosphingosine(1+).
Origin
In 1884, chemist J.L.W coined the word phytosphingosine, which was taken from the term “sphingoid”, a major component in all biological membranes. There are four types of sphingoid bases and phytosphingosine is one of them. Phytosphingosine is a widely distributed natural sphingoid base and found in fungi, plants, and animals.
Flammability and Explosibility
Not classified
Veterinary Drugs and Treatments
Phytosphingosine is a unique topical antiseborrheic compound. It is in a class called ceramides which are waxy materials meant to meant to mimic the normal lipid composition of the stratum corneum. It may also have some antiinflammatory and antimicrobial properties.
References
[1] CAROL L FISCHER. Antibacterial activity of sphingoid bases and fatty acids against Gram-positive and Gram-negative bacteria.[J]. Antimicrobial Agents and Chemotherapy, 2012: 1157-1161. DOI:10.1128/aac.05151-11
[2] C L FISCHER. Sphingoid bases are taken up by Escherichia coli and Staphylococcus aureus and induce ultrastructural damage.[J]. Skin Pharmacology and Physiology, 2013, 26 1: 36-44. DOI:10.1159/000343175
Phytosphingosine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Kele Fine Chemical Co., Ltd | 027-59101668 19945030958 | 2223443625@qq.com | China | 7998 | 58 |
| Wuhan Augda Biotechnology Co., Ltd | 15071299552 | 262933239@qq.com | China | 7201 | 58 |
| Hangzhou Viablife Biotech Co., Ltd. | 0571-88766806 13386527431 | sales@viablife.com | China | 38 | 58 |
| Chongqing Chuanchong Technology Co., Ltd | 023-67015921 19522053615 | 1142568342@qq.com | China | 26 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
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View Latest Price from Phytosphingosine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-17 | PHYTOSPHINGOSINE
554-62-1
|
1kg/Bag | ≥98% | 50 T/Month | Hebei Qujie Technology Co., Ltd. | ||
 |
2026-08-09 | PHYTOSPHINGOSINE
13552-11-9
|
99% HPLC | 2000kgs | Chongqing Zhihe Biopharmaceutical Co., Ltd. | |||
 |
2026-08-09 | Ceramides Phytosphingosine transparent oil mixture
554-62-1
|
98% HPLC | 20000kgs | Chongqing Zhihe Biopharmaceutical Co., Ltd. |
-
- PHYTOSPHINGOSINE
554-62-1
- $0.00
- ≥98%
- Hebei Qujie Technology Co., Ltd.
-
- PHYTOSPHINGOSINE
13552-11-9
- 99% HPLC
- Chongqing Zhihe Biopharmaceutical Co., Ltd.
-
- Ceramides Phytosphingosine transparent oil mixture
554-62-1
- 98% HPLC
- Chongqing Zhihe Biopharmaceutical Co., Ltd.
