Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>6-Bromo-2-methylbenzodoxazole

6-Bromo-2-methylbenzodoxazole

6-Bromo-2-methylbenzodoxazole Structure
6-Bromo-2-methylbenzodoxazole structure
CAS No.
151230-42-1
Chemical Name:
6-Bromo-2-methylbenzodoxazole
Synonyms
6-BROMO-2-METHYLBENZOXAZOLE;6-Bromo-2-methyl-benzooxazole;6-Bromo-2-methylbenzodoxazole;Benzoxazole, 6-bromo-2-methyl-;6-BroMo-2-Methyl-1,3-benzoxazole
CBNumber:
CB5309757
Molecular Formula:
C8H6BrNO
Molecular Weight:
212.04
MDL Number:
MFCD06659628
MOL File:
151230-42-1.mol
MSDS File:
SDS
Last updated:2026-09-12 18:53:28
Request For Quotation

6-Bromo-2-methylbenzodoxazole Properties

Melting point 44-49°C
Boiling point 264.8±13.0 °C(Predicted)
Density 1.606±0.06 g/cm3(Predicted)
Flash point >110℃
storage temp. Inert atmosphere,Store in freezer, under -20°C
form solid
pka -0.09±0.30(Predicted)
Appearance Yellow to orange Solid
InChI 1S/C8H6BrNO/c1-5-10-7-3-2-6(9)4-8(7)11-5/h2-4H,1H3
InChIKey ZCGXHOLCXPKKBO-UHFFFAOYSA-N
SMILES Cc1nc2ccc(Br)cc2o1
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Exclamation Mark (GHS07)
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H315-H318-H335
Precautionary statements  P280-P301+P312+P330-P302+P352-P305+P351+P338+P310
target organs Respiratory system
Hazard Codes  Xn
Risk Statements  22-37/38-41
Safety Statements  26-39
WGK Germany  3
Storage Class 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Dam. 1
Skin Irrit. 2
STOT SE 3

6-Bromo-2-methylbenzodoxazole price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 761729 6-Bromo-2-methylbenzoxazole 97% 151230-42-1 500mg $110 2023-06-20 Buy
Matrix Scientific 119806 6-Bromo-2-methylbenzo[d]oxazole 151230-42-1 1.00g $216 2026-05-18 Buy
Matrix Scientific 119806 6-Bromo-2-methylbenzo[d]oxazole 151230-42-1 5.00g $864 2026-05-18 Buy
aablocks AA00386N 6-Bromo-2-methylbenzo[d]oxazole ≥97% 151230-42-1 250mg $10 2026-05-28 Buy
aablocks AA00386N 6-Bromo-2-methylbenzo[d]oxazole ≥97% 151230-42-1 500mg $18 2026-05-28 Buy
Product number Packaging Price Buy
761729 500mg $110 Buy
119806 1.00g $216 Buy
119806 5.00g $864 Buy
AA00386N 250mg $10 Buy
AA00386N 500mg $18 Buy

6-Bromo-2-methylbenzodoxazole Chemical Properties, Uses, Production

Synthesis

2-AMINO-5-BROMOPHENOL

38191-34-3

Triethyl orthoacetate

78-39-7

6-BROMO-2-METHYLBENZODOXAZOLE

151230-42-1

Using 2-amino-5-bromophenol (561 mg, 3.00 mmol) and triethyl orthoacetate (656 μL, 3.6 mmol) as the raw material, 1,3-dibromo-5,5-dimethylglycolonide (17.2 mg, 0.060 mmol) was added as a catalyst. The reaction mixture was stirred at room temperature for 10 min. After completion of the reaction, the reaction mixture was extracted with ethyl acetate (50 mL × 2). The organic layers were combined, washed with saturated brine and dried over anhydrous magnesium sulfate. The solvent was removed by distillation under reduced pressure to obtain the crude product. The crude product was purified by silica gel column chromatography using ethyl acetate/hexane (1:4, v/v) as eluent to afford 6-bromo-2-methylbenzoxazole (560 mg, 88.5% yield).

References

[1] Journal of Medicinal Chemistry, 2015, vol. 58, # 18, p. 7241 - 7257
[2] Patent: JP2016/79108, 2016, A. Location in patent: Paragraph 0063
[3] Patent: WO2012/151525, 2012, A1. Location in patent: Page/Page column 128
[4] Patent: US2012/289496, 2012, A1. Location in patent: Page/Page column 113

6-Bromo-2-methylbenzodoxazole Preparation Products And Raw materials

Raw materials

Trimethyl orthoacetate 2-Amino-5-bromophenol Triethyl orthoacetate

Preparation Products

6-Bromo-2-methylbenzodoxazole Suppliers

Global Suppliers ( 96)
Supplier Tel Email Country ProdList Advantage
Tetranov Biopharm 13526569071 sales@leadmedpharm.com China 7881 64
Shanghai Topbiochem Technology Co., Ltd 021-58170097 info@topbiochem.com China 9510 58
Nanjing Norris-Pharm Technology Co., Ltd 13901585132 sales@norris-pharm.com China 8869 55
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 18201 56
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29985 65
Shanghai Hong-chuang Pharma Tech Co., Ltd. 18151128828 hc-sales@foxmail.com China 2635 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
ShangHai AmK Pharmaceutical Technology Co., Ltd. 微信 18019252918 18019252918 sale@amkchem.com China 14982 55
ShangHai Yuchuan Pharmaceutical Technology Co., Ltd. 02161555100 China 820 58
Shanghai XR Chemical Technology Co., Ltd. 021-31007982 18019432809; info@xrpharma.com China 694 55
Supplier Advantage
Tetranov Biopharm 64
Shanghai Topbiochem Technology Co., Ltd 58
Nanjing Norris-Pharm Technology Co., Ltd 55
9ding chemical ( Shanghai) Limited 56
Shanghai Aladdin Bio-Chem Technology Co.,LTD 65
Shanghai Hong-chuang Pharma Tech Co., Ltd. 55
Bide Pharmatech Ltd. 60
ShangHai AmK Pharmaceutical Technology Co., Ltd. 55
ShangHai Yuchuan Pharmaceutical Technology Co., Ltd. 58
Shanghai XR Chemical Technology Co., Ltd. 55

6-Bromo-2-methylbenzodoxazole Spectrum

6-BROMO-2-METHYLBENZODOXAZOLE(151230-42-1)1HNMR

151230-42-1 (6-Bromo-2-methylbenzodoxazole) Related Search:

2-Methylbenzoxazole 4-Bromo-A23187 4,6-Dibromo-2-(3-bromophenyl)-1,3-benzoxazol-5-amine 4,6-Dibromo-2-(3-fluorophenyl)-1,3-benzoxazol-5-amine 2-(1,1'-Biphenyl-4-yl)-4,6-dibromo-1,3-benzoxazol-5-amine
4,6-Dibromo-2-(3,4-dichlorophenyl)-1,3-benzoxazol-5-amine 4,6-Dibromo-2-(3,4-dimethylphenyl)-1,3-benzoxazol-5-amine 4,6-Dibromo-2-(2-chloro-4-methylphenyl)-1,3-benzoxazol-5-amine 4,6-Dibromo-2-(4-tert-butylphenyl)-1,3-benzoxazol-5-amine 4,6-Dibromo-2-(4-methylphenyl)-1,3-benzoxazol-5-amine
4,6-Dibromo-2-(2-chloro-phenyl)-benzooxazol-5-ylamine ASISCHEM U66090 4,6-Dibromo-2-(2-bromophenyl)-1,3-benzoxazol-5-amine 4,6-Dibromo-2-phenyl-1,3-benzoxazol-5-amine 4,6-Dibromo-2-(5-chloro-1-naphthyl)-1,3-benzoxazol-5-amine
4,6-Dibromo-2-(4-methoxyphenyl)-1,3-benzoxazol-5-amine 4,6-Dibromo-2-(3-chlorophenyl)-1,3-benzoxazol-5-amine 4,6-Dibromo-2-(4-fluorophenyl)-1,3-benzoxazol-5-amine

1of4

6-BROMO-2-METHYLBENZOXAZOLE 6-BroMo-2-Methyl-1,3-benzoxazole 6-Bromo-2-methyl-benzooxazole Benzoxazole, 6-bromo-2-methyl- 6-Bromo-2-methylbenzodoxazole 151230-42-1