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Xanthine Oxidase

CAS No.
9002-17-9
Chemical Name:
Xanthine Oxidase
Synonyms
EC 1.1.3.22;XOD;C:C&B41;e.c.1.2.3.2;xanthine-oxidas;XANTHINE OXIDASE;XOD,exbuttermilk;schardingerenzyme;Oxidase, xanthine;Xanthione oxidase
CBNumber:
CB5314629
Molecular Formula:
N/A
Molecular Weight:
0
MDL Number:
MFCD00082145
MOL File:
Mol file
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 03:48:23

Xanthine Oxidase Properties

storage temp. 2-8°C
form powder
color brown
biological source microbial
Specific Activity 0.4-1.0units/mg protein
EPA Substance Registry System Oxidase, xanthine (9002-17-9)
UNSPSC Code 12352204
NACRES NA.54

SAFETY

Risk and Safety Statements

Symbol(GHS)  Health Hazard (GHS08)
GHS08
Signal word  Danger
Hazard statements  H334
Precautionary statements  P261-P284-P304+P340+P312-P501
PPE Eyeshields, Gloves, type N95 (US)
Safety Statements  24/25
WGK Germany  3
RTECS  RQ8455000
10
TSCA  TSCA listed
HS Code  35079090
Storage Class 11 - Combustible Solids
Hazard Classifications Resp. Sens. 1

Xanthine Oxidase price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich X4875 Xanthine Oxidase from bovine milk Grade IV, ammonium sulfate suspension, ≥0.1?units/mg protein 9002-17-9 10units $85 2026-04-30 Buy
Sigma-Aldrich X4875 Xanthine Oxidase from bovine milk Grade IV, ammonium sulfate suspension, ≥0.1?units/mg protein 9002-17-9 40units $253 2026-04-30 Buy
Sigma-Aldrich X4875 Xanthine Oxidase from bovine milk Grade IV, ammonium sulfate suspension, ≥0.1?units/mg protein 9002-17-9 120units $611 2026-04-30 Buy
Sigma-Aldrich X4500 Xanthine Oxidase from bovine milk Grade III, ammonium sulfate suspension, ≥0.8?units/mg protein 9002-17-9 5units $106 2026-04-30 Buy
Sigma-Aldrich X4500 Xanthine Oxidase from bovine milk Grade III, ammonium sulfate suspension, ≥0.8?units/mg protein 9002-17-9 25units $372 2026-04-30 Buy
Product number Packaging Price Buy
X4875 10units $85 Buy
X4875 40units $253 Buy
X4875 120units $611 Buy
X4500 5units $106 Buy
X4500 25units $372 Buy

Xanthine Oxidase Chemical Properties, Uses, Production

Description

An enzyme that is closely related to aldehyde oxidase (EC 1.2.3.1). Both are metalloflavoproteins of about 300,000 daltons. They consist of two subunits of equal size and contain molybdenum, FAD, and iron (as Fe/S) in a ratio of 1:1:4 per subunit. These enzymes are widely distributed and catalyze a reaction in which the substrate is hydroxylated by an oxygen atom derived from water and electrons from the substrate are transferred to a variety of acceptors. These two enzymes have a broad overlapping substrate specificity including many purines, pyrimidines, and pteridines. However, xanthine, the best known substrate for xanthine oxidase, is not a substrate for aldehyde oxidase whereas the reverse is true for quaternary pyridinium compounds, such as N0 -methylnicotinamide. The role of oxygen as an electron acceptor with its production of hydrogen peroxide and the intermediate superoxide anion (both potential toxicants) may not be important in vivo since there is evidence that these enzymes are NAD-dependent dehydrogenases in vivo and become oxidases as a result of modification during purification. However, they are probably important in two types of detoxication. The first of these is the hydroxylation of exogenous aldehydes, purines, pyrimidines and other heterocyclic compounds, and the second involves the utilization of exogenous compounds as electron acceptors. Examples of the latter include the conversion of organic nitro compounds to hydroxyamino derivatives and the reduction of N-oxides to the free base.

Chemical Properties

Light brown powder

Uses

Biochemical research

Uses

Xanthine Oxidase from bovine milk has been used:

  • in the preparation of xanthine oxidase (XO) solution for 5-(diethoxyphosphoryl)-5-methyl-1-pyrroline-N-oxide (DEPMPO)-spin trapping assay
  • in invitro XO assay for screening Vietnamese medicinal plants for XO inhibitory activity
  • as a standard to determine XO activity
  • as a standard to test the synergistic effect of docosahexaenoic acid (DHA)

Uses

This enzyme is useful for enzymatic determination of inorganic phosphorus, 5′-nucleotidase and adenosine deaminase when coupled with Purine-nucleoside phosphorylase (PNP-301) and uricase (UAO-201, UAO-211).

Definition

An enzyme found in animal tissues that acts upon hypoxanthine, xanthine, aldehydes, reduced coenzyme I, etc., producing, respectively, xanthine, uric acid, acids, oxidized coenzyme I, etc.

General Description

Formerly E.C. 1.1.3.22

Biochem/physiol Actions

Hydroxylation of hypoxanthine to xanthine and xanthine to uric acid is catalyzed by xanthinebb oxidase (XO) enzyme.

Xanthine Oxidase Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 265)
Supplier Tel Email Country ProdList Advantage
Shanghai Baoman Biotechnology Co., Ltd. 021-62130998 baomanbio@163.com China 199 55
Nanjing Dulai Biotechnology Co., Ltd. 025-84699383-8003;025-846993838003-8003 18013301590 njduly@126.com China 3293 55
Shanghai Yihe Biological Technology Co., Ltd. 021-68882955 17721395025 2423903095@qq.com China 4999 58
YONG LEI SHENG WU 029-029-81162856 yongleishengwu@163.com China 20 58
BIOISCO(Lianyungang, Jiangsu) Biotechnology Co., Ltd 18082049515 2757382053@qq.com China 2995 58
Shanghai Yihui Biochemical Technology Co., LTD 17301829151 3506285926@qq.com China 9 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Sichuan Kulinan Technology Co., Ltd 400-1166-196 18981987031 cdhxsj@163.com China 11674 57
Sinopharm Chemical Reagent Co,Ltd. 86-21-63210123 sj_scrc@sinopharm.com China 9791 79

View Latest Price from Xanthine Oxidase manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Xanthine Oxidase pictures 2026-09-15 Xanthine Oxidase
9002-17-9
1G 98%min 30kg/month WUHAN FORTUNA CHEMICAL CO., LTD
Xanthine oxidase pictures 2019-07-06 Xanthine oxidase
9002-17-9
$1.00 1kg 95%-99% 1000kg Career Henan Chemical Co
e.c.1.2.3.2 hypoxanthineandxanthineoxidase schardingerenzyme xanthine-oxidas xanthineoxidaseandhypoxanthine xanthineoxidoreductase XOD XANTHINE OXIDASE XANTHINE OXIDASE, BOVINE MILK XANTHINE OXIDASE, BUTTERMILK XANTHINE OXIDASE (MICROBIAL) XANTHINE:OXYGEN OXIDOREDUCTASE tert-butyl 9-oxohexahydro-1H-pyrido[1,2-a]pyrazine-2(6H)-carboxylate XANTHINE OXIDASE ex butter Xanthine:oxygen oxidoreductase, XOD xanthine oxidase(cream) xanthopterin-oxidase xanthine oxidase, buttermilk (XOD) Hypoxanthine-xanthine oxidase Xanthine Oxidase microbial [lyophilized, ≥40 units/mg] XANTHINE OXIDASE FROM BUTTER-MILK CA.1 U/MG PROTEIN SUSPENSION Xanthine Oxidase from bovine milk,XOD, Xanthine:oxygen oxidoreductase Xanthine Oxidase microbial,XOD, Xanthine:oxygen oxidoreductase Xanthine Oxidase [microbial, 5 units/mg solid] XOD, Xanthine: oxygen oxidoreductase Xanthine Oxidase, Microbial, 40 units/Mg hypoxanthineoxidase xanthine oxidase grade I from*buttermilk Oxidase, xanthine XANTHINE OXIDASE GRADE IV FROM MILK XANTHIN-OXIDASE from buttermilk, ~0.07 U/mg XANTHINE OXIDASE FROM BUTTERMILK, LYOPH. ~0.4 U/MG* XANTHINE OXIDASE FROM BUTTERMILK SUSP. 1 .25 U/MG PROTEIN XANTHINE OXIDASE MICROBIAL, >7 U/MG XANTHINE OXIDASE GRADE III FROM*BUTTERMI LK XanthineOxidaseExButtermilk XOD,exbuttermilk Xanthine oxidase from buttermilk ca. 1 U/mg protein Xanthione oxidase Xanthine Oxidase from bovine milk xanthine oxidase from buttermilk xanthine oxidase from microorganism Xanthine Oxidase from Arthrobacter sp. Native Microbial Xanthine Oxidase Native Bovine Xanthine Oxidase C:C&B41 EC 1.1.3.22 USP/EP/BP Xanthine Oxidase ex. Microorganism, 15U/mg Xanthine Oxidase Suspension ex. Butter Milk, 1-4 U/mg protein Xanthine Oxidase>95%,>50u/mg Arthrobacter sp. Xanthione oxidase/XOD Xanthine Oxidase Activity Microplate Assay Kit Xanthine Oxidase Activity Fluorometric Microplate Assay Kit Xanthine Oxidase【X4376】 Xanthine Oxidase【X4500】 Xanthine Oxidase microbial【X2252】 Xanthine oxidase (endogenous) Xanthine oxidase (≥10 units/milligram)