Ralimetinib
- CAS No.
- 1029939-86-3
- Chemical Name:
- Ralimetinib
- Synonyms
- OZ439;Ralimetinib;Artefenomel (OZ439);XLCNVWUKICLURR-UHFFFAOYSA-N;Morpholine, 4-[2-(4-cis-dispiro[cyclohexane-1,3'-[1,2,4]trioxolane-5',2''-tricyclo[3.3.1.13,7]decan]-4-ylphenoxy)ethyl]-
- CBNumber:
- CB53159966
- Molecular Formula:
- C28H39NO5
- Molecular Weight:
- 469.61
- MDL Number:
- MFCD28902251
- MOL File:
- 1029939-86-3.mol
| Melting point | 152-154 °C |
|---|---|
| Boiling point | 608.7±55.0 °C(Predicted) |
| Density | 1.24±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C, protect from light, stored under nitrogen |
| solubility | DMSO: 10 mM |
| form | A solid |
| pka | 6.46±0.10(Predicted) |
| color | White to off-white |
| FDA UNII | RIK029813G |
Ralimetinib price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-0012378 | Artefenomel 99.41% | 1029939-86-3 | 5mg | $450 | 2021-12-16 | Buy |
| ChemScene | CS-0012378 | Artefenomel 99.41% | 1029939-86-3 | 10mg | $750 | 2021-12-16 | Buy |
| ChemScene | CS-0012378 | Artefenomel 99.41% | 1029939-86-3 | 50mg | $2250 | 2021-12-16 | Buy |
| ChemScene | CS-0012378 | Artefenomel 99.41% | 1029939-86-3 | 100mg | $3350 | 2021-12-16 | Buy |
Ralimetinib Chemical Properties,Uses,Production
Uses
Artefenomel (OZ439) is an orally active, synthetic anti-malarial compound containing an artemisinin pharmacophore with a mechanism of action similar to that of artemisinin. Artefenomel has antiviral activity against SARS-CoV-2[1][2].
IC 50
Plasmodium
References
[1] Jo?lle Jourdan, et al. Monoclonal Antibodies That Recognize the Alkylation Signature of Antimalarial Ozonides OZ277 (Arterolane) and OZ439 (Artefenomel). ACS Infect Dis. 2016 Jan 8;2(1):54-61. DOI:10.1021/acsinfecdis.5b00090
[2] Tania Massignan, et al. Antimalarial Artefenomel Inhibits Human SARS-CoV-2 Replication in Cells while Suppressing the Receptor ACE2.
[3] Robert L Clark, et al. Improved safety margin for embryotoxicity in rats for the new endoperoxide artefenomel (OZ439) as compared to artesunate. Birth Defects Res. 2018 Apr 17;110(7):553-578. DOI:10.1002/bdr2.1170
Ralimetinib Preparation Products And Raw materials
Raw materials
Preparation Products
Ralimetinib Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32433 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6312 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 39031 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9729 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11218 | 58 |
| Shanghai hongqu biomedical technology co. LTD | 88888888888 | hongquchem@qq.com | China | 5132 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24989 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5839 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11973 | 58 |
View Lastest Price from Ralimetinib manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-09-30 | Artefenomel
1029939-86-3
|
US $0.00 / removed | 10g | TargetMol Chemicals Inc. |
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- Artefenomel
1029939-86-3
- US $0.00 / removed
- TargetMol Chemicals Inc.
