Product Details
| Product Name:
Artefenomel |
CAS No.:
1029939-86-3 |
| Supply Ability:
10g |
Release date:
2025/09/30 |
Product Introduction
Bioactivity
| Name | Artefenomel |
| Description | Artefenomel (OZ439) is an orally active anti-malarial ozone analog with antiviral activity for the study of SARS-CoV-2 infections and malaria infections. |
| In vitro | Artefenomel (10 μg/mL, 2 hours of action) is capable of alkylating Plasmodium falciparum proteins. [1]
In Vero cells, Artefenomel (0.3-300 μM) dose-dependently reduced ACE2 expression and did not exhibit any cytotoxicity even at concentrations up to 300 μM. [2]
In a dose-dependent manner, Artefenomel (33-100 μM) inhibited SARS-CoV-2 and completely blocked virus-induced cytopathic effects (CPE) with an IC50 of 2.9 μM. [2] |
| In vivo | Artefenomel (0-10 μg/mL) affects erythrocytes, leading to anemia, which causes histological alterations (e.g., cell death) and significant sarcomeric abnormalities in embryos of pregnant Crl:CD(SD)BR rats. [3] |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 2.00 mg/mL (4.26 mM), Sonication is recommended.
|
| Keywords | OZ-439 | Artefenomel |
| Inhibitors Related | Flubendazole | Rosiglitazone | Kojic acid | Urethane | Hydroxychloroquine | L-Glutamic acid | Sorafenib | Metronidazole | Doxycycline | Curcumin | L-Cystine | L-Glutamine |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Price |
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Suppliers |
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Anhui Ruihan Technology Co., Ltd
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2023-08-21 |
United States