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Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate

CAS No.
132705-51-2
Chemical Name:
Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate
Synonyms
PYBROP;BROMOTRIPYRROLIDINOPHOSPHONIUM HEXAFLUOROPHOSPHATE;PYBRBOP;PYBROP(R);PYBROP(TM);PyBroP\(rg;PyBrOP®PyBrOP 97%;CAS:132705-51-2;PyBroP Novabiochem
CBNumber:
CB5318935
Molecular Formula:
C12H24BrF6N3P2
Molecular Weight:
466.19
MDL Number:
MFCD00077412
MOL File:
132705-51-2.mol
MSDS File:
SDS
Last updated:2026-01-13 11:22:24
Product description Number Pack Size Price
PyBroP Novabiochem? 8.51010 25g $390
PyBroP Novabiochem? 8.51010 100g $1160
Bromotripyrrolidinophosphonium hexafluorophosphate ≥95.0% (HPLC) 18565 1g $20.93
Bromotripyrrolidinophosphonium hexafluorophosphate ≥95.0% (HPLC) 18565 5g $142
Bromotripyrrolidinophosphonium Hexafluorophosphate >98.0%(HPLC)(N) B2680 5g $77
More product size

Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate Properties

Melting point 100 °C
storage temp. -20°C
solubility DMF: 0.4 g/mL, clear
form Powder
color White to off-white
Water Solubility moderately soluble
Sensitive Moisture Sensitive
BRN 7845702
Stability Moisture Sensitive
Major Application peptide synthesis
InChI InChI=1S/C12H24BrN3P.F6P/c13-17(14-7-1-2-8-14,15-9-3-4-10-15)16-11-5-6-12-16;1-7(2,3,4,5)6/h1-12H2;/q+1;-1
InChIKey CYKRMWNZYOIJCH-UHFFFAOYSA-N
SMILES [P+5]([F-])([F-])([F-])([F-])([F-])[F-].[P+](N1CCCC1)(N1CCCC1)(N1CCCC1)Br
CAS DataBase Reference 132705-51-2(CAS DataBase Reference)
UNSPSC Code 12352107
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Danger
Hazard statements  H314
Precautionary statements  P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi,C
Risk Statements  36/37/38-34
Safety Statements  26-36-45-36/37/39-27
WGK Germany  3
10-21
HS Code  2933 99 80
Storage Class 8A - Combustible corrosive hazardous materials
Hazard Classifications Eye Dam. 1
Skin Corr. 1B
NFPA 704
1
2 0

Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate price More Price(65)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.51010 PyBroP Novabiochem? 132705-51-2 25g $390 2025-07-31 Buy
Sigma-Aldrich 8.51010 PyBroP Novabiochem? 132705-51-2 100g $1160 2025-07-31 Buy
Sigma-Aldrich 18565 Bromotripyrrolidinophosphonium hexafluorophosphate ≥95.0% (HPLC) 132705-51-2 1g $20.93 2025-07-31 Buy
Sigma-Aldrich 18565 Bromotripyrrolidinophosphonium hexafluorophosphate ≥95.0% (HPLC) 132705-51-2 5g $142 2025-07-31 Buy
TCI Chemical B2680 Bromotripyrrolidinophosphonium Hexafluorophosphate >98.0%(HPLC)(N) 132705-51-2 5g $77 2025-07-31 Buy
Product number Packaging Price Buy
8.51010 25g $390 Buy
8.51010 100g $1160 Buy
18565 1g $20.93 Buy
18565 5g $142 Buy
B2680 5g $77 Buy

Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate Chemical Properties,Uses,Production

Chemical Properties

white to off-white powder

Uses

A stable reagent for the coupling of N-Methylamino acids in peptide synthesis.

Uses

It can be used as a coupling reagent:

  • For Suzuki–Miyaura cross-coupling of phenols and arylboronic acids to synthesize biaryls and heterobiaryls.
  • To functionalize pyrimidines (synthesized from 3,4-dihydropyrimidin-2(1H)-ones (DHPMs) via the Kappe dehydrogenation) by using various nucleophiles.
  • To synthesize formamidines by coupling with various primary amines and N,N-diisopropylethylamine.

It can also be used as an activating reagent:
  • For the activation of C-OH bond in tautomerizable heterocycles to form the phosphonium salt which aids the Sonogashira coupling of heterocycles with various alkynes.
  • For the one–pot activation of C-O bond in phenols and further coupling reaction with phosphine oxide or phosphite to form C-P bonds.

reaction suitability

reaction type: Coupling Reactions

Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 309)Suppliers
Supplier Tel Email Country ProdList Advantage
Suzhou Highfine Biotech Co.,Ltd.
+86-0512-68071238 +86-13771819922 june@highfine.com China 489 58
XINXIANG RUNYU MATERIAL CO., LTD.
+86-13592593621; +8613592593621 sales@runvmat.com China 446 58
Springchem New Material Technology Co.,Limited
+86-021-62885108 +8613917661608 info@spring-chem.com China 2068 57
Capot Chemical Co.,Ltd.
+86-(0)57185586718; +8613336195806 sales@capot.com China 29735 60
Shanghai Daken Advanced Materials Co.,Ltd
+86-2158073036 info@dakenam.com China 13676 58
AB PharmaTech,LLC
323-480-4688 sales@acrospharmatech.com United States 989 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3619 58
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29831 58
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715 admin@nexconn.com China 10405 58
Jinan Carbotang Biotech Co.,Ltd.
+8615866703830 figo.gao@foxmail.com China 8497 58

View Lastest Price from Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate pictures 2026-02-09 Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate
132705-51-2
US $0.00 / KG 1KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate pictures 2025-12-23 Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate
132705-51-2
US $0.00-0.00 / KG 1KG 98% 50KG XINXIANG RUNYU MATERIAL CO., LTD.
Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate pictures 2025-04-04 Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate
132705-51-2
US $0.00-0.00 / KG 1KG 98% 1ton Henan Aochuang Chemical Co.,Ltd.

Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate Spectrum

PYBROP PYBROP(R) PYBROP(TM) BROMOTRIPYRROLIDINOPHOSPHONIUM HEXAFLUOROPHOSPHATE BROMO-TRIS-PYRROLIDINO-PHOSPHONIUM HEXAFLUOROPHOSPHATE BROMO-TRIS-PYRROLIDINO-PHOSPHONIUM HEXFLUOROPHOSPHATE Pybrop(Bromo-Tris-PyrrolidinophosphoniumHexafluorophosphate) PyBroP\(rg Bromotri(pyrrolidin-1-yl)phosphoniumhexafluorophosphate Pyrrolidine phosphorus complex Bromo-tris-pyrrolidino-phosphonium hexafluorophosphat Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate ,97% Bromotri(1-pyrrolidinyl)phosphonium hexafluorophosphate, 97% Bromo-tris-pyrrolidi Bromo-tris-pyrrolidino-phosphoniumhexafluorophpsphate PYBRBOP BroMo-tris-pyrrolidino-phosphoniuM hexafluorophosphate, 97% 25GR BroMotri(pyrrolidin-1-yl)phosphoniuM hexafluorophosphate(V) Three pyrrolidino phosphoniuM broMide hexafluorophosphate (PYBROP) BroMotripyrrolidinophosphoniuM hexafluorophosphate, 98%+ Bromotripyrrolidinophosphonium hexafluorophosphate >=95.0% (HPLC) Bromotripyrrolidinylphosphonium hexafluorophosphate, 97% PyBrOP® Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate≥ 99% (HPLC) PyBroP Novabiochem Bromo-tris-pyrrolidinophosphoniumhexafluorophosphate(PyBrop) Bromotripyrrolidinophosphonium Hexafluorophosphate > Bromo-tris-pyrrolidino-phosphonium hexafluorophosphate, 97%, for synthesis Phosphorus(1+), bromotri-1-pyrrolidinyl-, (T-4)-, hexafluorophosphate(1-) (1:1) Bromotri(pyrrolidino)phosphonium hexafluorophosphate (PyBrOP) (T-4)-bromotri-1-pyrrolidinyl-Phosphorus(1+) hexafluorophosphate(1-) (1:1) PyBroP BroMo-tris-pyrrolidinophosphoniuMhexafluorophosp Pyrrolyl phosphonium bromide hexafluorophosphate CAS:132705-51-2 PyBrOP 97% (T-4)-Bromotri-pyrrolidin-1-yl-phosphorus(I) hexafluorophosphate(I) 132705-51-2 C12H24BrN3PPF6 C12H24N3P2BrF6 C12H24BrN3PF6P C12H24BrF6N3P2 Coupling Phosphonium/Uronium/Formamidinium Synthetic Reagents Peptide Coupling Reagent Peptide Coupling Reagents