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5-CHLORO-3-IODO-1H-INDAZOLE

CAS No.
351456-45-6
Chemical Name:
5-CHLORO-3-IODO-1H-INDAZOLE
Synonyms
351456-46-5;5-CHLORO-3-IODOINDAZOLE;5-chloro-3-iodo-2H-indazole;5-CHLORO-3-IODO-1H-INDAZOLE;1H-Indazole, 5-chloro-3-iodo-
CBNumber:
CB5322673
Molecular Formula:
C7H4ClIN2
Molecular Weight:
278.48
MDL Number:
MFCD06739146
MOL File:
351456-45-6.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 04:44:21
Product description Number Pack Size Price
5-CHLORO-3-IODO-1H-INDAZOLE 97% 22008 1G $80
5-CHLORO-3-IODO-1H-INDAZOLE 97% 22008 5G $285
5-Chloro-3-iodo-1H-indazole 96% AS50939 1g $48
5-Chloro-3-iodo-1H-indazole 96% AS50939 5g $145
5-Chloro-3-iodo-1H-indazole ≥95% OR60117 500mg $21
More product size

5-CHLORO-3-IODO-1H-INDAZOLE Properties

Boiling point 391.5±22.0 °C(Predicted)
Density 2.156±0.06 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
pka 10.85±0.40(Predicted)
Appearance Light yellow to yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22
HazardClass  IRRITANT
HS Code  2933998090

5-CHLORO-3-IODO-1H-INDAZOLE price More Price(53)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AstaTech 22008 5-CHLORO-3-IODO-1H-INDAZOLE 97% 351456-45-6 1G $80 2026-04-30 Buy
AstaTech 22008 5-CHLORO-3-IODO-1H-INDAZOLE 97% 351456-45-6 5G $285 2026-04-30 Buy
Activate Scientific AS50939 5-Chloro-3-iodo-1H-indazole 96% 351456-45-6 1g $48 2026-06-04 Buy
Activate Scientific AS50939 5-Chloro-3-iodo-1H-indazole 96% 351456-45-6 5g $145 2026-06-04 Buy
Apolloscientific OR60117 5-Chloro-3-iodo-1H-indazole ≥95% 351456-45-6 500mg $21 2026-06-04 Buy
Product number Packaging Price Buy
22008 1G $80 Buy
22008 5G $285 Buy
AS50939 1g $48 Buy
AS50939 5g $145 Buy
OR60117 500mg $21 Buy

5-CHLORO-3-IODO-1H-INDAZOLE Chemical Properties,Uses,Production

Synthesis

5-CHLORO (1H)INDAZOLE

698-26-0

5-CHLORO-3-IODO-1H-INDAZOLE

351456-45-6

General procedure for the synthesis of 3-iodo-5-chloroindazole from 5-chloro-1H-indazole: the direct iodination reaction was carried out by referring to the method previously reported by Bocchi [28] with slight modifications. The procedure was as follows: 5-chloro-1H-indazole (3 g, 25.4 mmol), iodine (12.7 g, 50.03 mmol) and potassium hydroxide (5.34 g, 95.25 mmol) were dissolved in DMF (7 mL) and the reaction was stirred for 3 h at room temperature. Upon completion of the reaction, the reaction was quenched with saturated sodium bisulfite solution (150 mL), at which time a precipitate was generated. The precipitate was collected by vacuum filtration and washed with water three times (30 mL each). The resulting solid was dried in a vacuum oven at 30 °C overnight to give 6.17 g of the light yellow solid product 3-iodo-5-chloroindazole. Yield: 100%; Melting point: 136-138 °C (literature value:[36] 134-136 °C); IR (KBr) ν (cm^-1): 3086 (NH); 424 (C-I). 1H-NMR δ (ppm): 13.50 (1H, s, H-1); 7.55 (1H, d, J=8.6 Hz, H-7); 7.45- 7.40 (2H, m, H-6 and H-4); 7.19 (1H, dd, J=7.5Hz, H-5).13C-NMR δ (ppm): 140.41; 127.22; 126.79; 121.23; 120.39; 110.51; 93.49. HRMS calculated value C7H4ClIN2: 277.9107 , measured value: 277.9109.

References

[1] Molecules, 2018, vol. 23, # 8,
[2] Patent: WO2017/98328, 2017, A2. Location in patent: Paragraph 00208
[3] Bioorganic and Medicinal Chemistry Letters, 2013, vol. 23, # 9, p. 2793 - 2800

698-26-0
351456-45-6
Synthesis of 5-CHLORO-3-IODO-1H-INDAZOLE from 5-CHLORO (1H)INDAZOLE

5-CHLORO-3-IODO-1H-INDAZOLE Preparation Products And Raw materials

Global( 113)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29640 60
Alchem Pharmtech,Inc.
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CONIER CHEM AND PHARMA LIMITED
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career henan chemical co
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Zhejiang J&C Biological Technology Co.,Limited
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Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418684 +8618949823763 sales@tnjchem.com China 25356 58
RR Scientific LLC
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GIHI CHEMICALS CO.,LIMITED
+86-571-86217390; +8618058761490 info@gihichemicals.com China 49923 58
Aladdin Scientific
tp@aladdinsci.com United States 52923 58
Wuhan Fortuna Chemical Co.,Ltd
+86-2759207851; +8618007136271 hk@fortunachem.com China 6006 58

View Lastest Price from 5-CHLORO-3-IODO-1H-INDAZOLE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-CHLORO-3-IODO-1H-INDAZOLE pictures 2020-01-14 5-CHLORO-3-IODO-1H-INDAZOLE
351456-45-6
$9.80 1g ≥99% 100kg Career Henan Chemical Co

5-CHLORO-3-IODO-1H-INDAZOLE Spectrum

5-CHLORO-3-IODO-1H-INDAZOLE 5-CHLORO-3-IODOINDAZOLE 1H-Indazole, 5-chloro-3-iodo- 351456-46-5 5-chloro-3-iodo-2H-indazole 351456-45-6 351456-46-5 C7H4ClIN3