2-Bromoterephthalic acid
- CAS No.
- 586-35-6
- Chemical Name:
- 2-Bromoterephthalic acid
- Synonyms
- BROMOTEREPHTHALIC ACID;DK7274;2-BromoterephthaL;2-BroMoterephthalic;LABOTEST-BB LT00454996;2-BROMOTEREPHTHALIC ACID;2-Bromotetraphenylquinone;Bromoterephthalic Acid >2-Bromoterephthalicacid,97%;2-BroMoterephthalic acid 95%
- CBNumber:
- CB5323524
- Molecular Formula:
- C8H5BrO4
- Molecular Weight:
- 245.03
- MDL Number:
- MFCD00002403
- MOL File:
- 586-35-6.mol
- MSDS File:
- SDS
| Melting point | 295-297 °C(lit.) |
|---|---|
| Boiling point | 421.6±40.0 °C(Predicted) |
| Density | 1.8281 (rough estimate) |
| refractive index | 1.4490 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| form | powder to crystal |
| pka | 2.44±0.10(Predicted) |
| color | White to Light yellow |
| Water Solubility | Soluble in water. |
| BRN | 2616163 |
| InChI | InChI=1S/C8H5BrO4/c9-6-3-4(7(10)11)1-2-5(6)8(12)13/h1-3H,(H,10,11)(H,12,13) |
| InChIKey | QPBGNSFASPVGTP-UHFFFAOYSA-N |
| SMILES | C1(C(O)=O)=CC=C(C(O)=O)C=C1Br |
| CAS DataBase Reference | 586-35-6(CAS DataBase Reference) |
| FDA UNII | 7D55SB5C2G |
| UNSPSC Code | 12352106 |
| NACRES | NA.23 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
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|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P301+P310-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | T,C,Xi | |||||||||
| Risk Statements | 25-36/37/38 | |||||||||
| Safety Statements | 26-36-45-37/39 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Corrosive | |||||||||
| HazardClass | 6.1 | |||||||||
| HS Code | 29173919 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Acute Tox. 3 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
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| NFPA 704 |
|
2-Bromoterephthalic acid price More Price(67)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 115274 | 2-Bromoterephthalic acid 95% | 586-35-6 | 5g | $121 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.41467 | 2-Bromoterephthalic acid for synthesis | 586-35-6 | 25g | $507 | 2026-04-30 | Buy |
| Sigma-Aldrich | 115274 | 2-Bromoterephthalic acid 95% | 586-35-6 | 25g | $399 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.41467 | 2-Bromoterephthalic acid for synthesis | 586-35-6 | 5G | $108 | 2024-03-01 | Buy |
| TCI Chemical | B1321 | Bromoterephthalic Acid >98.0%(GC) | 586-35-6 | 5g | $136 | 2026-04-30 | Buy |
2-Bromoterephthalic acid Chemical Properties,Uses,Production
Chemical Properties
white crystalline powder
Uses
2-Bromoterephthalic acid is used as a biochemical for proteomics research. It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, dyes and agrochemicals.
Synthesis
553-94-6
586-35-6
Example 6: This example describes in detail the synthesis of 2-bromoterephthalic acid using 2-bromo-1,4-dimethylbenzene as starting material. In a stirred autoclave equipped with an internal cooling coil and a reflux condenser, 2-bromo-1,4-dimethylbenzene (541 mmol) was mixed with 2-bromo-1,4-dimethylbenzene (541 mmol) containing cobalt(II) acetate tetrahydrate (0.625 mmol), manganese(II) acetate tetrahydrate (0.625 mmol), zirconium(IV) acetate (0.15 mmol) and sodium bromide (0.525 mmol) in a 500 g of 97% acetic acid solution were mixed. The mixture was stirred at a constant rate using a gas dispersion stirrer to optimize gas mixing, followed by heating the mixture to 150 °C for 2 h and maintaining it for 2 h, and then ramping up to 180 °C for 4 h. The mixture was heated to 150 °C for 2 h and then ramped up to 180 °C for 4 h. During the heating of the reaction, air was continuously vented at a back pressure of 400 psig (2.76 MPa). Upon completion of the reaction, the pressure was slowly released and the reactor was cooled to 50°C. The reaction products were drained and the reactor was rinsed with 50 g of acetic acid in two passes to collect the residual products. The white solid product was collected by diafiltration, washed with water and dried under vacuum, resulting in 113 g (85% yield) of a white solid of 2-bromoterephthalic acid with 99% purity, the structure of which was confirmed by 1H NMR.
References
[1] Patent: WO2008/82501, 2008, A1. Location in patent: Page/Page column 16-17
[2] Journal of Medicinal Chemistry, 2012, vol. 55, # 7, p. 3553 - 3557
[3] Journal of Coordination Chemistry, 2012, vol. 65, # 18, p. 3205 - 3215
[4] CrystEngComm, 2016, vol. 18, # 36, p. 6914 - 6925
[5] Patent: WO2015/97276, 2015, A1. Location in patent: Page/Page column 46; 47
2-Bromoterephthalic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Fuxin Crest Biotechnology Co. Ltd. | 13062833949 | fred.wen@crcorporation.cn | China | 853 | 58 |
| Jinan Huicheng Pharm Tech Co., Ltd. | 1566-575-0038 13258035297 | info@huipharm.com | China | 44 | 58 |
| Jinan Yaode Biotechnology Co., Ltd | 17805033575; 17805033575 | baiyu1.618@163.com | China | 391 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 |
View Lastest Price from 2-Bromoterephthalic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-08-08 | 2-Bromoterephthalic acid
586-35-6
|
$1.00 | 1KG | 98% | 100KG | Career Henan Chemical Co |
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- 2-Bromoterephthalic acid
586-35-6
- $1.00
- 98%
- Career Henan Chemical Co
