2,3,3-Trimethyl-5-methoxy-3H-indole
- CAS No.
- 31241-19-7
- Chemical Name:
- 2,3,3-Trimethyl-5-methoxy-3H-indole
- Synonyms
- 5-methoxy-2,3,3-trimethylindole;2,3,3-Trimethyl-5-methoxyindole;2,3,3-TRIMETHYL-5-METHOXY-3H-INDOLE;5-METHOXY-2,3,3-TRIMETHYL-3H-INDOLE;2,3,3-Trimethyl 5-Methoxy Indolenine;3H-Indole,5-Methoxy-2,3,3-triMethyl-;2,3,3-TRIMETHYL-5-METHOXY-3H-INDOLE,98+%
- CBNumber:
- CB5324440
- Molecular Formula:
- C12H15NO
- Molecular Weight:
- 189.25
- MDL Number:
- MFCD04972105
- MOL File:
- 31241-19-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340+P312-P305+P351+P338-P332+P313-P337+P313-P362-P403+P233-P405-P501 |
| HS Code | 2916399090 |
2,3,3-Trimethyl-5-methoxy-3H-indole price More Price(56)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 290666 | 2,3,3-Trimethyl 5-methoxy indolenine Asreported | 31241-19-7 | 250mg | $408 | 2026-06-03 | Buy |
| Usbiological | 290666 | 2,3,3-Trimethyl 5-methoxy indolenine Asreported | 31241-19-7 | 500mg | $573 | 2026-06-03 | Buy |
| Usbiological | 290666 | 2,3,3-Trimethyl 5-methoxy indolenine Asreported | 31241-19-7 | 1g | $797 | 2026-06-03 | Buy |
| Usbiological | 290666 | 2,3,3-Trimethyl 5-methoxy indolenine Asreported | 31241-19-7 | 2g | $1111 | 2026-06-03 | Buy |
| Usbiological | 290666 | 2,3,3-Trimethyl 5-methoxy indolenine Asreported | 31241-19-7 | 5g | $1573 | 2026-06-03 | Buy |
2,3,3-Trimethyl-5-methoxy-3H-indole Chemical Properties,Uses,Production
Uses
2,3,3-Trimethyl-5-methoxy-3H-indole is used as a key intermediate in the synthesis of the spirane copper ion sensor SP1 [1].
Synthesis
2,3,3-Trimethyl-5-methoxy-3H-indole was prepared by refluxing 4-methoxyphenylhydrazine hydrochloride with 3-methylbutan-2-one in a solution of glacial acetic acid for 5.5 hours. The specific reaction steps are as follows: 4-methoxyphenylhydrazine hydrochloride (4.815 g, 27.57 mmol) was added to a solution containing 3-methylbutan-2-one (5.90 mL, 55.2 mmol) in glacial acetic acid (88 mL). The solution was stirred at reflux for 5.5 h. The solution was allowed to cool to room temperature and neutralized with KOH pellets. The crude material was extracted with Et2O (3 × 100 mL), dried over MgSO4, filtered, and concentrated in vacuo. The crude product was purified by flash column chromatography (70:30, hexanes/ EtOAc) to afford 2,3,3-trimethyl-5-methoxy-3H-indole as a red amorphous solid (5.149 g, 99%) [1].
References
[1] Trevino, K. M., Tautges, B. K., Kapre, R. (2021). Highly Sensitive and Selective Spiropyran-Based Sensor for Copper(II) Quantification. ACS Omega, 6 16, 10776–10789. https://doi.org/10.1021/acsomega.1c00392



2,3,3-Trimethyl-5-methoxy-3H-indole Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Renruida Biomedical Technology Co., Ltd | 17316456674 | 1510693667@qq.com | China | 249 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Shanghai AmasPharm Co., Ltd. | 021-54540637 18621091017 | sales@amaspharm.com | China | 787 | 62 |
| Wuhan TCASChem Technology Co., Ltd. | 027-86697669 13986148687 | sales@tcaschem.com | China | 3989 | 55 |
| Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9874 | 58 | |
| Shanghai Worldyang Chemical Co.,Ltd. | 021-56795766 | sales@worldyachem.com | China | 9475 | 58 |
| Nanjing Chalf-Pharm Technology Co., Ltd. | 025-57018978 18251899859 | sales@chalf-pharm.com | China | 5855 | 50 |
| Nanjing Chempioneer Pharmaceutical Co., Ltd. | 18068075658 | sales@chempioneer.com | China | 1803 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
View Lastest Price from 2,3,3-Trimethyl-5-methoxy-3H-indole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2024-07-20 | 2,3,3-Trimethyl-5-methoxy-3H-indole
31241-19-7
|
$1.00 | 1Kg | 98% | 20T | Shaanxi Dideu Medichem Co. Ltd | |
![]() |
2019-07-06 | 2,3,3-Trimethyl-5-methoxy-3H-indole
31241-19-7
|
$1.00 | 1kg | 99% | 200kg | Career Henan Chemical Co |
-

- 2,3,3-Trimethyl-5-methoxy-3H-indole
31241-19-7
- $1.00
- 98%
- Shaanxi Dideu Medichem Co. Ltd
-

- 2,3,3-Trimethyl-5-methoxy-3H-indole
31241-19-7
- $1.00
- 99%
- Career Henan Chemical Co





