3-Amino-5-nitrobenzoic acid methyl ester
- CAS No.
- 23218-93-1
- Chemical Name:
- 3-Amino-5-nitrobenzoic acid methyl ester
- Synonyms
- 3-Amino-5-nitro-methylbenzoate;Methyl 3-amino-5-nitrobenzoate;3-amino-2-methyl-5-nitrobenzoate;3-Amino-5-nitro-benzoic acid meth;3-Amino-5-nitrobenzoic acid methyl ester;5-Amino-3-nitrobenzoic acid methyl ester;Benzoic acid, 3-aMino-5-nitro-, Methyl ester;3-AMINO-5-NITRO-BENZOIC ACID METHYL ESTER >98%;3-(Methoxycarbonyl)-5-nitroaniline, 3-Amino-5-(methoxycarbonyl)nitrobenzene
- CBNumber:
- CB5330834
- Molecular Formula:
- C8H8N2O4
- Molecular Weight:
- 196.16
- MDL Number:
- MFCD00461253
- MOL File:
- 23218-93-1.mol
- MSDS File:
- SDS
| Melting point | 165-166°C (dec.) |
|---|---|
| Boiling point | 0°C |
| Density | 1.386±0.06 g/cm3(Predicted) |
| Flash point | 0°C |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| form | powder |
| pka | 1.34±0.10(Predicted) |
| color | Yellow to red |
| InChI | InChI=1S/C8H8N2O4/c1-14-8(11)5-2-6(9)4-7(3-5)10(12)13/h2-4H,9H2,1H3 |
| InChIKey | HZVBRLJDOZZHFL-UHFFFAOYSA-N |
| SMILES | C(OC)(=O)C1=CC([N+]([O-])=O)=CC(N)=C1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P271-P261-P280 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| Hazard Note | Irritant |
| HS Code | 2922498590 |
3-Amino-5-nitrobenzoic acid methyl ester price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR0861 | Methyl 3-amino-5-nitrobenzoate >95% | 23218-93-1 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR0861 | Methyl 3-amino-5-nitrobenzoate >95% | 23218-93-1 | 5g | $90 | 2026-06-04 | Buy |
| Apolloscientific | OR0861 | Methyl 3-amino-5-nitrobenzoate >95% | 23218-93-1 | 25g | $351 | 2026-06-04 | Buy |
| Apolloscientific | OR0861 | Methyl 3-amino-5-nitrobenzoate >95% | 23218-93-1 | 100g | $1360 | 2026-06-04 | Buy |
| Matrix Scientific | 126781 | Methyl 3-amino-5-nitrobenzoate | 23218-93-1 | 1.00g | $126 | 2026-05-18 | Buy |
3-Amino-5-nitrobenzoic acid methyl ester Chemical Properties,Uses,Production
Synthesis
67-56-1
618-84-8
23218-93-1
General procedure for the synthesis of methyl 3-amino-5-nitrobenzoate from methanol and 3-amino-5-nitrobenzoic acid: The esterification reaction was carried out by passing dry hydrogen chloride gas into a solution of methanol (160 ml) containing 5-amino-3-nitrobenzoic acid (18.5 g, 0.10 mol). After the solution was saturated, the reaction mixture was stirred at room temperature overnight. Subsequently, the mixture was concentrated to a crystalline residue. The residue was dissolved in dichloromethane and washed with 5% sodium bicarbonate solution until the pH of the aqueous phase reached 7-8. The organic phase was separated, dried over magnesium sulfate and evaporated to remove the solvent. The product 18.6 g was obtained in 94% yield.1H NMR (CDCl3) data: δ 8.21 (t, 1H, J=1.5Hz), 4.19 (br s, 2H), 3.96 (s, 3H).
References
[1] Organic Letters, 2013, vol. 15, # 17, p. 4442 - 4445
[2] Patent: WO2007/29587, 2007, A1. Location in patent: Page/Page column 35
[3] Patent: WO2007/55580, 2007, A1. Location in patent: Page/Page column 16
[4] Patent: EP1953163, 2008, A1. Location in patent: Page/Page column 12
[5] Patent: WO2004/50619, 2004, A1. Location in patent: Page 16
3-Amino-5-nitrobenzoic acid methyl ester Preparation Products And Raw materials
Raw materials
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Preparation Products
3-Amino-5-nitrobenzoic acid methyl ester Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
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| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Wuhan TCASChem Technology Co., Ltd. | 027-86697669 13986148687 | sales@tcaschem.com | China | 3993 | 55 |
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| Wuhan Kaymke Chemical Co., Ltd., | 027-87342388 18086026008 | sales@kaymke.com | China | 3544 | 55 |
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| Quzhou AMK BioTech Co., Ltd | 0570-3081766 18357083060 | sales@qzamkbio.com | China | 1199 | 55 |
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