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PC-Biotin-PEG4-NHS carbonate

CAS No.
2055198-03-1
Chemical Name:
PC-Biotin-PEG4-NHS carbonate
Synonyms
PC-Biotin-PEG4-NHS carbonate;Biotin-PEG4-(CONH-PC)-NHS carbonate;1-(5-(3,19-Dioxo-23-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-6,9,12,15-tetraoxa-2,18-diazatricosyl)-2-nitrophenyl)ethyl (2,5-dioxopyrrolidin-1-yl) carbonate;Carbonic acid, 2,5-dioxo-1-pyrrolidinyl 1-[5-[23-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-3,19-dioxo-6,9,12,15-tetraoxa-2,18-diazatricos-1-yl]-2-nitrophenyl]ethyl ester
CBNumber:
CB53363985
Molecular Formula:
C35H50N6O14S
Molecular Weight:
810.87
MDL Number:
MFCD29079395
MOL File:
2055198-03-1.mol
MSDS File:
SDS
Last updated:2025-07-16 09:55:30

PC-Biotin-PEG4-NHS carbonate Properties

Density 1.39±0.1 g/cm3(Predicted)
storage temp. Storage temp. -20°C
solubility Soluble in DMSO, DCM, DMF
pka 13.90±0.40(Predicted)
form Solid
color White to off-white

PC-Biotin-PEG4-NHS carbonate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0115900 PC-Biotin-PEG4-NHS carbonate ≥97% 2055198-03-1 50mg $173 2026-06-04 Buy
ChemScene CS-0115900 PC-Biotin-PEG4-NHS carbonate ≥97% 2055198-03-1 100mg $240 2026-06-04 Buy
ChemScene CS-0115900 PC-Biotin-PEG4-NHS carbonate ≥97% 2055198-03-1 250mg $480 2026-06-04 Buy
BroadPharm bp-23108 PC-Biotin-PEG4-NHS carbonate 2055198-03-1 25MG $140 2026-05-24 Buy
BroadPharm bp-23108 PC-Biotin-PEG4-NHS carbonate 2055198-03-1 50MG $230 2026-05-24 Buy
Product number Packaging Price Buy
CS-0115900 50mg $173 Buy
CS-0115900 100mg $240 Buy
CS-0115900 250mg $480 Buy
bp-23108 25MG $140 Buy
bp-23108 50MG $230 Buy

PC-Biotin-PEG4-NHS carbonate Chemical Properties, Uses, Production

Description

PC-Biotin-PEG4-NHS carbonate is a unique amine reactive, photocleavable biotin reagent that is useful for introducing a biotin moiety to amine-containing biomolecules. The NHS carbonate portion of this compound reacts specifically with primary amine groups on the target molecule(s) to form a carbamate linkage. Captured biomolecules can be efficiently photoreleased using an inexpensive, near-UV, low intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm2).

Uses

PC-Biotin-PEG4-NHS carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

PC-Biotin-PEG4-NHS carbonate Preparation Products And Raw materials

Raw materials

Preparation Products

PC-Biotin-PEG4-NHS carbonate Suppliers

Global Suppliers ( 24)
Supplier Tel Email Country ProdList Advantage
Jinan elephant international trading co., LTD 13006575422@163.com China 6347 58
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4229 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Henan Weituxi Chemical Technology Co., Ltd. 0371-63284658 18135795563 3905209149@qq.com China 9707 58
Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 54996 58
Zhengzhou Akem Chemical Co., Ltd 13303867194 770406999@qq.com China 9949 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59929 58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 0431-80514535 19917294565 et@chemextension.com China 5061 58
Jilin Chinese Academy of Sciences-yanshen Technology 18143011203 ET-market@chemextension.com China 38906 58

View Latest Price from PC-Biotin-PEG4-NHS carbonate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PC-Biotin-PEG4-NHS carbonate pictures 2025-06-07 PC-Biotin-PEG4-NHS carbonate
2055198-03-1
25mg >98.00% 25mg Xian confluore Biological Technology Co., Ltd.

PC-Biotin-PEG4-NHS carbonate Spectrum

PC-Biotin-PEG4-NHS carbonate Carbonic acid, 2,5-dioxo-1-pyrrolidinyl 1-[5-[23-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-3,19-dioxo-6,9,12,15-tetraoxa-2,18-diazatricos-1-yl]-2-nitrophenyl]ethyl ester 1-(5-(3,19-Dioxo-23-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-6,9,12,15-tetraoxa-2,18-diazatricosyl)-2-nitrophenyl)ethyl (2,5-dioxopyrrolidin-1-yl) carbonate Biotin-PEG4-(CONH-PC)-NHS carbonate 2055198-03-1