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PC biotin-PEG3-NHS ester

CAS No.
2353409-93-3
Chemical Name:
PC biotin-PEG3-NHS ester
Synonyms
PC biotin-PEG3-NHS ester;1-(4-((4,18-Dioxo-22-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-8,11,14-trioxa-5,17-diazadocosyl)oxy)-5-methoxy-2-nitrophenyl)ethyl (2,5-dioxopyrrolidin-1-yl) carbonate;Carbonic acid, 2,5-dioxo-1-pyrrolidinyl 1-[4-[[22-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-4,18-dioxo-8,11,14-trioxa-5,17-diazadocos-1-yl]oxy]-5-methoxy-2-nitrophenyl]ethyl ester
CBNumber:
CB24846358
Molecular Formula:
C36H52N6O15S
Molecular Weight:
840.89
MDL Number:
MFCD31811520
MOL File:
2353409-93-3.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:56:55

PC biotin-PEG3-NHS ester Properties

Melting point 170 °C
Density 1.39±0.1 g/cm3(Predicted)
storage temp. -20°C
pka 13.90±0.40(Predicted)
form solid
color Off-white to light yellow
InChIKey WXAMRLAFOFNACR-VTJXTUSFSA-N
SMILES S1[C@H]([C@H]4NC(=O)N[C@H]4C1)CCCCC(=O)NCCOCCOCCOCCNC(=O)CCCOc2c(cc(c(c2)[N+](=O)[O-])C(OC(=O)ON3C(=O)CCC3=O)C)OC
UNSPSC Code 51171641
NACRES NA.22

SAFETY

Risk and Safety Statements

WGK Germany  WGK 3
Storage Class 11 - Combustible Solids

PC biotin-PEG3-NHS ester price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 901767 PC biotin-PEG3-NHS ester 2353409-93-3 25MG $349 2026-04-30 Buy
ChemScene CS-0115118 PC Biotin-PEG3-NHS ester ≥98% 2353409-93-3 100mg $1243 2026-06-04 Buy
BroadPharm bp-24161 PC Biotin-PEG3-NHS carbonate ester tech 2353409-93-3 10MG $205 2026-05-24 Buy
BroadPharm bp-24161 PC Biotin-PEG3-NHS carbonate ester tech 2353409-93-3 25MG $342 2026-05-24 Buy
BroadPharm bp-24161 PC Biotin-PEG3-NHS carbonate ester tech 2353409-93-3 100MG $904 2026-05-24 Buy
Product number Packaging Price Buy
901767 25MG $349 Buy
CS-0115118 100mg $1243 Buy
bp-24161 10MG $205 Buy
bp-24161 25MG $342 Buy
bp-24161 100MG $904 Buy

PC biotin-PEG3-NHS ester Chemical Properties, Uses, Production

Description

PC Biotin-PEG3-NHS carbonate ester is a unique amine reactive, photocleavable biotin reagent that allows for reagent-free release of the captured biomolecules from streptavidin beads. This reagent contains a biotin moiety linked to the amine reactive N-hydroxysuccinimidyl (NHS) mixed carbonate through a spacer arm containing a photocleavable moiety. The NHS portion of this compound reacts specifically with primary amine groups on the target molecule(s) to form a carbamate linkage. Captured biomolecules can be efficiently photoreleased, typically >90% in 5-25 minutes using an inexpensive, near-UV, low intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm2).

Uses

PC biotin-NHS ester is a unique amine-reactive, photocleavable biotin reagent that allows for reagent-free release of the captured biomolecules from streptavidin. This reagent contains a biotin moiety linked to the amine reactive N-hydroxysuccinimidyl (NHS) mixed carbonate through a spacer arm containing a photocleavable moiety. The NHS portion of this compound reacts specifically with primary amine groups on the target molecule(s) to form a carbamate linkage. Captured biomolecules can be efficiently photoreleased, typically >90% in 5-25 minutes using an inexpensive, near-UV, low intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm2).

reaction suitability

reaction type: click chemistry
reagent type: cross-linking reagent

IC 50

Cleavable Linker

PC biotin-PEG3-NHS ester Preparation Products And Raw materials

Raw materials

Preparation Products

PC biotin-PEG3-NHS ester Suppliers

Global Suppliers ( 29)
Supplier Tel Email Country ProdList Advantage
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4229 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1644 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Henan Weituxi Chemical Technology Co., Ltd. 0371-63284658 18135795563 3905209149@qq.com China 9707 58
Nanchang Tianzhen Biotechnology Co., Ltd 13758194781 13173652190 522013271@qq.com China 2436 58
Zhengzhou Akem Chemical Co., Ltd 13303867194 770406999@qq.com China 9949 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
Affinity(Wuhan)Ltd. 15841022315 sales@affinitytech.cn China 2980 58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 0431-80514535 19917294565 et@chemextension.com China 5061 58

View Latest Price from PC biotin-PEG3-NHS ester manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PC Biotin-PEG3-NHS carbonate ester pictures 2025-06-07 PC Biotin-PEG3-NHS carbonate ester
2353409-93-3
5mg >96.00% 5mg Xian confluore Biological Technology Co., Ltd.
PC biotin-PEG3-NHS ester Carbonic acid, 2,5-dioxo-1-pyrrolidinyl 1-[4-[[22-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-4,18-dioxo-8,11,14-trioxa-5,17-diazadocos-1-yl]oxy]-5-methoxy-2-nitrophenyl]ethyl ester 1-(4-((4,18-Dioxo-22-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-8,11,14-trioxa-5,17-diazadocosyl)oxy)-5-methoxy-2-nitrophenyl)ethyl (2,5-dioxopyrrolidin-1-yl) carbonate 2353409-93-3 ADC LINKER