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wu
- CAS No.
- 1627929-55-8
- Chemical Name:
- wu
- Synonyms
- CS-2690;PLX51107;PXL51107;PLX51109;PXL 51107 ;PXL-51107;PLX51107 (PLX 51107);PLX51107, 10 mM in DMSO;PLX51107;PLX 51107;PLX-51107;PLX 51107,Epigenetic Reader Domain,PLX51107,inhibit,PLX-51107,Inhibitor;4-[6-(3,5-Dimethyl-4-isoxazolyl)-1-[(1S)-1-(2-pyridinyl)ethyl]-1H-pyrrolo[3,2-b]pyridin-3-yl]benzoic
- CBNumber:
- CB53379667
- Molecular Formula:
- C26H22N4O3
- Molecular Weight:
- 438.48
- MDL Number:
- MFCD31657388
- MOL File:
- 1627929-55-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-28 05:21:49
| Melting point | >270°C (dec.) |
|---|---|
| Boiling point | 683.3±55.0 °C(Predicted) |
| Density | 1.32±0.1 g/cm3(Predicted) |
| storage temp. | -20°C Freezer |
| solubility | DMSO (Slightly, Heated) |
| pka | 3.68±0.10(Predicted) |
| form | Solid |
| color | White to Off-White |
| InChIKey | AMSUHYUVOVCWTP-INIZCTEOSA-N |
| SMILES | C(O)(=O)C1=CC=C(C2C3=NC=C(C4=C(C)ON=C4C)C=C3N([C@H](C3=NC=CC=C3)C)C=2)C=C1 |
| FDA UNII | W758F1L9ND |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| NFPA 704 |
|
wu price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 30742 | PLX51107 ≥98% | 1627929-55-8 | 500μg | $63 | 2026-04-30 | Buy |
| Cayman Chemical | 30742 | PLX51107 ≥98% | 1627929-55-8 | 1mg | $105 | 2026-04-30 | Buy |
| Cayman Chemical | 30742 | PLX51107 ≥98% | 1627929-55-8 | 5mg | $303 | 2026-04-30 | Buy |
| TRC | TRC-D468190-5MG | 4-[6-(3,5-Dimethyl-4-isoxazolyl)-1-[(1S)-1-(2-pyridinyl)ethyl]-1H-pyrrolo[3,2-b]pyridin-3-yl]benzoic | 1627929-55-8 | 5mg | $542 | 2026-06-03 | Buy |
| TRC | TRC-D468190-2.5MG | 4-[6-(3,5-Dimethyl-4-isoxazolyl)-1-[(1S)-1-(2-pyridinyl)ethyl]-1H-pyrrolo[3,2-b]pyridin-3-yl]benzoic | 1627929-55-8 | 2.5mg | $339 | 2026-06-03 | Buy |
wu Chemical Properties, Uses, Production
Uses
4-[6-(3,5-Dimethyl-4-isoxazolyl)-1-[(1S)-1-(2-pyridinyl)ethyl]-1H-pyrrolo[3,2-b]pyridin-3-yl]benzoic Acid, is a potent and selective BET inhibitor.
in vivo
PLX51107 (2 mg/kg, p.o.) inhibits splenomegaly by 75% in the Ba/F3 (murine IL3-dependent pro-B-cell line) splenomegaly mouse model, with the similar effect of 25 mg/kg OTX015. PLX51107 (20 mg/kg, qd, p.o.) exhibits potent antileukemic effects in disease models of aggressive chronic lymphocytic leukemia (CLL) and Richter transformation (RT) via oral administration once daily[1].
wu Preparation Products And Raw materials
Raw materials
Preparation Products
Global Suppliers ( 87)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Fujian boshi pharmaceutical technology co. LTD | 0595-22008920; 18120708884 | 393612455@qq.com | China | 257 | 58 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 | sales@meilune.com | China | 4765 | 58 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4859 | 55 | |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9799 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 8000 | 62 |
| Shanghai Rechem science Co., Ltd. | 021-31433387 15618786686 | sales@rechemscience.com | China | 2969 | 58 |
| Shanghai Chaolan Chemical Technology Center | QQ：65489617 13301690235 | Sales@ATKchemical.com | China | 9729 | 58 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 17801761073 18101056239 | 3193328036@qq.com | China | 28150 | 68 |
1627929-55-8 (wu) Related Search:
PLX51109
PXL51107
PLX51107
PLX51107;PLX 51107;PLX-51107
CS-2690
PXL 51107 ;PXL-51107
4-[6-(3,5-Dimethyl-4-isoxazolyl)-1-[(1S)-1-(2-pyridinyl)ethyl]-1H-pyrrolo[3,2-b]pyridin-3-yl]benzoic Acid
Benzoic acid, 4-[6-(3,5-dimethyl-4-isoxazolyl)-1-[(1S)-1-(2-pyridinyl)ethyl]-1H-pyrrolo[3,2-b]pyridin-3-yl]-
PLX 51107,Epigenetic Reader Domain,PLX51107,inhibit,PLX-51107,Inhibitor
(S)-4-(6-(3,5-Dimethylisoxazol-4-yl)-1-(1-(pyridin-2-yl)ethyl)-1H-pyrrolo[3,2-b]pyridin-3-yl)benzoic acid
PLX51107, 10 mM in DMSO
PLX51107 (PLX 51107)
4-[6-(3,5-Dimethyl-4-isoxazolyl)-1-[(1S)-1-(2-pyridinyl)ethyl]-1H-pyrrolo[3,2-b]pyridin-3-yl]benzoic
1627929-55-8
