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4-Methylsulphonylacetophenone

CAS No.
10297-73-1
Chemical Name:
4-Methylsulphonylacetophenone
Synonyms
Etoricoxib impurity C;4-(Methyl Sulfonyl);Etoricoxib USP RC A;Etocoxib impurity 1;4'-Mesylacetophenone;4-Methylsulphonylace;Acetophenone Impurity 2;P-METHYLSULFONYLACETOPHENONE;4-METHYLSULFONYLACETOPHENONE;Etoricoxib Related CoMpound A
CBNumber:
CB5339796
Molecular Formula:
C9H10O3S
Molecular Weight:
198.24
MDL Number:
MFCD00025072
MOL File:
10297-73-1.mol
MSDS File:
SDS
Last updated:2026-05-28 05:24:10

4-Methylsulphonylacetophenone Properties

Melting point 126-129 °C(lit.)
Boiling point 305.56°C (rough estimate)
Density 1.3339 (rough estimate)
refractive index 1.5250 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly, Heated)
form Crystalline Powder or Needles
color White to slightly yellow
InChI InChI=1S/C9H10O3S/c1-7(10)8-3-5-9(6-4-8)13(2,11)12/h3-6H,1-2H3
InChIKey KAVZYDHKJNABPC-UHFFFAOYSA-N
SMILES C(=O)(C1=CC=C(S(C)(=O)=O)C=C1)C
CAS DataBase Reference 10297-73-1(CAS DataBase Reference)
FDA UNII 9D65F147ZN
UNSPSC Code 12352100

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H332-H335
Precautionary statements  P261-P280-P305+P351+P338
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xi
Safety Statements  24/25
WGK Germany  3
HazardClass  IRRITANT
HS Code  29144000
Storage Class 13 - Non Combustible Solids
NFPA 704
1
0 0

4-Methylsulphonylacetophenone price More Price(62)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 549304 4′-(Methylsulfonyl)acetophenone 97% 10297-73-1 25g $97.8 2022-05-15 Buy
TCI Chemical M1678 4'-(Methylsulfonyl)acetophenone >98.0%(GC) 10297-73-1 25g $61 2026-04-30 Buy
TCI Chemical M1678 4'-(Methylsulfonyl)acetophenone >98.0%(GC) 10297-73-1 250g $376 2026-04-30 Buy
Usbiological 429621 4-(Methylsulfonyl)acetophenone 10297-73-1 1g $340 2026-06-03 Buy
Usbiological 429621 4-(Methylsulfonyl)acetophenone 10297-73-1 5g $432 2026-06-03 Buy
Product number Packaging Price Buy
549304 25g $97.8 Buy
M1678 25g $61 Buy
M1678 250g $376 Buy
429621 1g $340 Buy
429621 5g $432 Buy

4-Methylsulphonylacetophenone Chemical Properties,Uses,Production

Chemical Properties

white to slightly yellow cryst. powder or needles

Uses

4-(Methylsulfonyl)acetophenone is an impurity of Etoricoxib (E934100), which is a specific inhibitor of COX-2.

Uses

4′-(Methylsulfonyl)acetophenone may be used in the synthesis of:

  • 3-(4-Methylsulfonylphenyl)-4-phenyl-2(5H)-furanone with potent apoptosis-inducing ability.
  • Bromo-4-methylsulfonylacetophenone, an intermediate for preparing DL-threo-2-dichloroacetamido-1-(4-methylsulfonylphenyl)-1,3-propanediol.
  • 1-N-Substituted-3,5-diphenyl-2-pyrazoline derivatives, which show promising anti-inflammatory activity.

4-Methylsulphonylacetophenone Preparation Products And Raw materials

Global( 318)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai YouPeng Chemical Co. Ltd. 021-69005955 13701776567; youpengchem@163.com China 4153 56
Jiaxing Hengrui Biotechnology Co. LTD 0573-0573-82672231 13757365595 regen_chemical1@163.com China 4858 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60

View Lastest Price from 4-Methylsulphonylacetophenone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Methylsulphonylacetophenone pictures 2026-09-13 4-Methylsulphonylacetophenone
10297-73-1
0.99 RongNa Biotechnology Co.,Ltd
4-Methylsulphonylacetophenone pictures 2026-06-30 4-Methylsulphonylacetophenone
10297-73-1
1KG 98.0% 10000KGS Shaanxi Dideu New Materials Co. Ltd
4-Methylsulphonylacetophenone pictures 2025-04-04 4-Methylsulphonylacetophenone
10297-73-1
1KG 98% 1ton Henan Aochuang Chemical Co.,Ltd.
4-Methyi Sulfonyl Acetophenone, Rofecoxib, (4-Methanesulphonylphenyl)-ethanone 4'-(Methylsulphonyl)acetophenone 98% 4-(METHYLSULPHONYL)ACETOPHENONE 98+% 1-(4-(methylsufonyl)phenyl)ethanone Ethanone, 1-[4-(methylsulfonyl)phenyl]- 4'-Mesylacetophenone 4-Methylsulphonylacetophenone,95% 4-Methylsulphonylace 4'-(Methylsulfonyl)acetophenone, 97+% Etoricoxib Related CoMpound A 4'-(Methylsulfonyl)acetophenone 97% Etoricoxib USP Related Compound A P-METHYLSULFONYLACETOPHENONE 1-[4-(METHYLSULFONYL)PHENYL]-1-ETHANONE 1-[4-(METHYLSULFONYL)PHENYL]ETHAN-1-ONE 1-(4-(METHYLSULFONYL)PHENYL)ETHANONE 1-(4-METHANESULFONYL-PHENYL)-ETHANONE 4'-(METHYLSULPHONYL)ACETOPHENONE 4-(METHYLSULPHONYL)ACETOPHENONE 4-METHYLSULFONYLACETOPHENONE 4-METHANESULFONYLACETOPHENONE 4-ACETYLPHENYL METHYL SULPHONE 4-ACETOPHENONE METHYL SULFONE 1-[4-(methylsulphonyl)phenyl]ethan-1-one 4-(Methyl Sulfonyl) 4-MetylSulphonileAcetophenone 4'-(Methylsulfonyl)acetophenone> Etoricoxib USP RC A Acetophenone Impurity 2 Etocoxib impurity 1 4'-(Methylsulfonyl)acetophenone 4'-Methylsulphonylacetophenone 1,4-methylsulfonile Phenyl Ethanone 4′-(Methylsulfonyl)acetophenone, CAS 10297-73-1 4'-(Methylsulfonyl)acetophenon 4-(METHYLSULPHONYL)ACETOPHChemicalbookENONE98+% Etoricoxib impurity C 10297-73-1 CH3SO2C6H4COCH3 C9H10O3S Building Blocks C9 Carboxylic Acids Carbonyl Compounds Organic Building Blocks Sulfur Compounds Sulfones Osteoarthritis and Rheumatoid Arthritis bc0001