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3-[BENZYL-(2-METHOXYCARBONYL-ETHYL)-AMINO]-PROPIONIC ACID METHYL ESTER

CAS No.
793-19-1
Chemical Name:
3-[BENZYL-(2-METHOXYCARBONYL-ETHYL)-AMINO]-PROPIONIC ACID METHYL ESTER
Synonyms
dimethyl 3,3'-(benzylazanediyl)dipropionate;NSC 54971;DIMETHYL 3,3'-(BENZYLIMINO)DIPROPIONATE;DIMETHYL 3,3'-(BENZYLIMINO)DIPROPIONATE;diMethyl 3,3'-(benzylazanediyl)dipropanoate;N,N-BIS(B-(METHOXYCARBONYL)ETHYL)BENZYLAMINE;3,3'-Benzyliminobis(propanoic acid methyl) ester;3,3'-(Benzylimino)dipropionic acid dimethyl ester;3,3'-(Benzylimino)bispropionic acid dimethyl ester;3,3'-(Benzylimino)bis(propionic acid methyl) ester
CBNumber:
CB5344693
Molecular Formula:
C15H21NO4
Molecular Weight:
279.34
MDL Number:
MFCD00025891
MOL File:
793-19-1.mol
MSDS File:
SDS
Last updated:2026-05-28 05:29:18
Product description Number Pack Size Price
DIMETHYL 3,3'-(BENZYLIMINO)DIPROPIONATE AldrichCPR S535613 1 unit $197
DIMETHYL 3,3'-(BENZYLIMINO)DIPROPIONATE AldrichCPR S535613 250mg $179
3-[Benzyl-(2-methoxycarbonylethyl)amino]propionic Acid Methyl Ester TRC-B130175-500MG 500mg $154
3-[Benzyl-(2-methoxycarbonylethyl)amino]propionic Acid Methyl Ester TRC-B130175-250MG 250mg $103
3-[Benzyl-(2-methoxycarbonylethyl)amino]propionic Acid Methyl Ester TRC-B130175-100MG 100mg $53

3-[BENZYL-(2-METHOXYCARBONYL-ETHYL)-AMINO]-PROPIONIC ACID METHYL ESTER Properties

Boiling point 150-161 °C(Press: 0.6 Torr)
Density 1.108±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Methanol (Slightly)
pka 5.79±0.50(Predicted)
form Oil
color Colourless to Pale Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
REACH Registrations Inactive

3-[BENZYL-(2-METHOXYCARBONYL-ETHYL)-AMINO]-PROPIONIC ACID METHYL ESTER price More Price(46)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S535613 DIMETHYL 3,3'-(BENZYLIMINO)DIPROPIONATE AldrichCPR 793-19-1 1 unit $197 2026-04-30 Buy
Sigma-Aldrich S535613 DIMETHYL 3,3'-(BENZYLIMINO)DIPROPIONATE AldrichCPR 793-19-1 250mg $179 2024-03-01 Buy
TRC TRC-B130175-500MG 3-[Benzyl-(2-methoxycarbonylethyl)amino]propionic Acid Methyl Ester 793-19-1 500mg $154 2026-06-03 Buy
TRC TRC-B130175-250MG 3-[Benzyl-(2-methoxycarbonylethyl)amino]propionic Acid Methyl Ester 793-19-1 250mg $103 2026-06-03 Buy
TRC TRC-B130175-100MG 3-[Benzyl-(2-methoxycarbonylethyl)amino]propionic Acid Methyl Ester 793-19-1 100mg $53 2026-06-03 Buy
Product number Packaging Price Buy
S535613 1 unit $197 Buy
S535613 250mg $179 Buy
TRC-B130175-500MG 500mg $154 Buy
TRC-B130175-250MG 250mg $103 Buy
TRC-B130175-100MG 100mg $53 Buy

3-[BENZYL-(2-METHOXYCARBONYL-ETHYL)-AMINO]-PROPIONIC ACID METHYL ESTER Chemical Properties,Uses,Production

Synthesis

A neat mixture of methyl acrylate 129 (63 ml, 0.70 mol) and BnNH2 130 (25 g, 0.23 mol) was refluxed in the presence of Et3N (65 ml, 0.46 mol) overnight. Excess methyl acrylate was distilled off, the residue was taken in EtOAc and washed with water, brine, dried over anhydrous Na2SO4 and filtered. Solvent removed under reduced pressure. The resultant oil was chromatographed over silica gel using EtOAc-pet ether to furnish Michael adduct 131 as a yellow oil (58.67 g).
synthesis of dimethyl 3,3'-(benzylazanediyl)dipropionate

Uses

3-[Benzyl-(2-methoxycarbonylethyl)amino]propionic Acid Methyl Ester is used in preparation of substituted Phenyloxazolidinones as antimicrobial agents for treating antimicrobial.

References

[1] Patent: WO2017/15106, 2017, A1. Location in patent: Page/Page column 30
[2] Journal of Labelled Compounds and Radiopharmaceuticals, 2013, vol. 56, # 14, p. 722 - 725
[3] Planta Medica, 2017, vol. 83, # 5, p. 420 - 425
[4] Patent: US2017/274362, 2017, A1. Location in patent: Paragraph 0077-0079
[5] Patent: EP2570410, 2013, A1. Location in patent: Paragraph 0062

3-[BENZYL-(2-METHOXYCARBONYL-ETHYL)-AMINO]-PROPIONIC ACID METHYL ESTER Preparation Products And Raw materials

3-[BENZYL-(2-METHOXYCARBONYL-ETHYL)-AMINO]-PROPIONIC ACID METHYL ESTER Suppliers

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3-[BENZYL-(2-METHOXYCARBONYL-ETHYL)-AMINO]-PROPIONIC ACID METHYL ESTER methyl N-benzyl-N-(3-methoxy-3-oxopropyl)-beta-alaninate N,N-BIS(B-(METHOXYCARBONYL)ETHYL)BENZYLAMINE 3,3'-(Benzylimino)bis(propionic acid methyl) ester 3,3'-(Benzylimino)bispropionic acid dimethyl ester 3,3'-(Benzylimino)dipropionic acid dimethyl ester 3,3'-Benzyliminobis(propanoic acid methyl) ester N-(3-Methoxy-3-oxopropyl)-N-phenylmethyl-β-alanine methyl ester 3-[benzyl-(3-keto-3-methoxy-propyl)amino]propionic acid methyl ester methyl 3-[(3-methoxy-3-oxo-propyl)-(phenylmethyl)amino]propanoate methyl 3-[(3-methoxy-3-oxopropyl)-(phenylmethyl)amino]propanoate diMethyl 3,3'-(benzylazanediyl)dipropanoate NSC 54971 phenanthro(1,2-b)furan-10,11-dione, 6,7,8,9-tetrahydro-7-hydroxy-1-methyl-6-methylene- Methyl 3-[benzyl-(3-methoxy-3-oxo-propyl)amino]propanoate DIMETHYL 3,3'-(BENZYLIMINO)DIPROPIONATE 7-hydroxy-1-methyl-6-methylene-8,9-dihydro-7H-naphtho[1,2-g]benzofuran-10,11-dione β-Alanine, N-(3-methoxy-3-oxopropyl)-N-(phenylmethyl)-, methyl ester β-Alanine, N-(3-methoxy-3-oxopropyl)-N-(phenylmethyl)-, methyl estermethyl 3-[benzyl(3-methoxy-3-oxopropyl)amino]propanoate Methyl N-benzyl-N-(3-methoxy-3-oxopropyl)-β-alaninate DIMETHYL 3,3'-(BENZYLIMINO)DIPROPIONATE dimethyl 3,3'-(benzylazanediyl)dipropionate 793-19-1