Tetraethylene glycol dimethyl ether
- CAS No.
- 143-24-8
- Chemical Name:
- Tetraethylene glycol dimethyl ether
- Synonyms
- TETRAGLYME;TEGDME;DIMETHYLTETRAGLYCOL;2,5,8,11,14-PENTAOXAPENTADECANE;DIMETHOXYTETRAGLYCOL;BIS[2-(2-METHOXYETHOXY)ETHYL] ETHER;glyme5;Glyme-5;etraglyme;Me-PEG4-Me
- CBNumber:
- CB5350092
- Molecular Formula:
- C10H22O5
- Molecular Weight:
- 222.28
- MDL Number:
- MFCD00008505
- MOL File:
- 143-24-8.mol
- MSDS File:
- SDS
| Melting point | -30 °C (lit.) |
|---|---|
| Boiling point | 275-276 °C (lit.) |
| Density | 1.009 g/mL at 25 °C (lit.) |
| vapor density | 7.7 (vs air) |
| vapor pressure | <0.01 mm Hg ( 20 °C) |
| refractive index |
n |
| Flash point | 285 °F |
| storage temp. | Store below +30°C. |
| solubility | Chloroform (Sparingly), Methanol (Slightly) |
| form | Liquid |
| Specific Gravity | 1.01 |
| color | Clear |
| explosive limit | 0.8%(V) |
| Water Solubility | Soluble |
| Merck | 14,9208 |
| BRN | 1760005 |
| Major Application | environmental |
| InChI | 1S/C10H22O5/c1-11-3-5-13-7-9-15-10-8-14-6-4-12-2/h3-10H2,1-2H3 |
| InChIKey | ZUHZGEOKBKGPSW-UHFFFAOYSA-N |
| SMILES | COCCOCCOCCOCCOC |
| LogP | -0.84 at 23℃ |
| Surface tension | 33.74mN/m at 298.15K |
| Substances of Very High Concern (SVHC) Candidate List | Bis(2-(2-methoxyethoxy)ethyl)ether (143-24-8) |
| CAS DataBase Reference | 143-24-8(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 78L136FLZ9 |
| NIST Chemistry Reference | CH3O[CH2CH2O]4CH3(143-24-8) |
| EPA Substance Registry System | Tetraglyme (143-24-8) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H360FD | |||||||||
| Precautionary statements | P201-P308+P313 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 19-43-62-61 | |||||||||
| Safety Statements | 36-24-45-36/37-53-26 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | SB0400000 | |||||||||
| Autoignition Temperature | 510 °F | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 2909 19 90 | |||||||||
| Storage Class | 6.1C - Combustible acute toxic Cat.3 toxic compounds or compounds which causing chronic effects |
|||||||||
| Hazard Classifications | Repr. 1B | |||||||||
| Toxicity | LD50 orally in rats: 5.14 g/kg (Smyth) | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
Tetraethylene glycol dimethyl ether price More Price(34)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 8.20959 | Tetraethylene glycol dimethyl ether for synthesis | 143-24-8 | 250ML | $65.5 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.20959 | Tetraethylene glycol dimethyl ether for synthesis | 143-24-8 | 1L | $186 | 2026-04-30 | Buy |
| Sigma-Aldrich | 172405 | Tetraethylene glycol dimethyl ether ≥99% | 143-24-8 | 1kg | $194 | 2026-04-30 | Buy |
| Sigma-Aldrich | 02659 | Tetraethylene glycol dimethyl ether analytical standard | 143-24-8 | 5ml | $135 | 2022-05-15 | Buy |
| TCI Chemical | B0497 | Tetraethylene Glycol Dimethyl Ether >98.0%(GC) | 143-24-8 | 25mL | $19 | 2026-04-30 | Buy |
Tetraethylene glycol dimethyl ether Chemical Properties,Uses,Production
Chemical Properties
clear liquid
Uses
Tetraethylene glycol dimethyl ether is used as a solvent.
Uses
Tetraethylene glycol dimethyl ether is used in lithium-ion battery technology. It is associated with trifluoroethanol and used as a working pair for organic absorption heat pumps. It acts as a solvent for cleaning and degreasing due to its chemical and thermal stability. Moreover, it is suitable solvent for high temperature reactions due its high boiling point. Further, it is used in the selective adsorption of proteins during the promotion of cell adhesion.
Definition
ChEBI: Tetraglyme is a polyether.
General Description
Tetraethylene glycol dimethyl ether or tetraglyme is an organic aprotic colourless solvent with film forming ability.
Flammability and Explosibility
Non flammable
reaction suitability
reagent type: cross-linking reagent
reaction type: click chemistry
Safety Profile
Mildly toxic by ingestion. Experimental reproductive effects. An eye irritant. Many glycol ethers are suspected of having dangerous human reproductive effects. When heated to decomposition it emits acrid smoke and irritating fumes. See also GLYCOL ETHERS
Purification Methods
Stand the ether over CaH2, LiAlH4 or sodium, and distil it when required. [Beilstein 1 IV 2404.]
Advantages
Tetraethylene glycol dimethyl ether (TEGDME) could be used as a bifunctional solvent which serves as both the casting solvent and active component by controlling the residual amount of TEGDME from excessive to appropriate. This method could avoid the negative impact of the residual organic solvent (such as acetonitrile) in polymer electrolytes prepared by the solution-casting method on battery performance. The residual TEGDME serves as a plasticizer in HSE that is beneficial for improving the plasticity and decreasing the crystallinity of PEO so that it can increase the mobility of lithium ions and flexibility of solid electrolytes. TEGDME can also improve the plasticity and interfacial contact[1].
Environmental considerations
Tetraethylene glycol dimethyl ether is a polar, non-aromatic compound. It is nonionic but water-soluble due to its polarity. However, it has been detected in municipal effluents, runoff from fields irrigated with treated wastewater, and wastewaters of two different waste oil refineries Citation[2].
References
[1] Hao-Ran Wang, Ya-Nan Yang and Tao Zhang*. “Tape-Casting Method of Hybrid Solid Electrolytes with a Residual Active Solvent of Tetraethylene Glycol Dimethyl Ether.” ACS Applied Energy Materials 6 3 (2023): 2031–2038.
[2] Holger Gulyas. “Combining activated carbon adsorption with heterogeneous photocatalytic oxidation: lack of synergy for biologically treated greywater and tetraethylene glycol dimethyl ether.” Environmental Technology 34 9–12 (2013): 1393–403.
Tetraethylene glycol dimethyl ether Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Anhui Lixing Chemical Co., Ltd. | 563-+86-0563-8163717 13805622997 | hxh@lixingchem.com | China | 15 | 60 |
| Tianjinshi Haydn Science &Technology Development Co.,Ltd | 022-88294560 13642153692 | 313878807@qq.com | China | 28 | 58 |
| Jinan Yuanshang New Materials Co., Ltd. | 15269161103 | 15269161103@163.com | China | 985 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Ark Pharm, Inc. | 847-367-3680 | sales@arkpharminc.com | United States | 1669 | 56 |
| Beijing dtftchem Technology Co., Ltd. | 010-60275820 13031183356 | elainezt@sina.com | China | 1386 | 62 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
Related articles
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- Jul 1,2026
View Lastest Price from Tetraethylene glycol dimethyl ether manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-11 | Tetraethylene glycol dimethyl ether
143-24-8
|
1kg /Drum | ≥98% | 50 T/Month | Hebei Qujie Technology Co., Ltd. | ||
 |
2026-09-11 | Tetraethylene glycol dimethyl ether
143-24-8
|
1kg | 99%min | 20mt | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-06-30 | Tetraethylene glycol dimethyl ether
143-24-8
|
1KG | 98 | 10000KGS | Shaanxi Dideu New Materials Co. Ltd |
-
- Tetraethylene glycol dimethyl ether
143-24-8
- $0.00
- ≥98%
- Hebei Qujie Technology Co., Ltd.
-
- Tetraethylene glycol dimethyl ether
143-24-8
- 99%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Tetraethylene glycol dimethyl ether
143-24-8
- 98
- Shaanxi Dideu New Materials Co. Ltd
