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Tetraglyme

CAS No.
143-24-8
Chemical Name:
Tetraglyme
Synonyms
TETRAGLYME;TEGDME;DIMETHYLTETRAGLYCOL;2,5,8,11,14-PENTAOXAPENTADECANE;DIMETHOXYTETRAGLYCOL;BIS[2-(2-METHOXYETHOXY)ETHYL] ETHER;glyme5;Glyme-5;etraglyme;Me-PEG4-Me
CBNumber:
CB00129041
Molecular Formula:
C10H22O5
Molecular Weight:
222.28
MDL Number:
MFCD00008505
MOL File:
143-24-8.mol
MSDS File:
SDS
Last updated:2026-07-30 17:03:33

Tetraglyme Properties

Melting point -30 °C (lit.)
Boiling point 275-276 °C (lit.)
Density 1.009 g/mL at 25 °C (lit.)
vapor density 7.7 (vs air)
vapor pressure <0.01 mm Hg ( 20 °C)
refractive index n20/D 1.432(lit.)
Flash point 285 °F
storage temp. Store below +30°C.
solubility Chloroform (Sparingly), Methanol (Slightly)
form Liquid
Specific Gravity 1.01
color Clear
explosive limit 0.8%(V)
Water Solubility Soluble
Merck 14,9208
BRN 1760005
Major Application environmental
InChI 1S/C10H22O5/c1-11-3-5-13-7-9-15-10-8-14-6-4-12-2/h3-10H2,1-2H3
InChIKey ZUHZGEOKBKGPSW-UHFFFAOYSA-N
SMILES COCCOCCOCCOCCOC
LogP -0.84 at 23℃
Surface tension 33.74mN/m at 298.15K
Substances of Very High Concern (SVHC) Candidate List Bis(2-(2-methoxyethoxy)ethyl)ether (143-24-8)
CAS DataBase Reference 143-24-8(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 78L136FLZ9
NIST Chemistry Reference CH3O[CH2CH2O]4CH3(143-24-8)
EPA Substance Registry System Tetraglyme (143-24-8)
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  Health Hazard (GHS08)
GHS08
Signal word  Danger
Hazard statements  H360FD
Precautionary statements  P201-P308+P313
PPE Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi
Risk Statements  19-43-62-61
Safety Statements  36-24-45-36/37-53-26
WGK Germany  1
RTECS  SB0400000
Autoignition Temperature 510 °F
TSCA  TSCA listed
HS Code  2909 19 90
Storage Class 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Repr. 1B
Toxicity LD50 orally in rats: 5.14 g/kg (Smyth)
REACH Registrations Active
NFPA 704
1
0

Tetraglyme price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 8.20959 Tetraethylene glycol dimethyl ether for synthesis 143-24-8 250ML $65.5 2026-04-30 Buy
Sigma-Aldrich 8.20959 Tetraethylene glycol dimethyl ether for synthesis 143-24-8 1L $186 2026-04-30 Buy
Sigma-Aldrich 172405 Tetraethylene glycol dimethyl ether ≥99% 143-24-8 1kg $194 2026-04-30 Buy
Sigma-Aldrich 02659 Tetraethylene glycol dimethyl ether analytical standard 143-24-8 5ml $135 2022-05-15 Buy
TCI Chemical B0497 Tetraethylene Glycol Dimethyl Ether >98.0%(GC) 143-24-8 25mL $19 2026-04-30 Buy
Product number Packaging Price Buy
8.20959 250ML $65.5 Buy
8.20959 1L $186 Buy
172405 1kg $194 Buy
02659 5ml $135 Buy
B0497 25mL $19 Buy

Tetraglyme Chemical Properties, Uses, Production

Description

Tetraglyme is a widely used family of saturated polyethers for increasing anion reactivity in a given system, thus affecting selectivity and reaction rates. It is one of the heavier ethylene oxide based glymes available commercially.

Characteristics

Tetraglyme is a polar aprotic solvent with excellent chemical and thermal stability.

Uses

Tetraglyme's high boiling point and stability makes it an ideal candidate for separation processes and high temperature reactions. TEGDME is also used in lithium-ion battery technology and combined with trifluoroethanol as a working pair for organic absorption heat pumps.

Safety

Tetraglyme is listed as a Substance of Very High Concern under REACH regulations.

75-21-8
115-10-6
110-71-4
112-49-2
111-96-6
143-24-8
1191-87-3
Synthesis of Tetraglyme from Ethylene oxide and Dimethyl ether

Tetraglyme Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 478)
Supplier Tel Email Country ProdList Advantage
Anhui Lixing Chemical Co., Ltd. 563-+86-0563-8163717 13805622997 hxh@lixingchem.com China 16 60
Tianjinshi Haydn Science &Technology Development Co.,Ltd 022-88294560 13642153692 313878807@qq.com China 28 58
Jinan Yuanshang New Materials Co., Ltd. 15269161103 15269161103@163.com China 985 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Ark Pharm, Inc. 847-367-3680 sales@arkpharminc.com United States 1669 56
Beijing dtftchem Technology Co., Ltd. 010-60275820 13031183356 elainezt@sina.com China 1386 62
Beijing HwrkChemical Technology Co., Ltd 89508211 18501085097 sales.bj@hwrkchemical.com China 9407 55

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TETRA(ETHYLENE GLYCOL) DIMETHYL ETHER, 9 9+% TETRAETHYLENE GLYCOL DIMETHYL ETHER,STAN DARD FOR GC Tetraethylene glycol dimethyl ether, 98+% 2,5,8,11,14-Pentaoxapentadecane, Bis[2-(2-methoxyethoxy)ethyl] ether, Dimethoxytetraethylene glycol, Dimethyltetraglycol, Tetraglyme Tetraethylene glycol dimethyl ether, 99%, extra pure Tetraethylene glycol dimethyl ether, extra pure 1-(2-methoxyethoxy)-2-[2-(2-methoxyethoxy)-ethoxy]-ethane 1,11-dimethoxy-3,6,9-trioxa-undecane Ansol E-181 Ansul Ether 181AT ansulether181at e181(ether) Ether, bis[2-(2-methoxyethoxy)ethyl] ether,bis(2-(2-methoxyethoxy)ethyl) glyme5 Glyme-5 dimethyltetragol Bis[2-(2-methoxyethoxy)ethyl] Ether Tetraglyme Tetraethylene glycol dimethyl ether,2,5,8,11,14-Pentaoxapentadecane, Bis[2-(2-methoxyethoxy)ethyl] ether, Dimethoxytetraethylene glycol, Dimethyltetraglycol, Tetraglyme Bis(2-Methoxy-ethoxyethyl)ether Tetraethylene glycol diMethyl ether, extra pure, 99% 1KG Tetraethylene glycol diMethyl ether, extra pure, 99% 250GR CAS_143-24-8 Methyl-PEG4-methyl Fourtwo glycolether Tetraethylene glycol diMethyl ether, standard for GC,>=99.5%(GC) BIS[2-(2-METHOXYETHOXY)ETHYL] ETHER DIMETHYLTETRAGLYCOL DIMETHOXYTETRAETHYLENE GLYCOL DIMETHOXYTETRAGLYCOL methyltetraglyme200 nissanunioxmm200 Tetraethyleneglycoldimethyle TETRAETHYLENE GLYCOL DIMETHYL ETHER Tetraethylene Glycol Dimethyl Ether > TETRAETHYLENE GLYCOL DIMETHYL ETHER FOR etraglyme Me-PEG4-Me Factory Supply CAS 143-24-8 Tetraethylene Glycol Dimethyl Ether etraethylene glycol dimethyl ether 1-methoxy-2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethane Tetraethylene glycol dimethyl ether in methanol 2,5,8,11,14-PENTAOXAPENTADECANE TEGDME TETRAGLYME Tetraglyme、TEGDME、Me-PEG4-Me 143-24-8 CH3OCH2CH2O4CH3 143248 CH3OCH2CH24OCH3 C10H16D6O5 Organic Building Blocks Ethers General Use Puriss p.a. Oxygen Compounds Analytical Chromatography Product Catalog Building Blocks