GANODERIC ACID DM
- CAS No.
- 173075-45-1
- Chemical Name:
- GANODERIC ACID DM
- Synonyms
- Gaderic acid DM;GANODERIC ACID DM;(24E)-3,7-Dioxolanosta-8,24-dien-26-oic acid;Lanosta-8,24-dien-26-oic acid, 3,7-dioxo-, (24E)-;(R,E)-2-methyl-6-((5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-3,7-dioxo-2,3,4,5,6,7,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)hept-2-enoic acid
- CBNumber:
- CB5354656
- Molecular Formula:
- C30H44O4
- Molecular Weight:
- 468.67
- MDL Number:
- MFCD04039843
- MOL File:
- 173075-45-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Ganoderic Acid DM ≥98% | 34536 | 1mg | $121 |
| Ganoderic Acid DM ≥98% | 34536 | 5mg | $418 |
| Ganoderic Acid DM ≥98% | 34536 | 10mg | $774 |
| Ganoderic acid DM ≥98% | 380330 | 5mg | $877 |
| Ganoderic acid DM | FG42657 | 5mg | $778.8 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P321-P362+P364-P332+P313-P337+P313-P403+P233-P405-P501 | |||||||||
| NFPA 704 |
|
GANODERIC ACID DM price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 34536 | Ganoderic Acid DM ≥98% | 173075-45-1 | 1mg | $121 | 2026-04-30 | Buy |
| Cayman Chemical | 34536 | Ganoderic Acid DM ≥98% | 173075-45-1 | 5mg | $418 | 2026-04-30 | Buy |
| Cayman Chemical | 34536 | Ganoderic Acid DM ≥98% | 173075-45-1 | 10mg | $774 | 2026-04-30 | Buy |
| Usbiological | 380330 | Ganoderic acid DM ≥98% | 173075-45-1 | 5mg | $877 | 2026-06-03 | Buy |
| Biosynth | FG42657 | Ganoderic acid DM | 173075-45-1 | 5mg | $778.8 | 2026-06-04 | Buy |
GANODERIC ACID DM Chemical Properties,Uses,Production
Uses
Ganoderic acid DM, a natural triterpenoid isolated from Ganoderma lucidum, induces DNA damage, G1 cell cycle arrest and apoptosis in human breast cancer cells. Ganoderic acid DM as a specific inhibitor of osteoclastogenesis[1][2].
Definition
ChEBI: Ganoderic acid DM is a triterpenoid.
Biological Activity
Ganoderic acid DM is a triterpenoid that has been found in G. lucidum and has diverse biological activities. 1,2,3 It inhibits 5α-reductase and HMG-CoA reductase (IC50s = 10.6 and 9.5 μM, respectively) and binds to the ligand-binding domain of the androgen receptor in a fluorescence polarization assay.1,2 Ganoderic acid suppresses osteoclastogenesis of RAW 264.7 cells when used at a concentration of 12.5 μM and is cytotoxic to K562 leukemia and PC3 prostate cancer cells (IC50s = 18.8 and 81.6 μM, respectively). It reduces ear edema induced by phorbol 12-myristate 13-acetate in mice (ID50 = 0.08 mg/ear).3
References
1.Liu, J., Shiono, J., Shimizu, K., et al.Ganoderic acid DM: Anti-androgenic osteoclastogenesis inhibitorBioorg. Med. Chem. Lett.19(8)2154-2157(2009) 2.Wang, K., Bao, L., Xiong, W., et al.Lanostane triterpenes from the Tibetan medicinal mushroom Ganoderma leucocontextum and their inhibitory effects on HMG-CoA reductase and αglucosidaseJ. Nat. Prod.78(8)1977-1989(2015) 3.Akihisa, T., Nakamura, Y., Tagata, M., et al.Anti-inflammatory and anti-tumor-promoting effects of triterpene acids and sterols from the fungus Ganoderma lucidumChem. Biodivers.4(2)224-231(2007)
GANODERIC ACID DM Preparation Products And Raw materials
Raw materials
Preparation Products
GANODERIC ACID DM Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +86-18080483897 | sales@biopurify.com | China | 4616 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1922 | 58 |
| Labnetwork lnc. | +86-27-50766799 +86-18062016861 | contact@labnetwork.com | China | 19981 | 58 |
| Nanjing Doge Biomedical Technology Co., Ltd | +86-25-58227606 +86-15305155328 | sales@dogechemical.com | China | 4124 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; | support@targetmol.com | United States | 38999 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +86-18621343501 | product@acmec-e.com | China | 33301 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 50108 | 58 | |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40048 | 58 |
| Mensura Group Limited | 18780014153 | 1058503172@qq.com | China | 2900 | 58 |
| Chembest Research Laboratories Limited | 021-20908456 | sales@BioChemBest.com | China | 5996 | 61 |
View Lastest Price from GANODERIC ACID DM manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-02-24 | Ganoderic acid DM
173075-45-1
|
5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. |
-
- Ganoderic acid DM
173075-45-1
- $0.00
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
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