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5-(4-HYDROXYPHENYL)-5-PHENYLHYDANTOIN

CAS No.
2784-27-2
Chemical Name:
5-(4-HYDROXYPHENYL)-5-PHENYLHYDANTOIN
Synonyms
4-hydroxyphenytoin;NSC 156081;hydroxyphenytoin;p-hydroxyphenytoin;4-Hydroxydiphenylhy;para-hydroxyphenytoin;hydroxydiphenylhydantoin;4-hydroxydiphenylhydantoin;p-hydroxydiphenylhydantoin;5--5-phenyl-d5-hydantoin-13C3
CBNumber:
CB5355815
Molecular Formula:
C15H12N2O3
Molecular Weight:
268.27
MDL Number:
MFCD00005262
MOL File:
2784-27-2.mol
MSDS File:
SDS
Last updated:2026-05-28 05:35:58

5-(4-HYDROXYPHENYL)-5-PHENYLHYDANTOIN Properties

Melting point >300 °C(lit.)
Boiling point 411.43°C (rough estimate)
Density 1.1992 (rough estimate)
refractive index 1.5906 (estimate)
solubility soluble50mg/mL, clear, colorless to faintly yellow (DMF:MeOH(2:1))
form Solid
pka 8.37±0.10(Predicted)
color White to Off-White
Water Solubility 36mg/L(37 ºC)
InChI 1S/C15H12N2O3/c18-12-8-6-11(7-9-12)15(10-4-2-1-3-5-10)13(19)16-14(20)17-15/h1-9,18H,(H2,16,17,19,20)
InChIKey XEEDURHPFVXALT-UHFFFAOYSA-N
SMILES Oc1ccc(cc1)C2(NC(=O)NC2=O)c3ccccc3
FDA UNII L42OQX7ZQY
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE dust mask type N95 (US), Eyeshields, Gloves
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  2
RTECS  MU2485000
Storage Class 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

5-(4-HYDROXYPHENYL)-5-PHENYLHYDANTOIN price More Price(20)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 161543 5-(4-Hydroxyphenyl)-5-phenylhydantoin 98% 2784-27-2 1g $145 2023-06-20 Buy
Matrix Scientific 156061 5-(4-Hydroxyphenyl)-5-phenylimidazolidine-2,4-dione 2784-27-2 1.00g $120 2026-05-18 Buy
aablocks AA00BCVP 5-(4-Hydroxyphenyl)-5-phenylimidazolidine-2,4-dione 98% 2784-27-2 100mg $34 2026-05-28 Buy
aablocks AA00BCVP 5-(4-Hydroxyphenyl)-5-phenylimidazolidine-2,4-dione 98% 2784-27-2 250mg $59 2026-05-28 Buy
aablocks AA00BCVP 5-(4-Hydroxyphenyl)-5-phenylimidazolidine-2,4-dione 95% 2784-27-2 1g $174 2026-05-28 Buy
Product number Packaging Price Buy
161543 1g $145 Buy
156061 1.00g $120 Buy
AA00BCVP 100mg $34 Buy
AA00BCVP 250mg $59 Buy
AA00BCVP 1g $174 Buy

5-(4-HYDROXYPHENYL)-5-PHENYLHYDANTOIN Chemical Properties,Uses,Production

Uses

5-(4-Hydroxyphenyl)-5-phenylhydantoin was used in enantiomeric separation of chiral pharmaceuticals using a teicoplanin chiral stationary phase by aqueous and non-aqueous packed capillary electrochromatography. It was used as internal standard in determination of phenylbutazone and its metabolite oxyphenbutazone in human plasma by GLC.

Definition

ChEBI: A imidazolidine-2,4-dione that consists of hydantoin bearing phenyl and 4-hydroxyphenyl substituents at position 5.

General Description

5-(4-Hydroxyphenyl)-5-phenylhydantoin is the major metabolite of phenytoin.

5-(4-HYDROXYPHENYL)-5-PHENYLHYDANTOIN Preparation Products And Raw materials

Raw materials

Preparation Products

5-(4-HYDROXYPHENYL)-5-PHENYLHYDANTOIN Suppliers

Global( 34)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Clearsynth Labs Limited +91-22-26355700 info@clearsynth.com India 9656 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Aikon International Limited 025-58859352 13913916777 dt3@aikonchem.com China 15490 58
Tianjin heowns Biochemical Technology Co., Ltd. 400-6387771-6039 18920764717 sales@heowns.com China 24636 60
Nanjing Haolv Biotechnology Co.,Ltd 025-84622273 17361806303 kexin.zhou@haolvbiotech.com China 3009 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44871 58
Yancheng Tongming Biotechnology Co., Ltd. 15195160625 2863565288@qq.com China 5178 58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd 029-029-81120477 17792793610 1033@dideu.com China 9990 58
2,4-Imidazolidinedione, 5-(4-hydroxyphenyl)-5-phenyl- 2,4-Imidazolidinedione, 5-(4-hydroxyphenyl)-5-phenyl- (9CI) 2,4-Imidazolidinedione, 5-(4-hydroxyphenyl)-5-phenyl-, (.+-.)- 4-Hydroxydiphenylhy (Hydroxyphenyl)phenylhydantoin 5-(para-Hydroxyphenyl)-5-phenylhydantoin (p-hydroxyphenyl)phenylhydantoin 4-hydroxydiphenylhydantoin 5-(4-hydroxyphenyl)-5-phenyl-4-imidazolidinedione 5-(p-hydroxyphenyl)-5-phenyl-hydantoi 5-(p-hydroxyphenyl)-5-phenylhydantoin 5-p-hydroxyphenyl-5-phenylhydantoin 5-(4-Hydroxyphenyl)-5-phenylhydantoin 98% hydroxydiphenylhydantoin hydroxyphenytoin para-hydroxyphenytoin p-hydroxydiphenylhydantoin p-hydroxyphenytoin 5-(4-hydroxyphenyl)-5-phenylimidazolidine-2,4-dione 5--5-phenyl-d5-hydantoin-13C3 NSC 156081 5-Phenyl-5-(4-hydroxyphenyl)imidazolidine-2,4-dione 4-Hydroxyphenytoin (5- (4-Hydroxyphenyl)-5-phenylhydantoin) 5-(4-Hydroxyphenyl)-5-phenylhydantoin 4-Hydroxyphenytoin (5-(4-Hydroxyphenyl)-5-phenylhydantoin) 0.1 mg/ml in Methanol 4-hydroxyphenytoin 2784-27-2 Building Blocks Imidazolines/Imidazolidines Heterocyclic Building Blocks Building Blocks Heterocyclic Building Blocks Imidazolines/Imidazolidines