Prednisone 21-acetate
- CAS No.
- 125-10-0
- Chemical Name:
- Prednisone 21-acetate
- Synonyms
- Ferr;nisone;Cblconin;d-Corlin;delcortin;deltalone;delta-corlin;PREDNISONE ACETATE;Prendnisone acetate;Prednisone 21-acetat
- CBNumber:
- CB5360752
- Molecular Formula:
- C23H28O6
- Molecular Weight:
- 400.46
- MDL Number:
- MFCD00200229
- MOL File:
- 125-10-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Prednisone Acetate | P2955 | 1G | $61 |
| Prednisone Acetate | P2955 | 5G | $222 |
| Prednisone acetate 99.96%(Mayvarybetweenbatches) | orb1298969 | 200mg | $70 |
| Prednisone acetate 99.96%(Mayvarybetweenbatches) | orb1298969 | 1mlx10mM(inDMSO) | $90 |
| Prednisone acetate 99.96%(Mayvarybetweenbatches) | orb1298969 | 1g | $90 |
| More product size | |||
| Melting point | 240-242°C (dec.) |
|---|---|
| alpha | D25 +186° (dioxane) |
| Boiling point | 582.0±50.0 °C(Predicted) |
| Density | 1.28±0.1 g/cm3(Predicted) |
| storage temp. | Refrigerator |
| solubility | Chloroform (Slightly), Dioxane (Sparingly), DMSO (Slightly), Methanol (Slightly) |
| pka | 12.31±0.60(Predicted) |
| form | Solid |
| color | White to Off-White |
| Water Solubility | 23mg/L(25 ºC) |
| InChIKey | MOVRKLZUVNCBIP-RFZYENFJSA-N |
| SMILES | C1(=O)C=C2[C@](C)(C=C1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1=O)(C)[C@@](O)(C(=O)COC(C)=O)CC3)CC2 |
| CAS DataBase Reference | 125-10-0(CAS DataBase Reference) |
| FDA UNII | OU93QEL83U |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H361-H373 |
| Precautionary statements | P201-P202-P281-P308+P313-P405-P501-P260-P314-P501 |
| REACH Registrations | Active |
Prednisone 21-acetate price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | P2955 | Prednisone Acetate | 125-10-0 | 1G | $61 | 2026-04-30 | Buy |
| TCI Chemical | P2955 | Prednisone Acetate | 125-10-0 | 5G | $222 | 2026-04-30 | Buy |
| Biorbyt Ltd | orb1298969 | Prednisone acetate 99.96%(Mayvarybetweenbatches) | 125-10-0 | 200mg | $70 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1298969 | Prednisone acetate 99.96%(Mayvarybetweenbatches) | 125-10-0 | 1mlx10mM(inDMSO) | $90 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1298969 | Prednisone acetate 99.96%(Mayvarybetweenbatches) | 125-10-0 | 1g | $90 | 2026-05-06 | Buy |
Prednisone 21-acetate Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
Adrenocortical steroid antiinflammatory.
Definition
ChEBI: Cortancyl is a steroid ester, a 20-oxo steroid, an acetate ester, a 17alpha-hydroxy steroid, an 11-oxo steroid, a 3-oxo-Delta(1),Delta(4)-steroid and a tertiary alpha-hydroxy ketone. It is functionally related to a prednisone.
in vivo
Prednisone acetate (5 mg/kg, Intragastric gavage, once a day for 4 weeks) induces hippocampal LTP impairment by causing neuronal lesions in the dentate gyrus, which reduced glutamic acid (Glu) and NMDAR2A, and impaired spatial memory in Hippocampal LTP impairment model mice[1].
Prednisone acetate (6 mg/kg, gavage, once a day for 15 days) reduces ocular and peripheral inflammatory responses and restores Th1/Th2 and Th17/Treg immune homeostasis through orchestrating the Notch signaling pathway in Experimental autoimmune uveitis (EAU) rats[2].
| Animal Model: | C57BL/6 mice [1] |
| Dosage: | 5 mg/kg |
| Administration: | Intragastric gavage (i.g.) |
| Result: | Significantly failed to gain weight. Decreased the population spike (%) after high-frequency stimulation. Reduced the crossing times compared with the control group. Resulted in the impairment of memory, and caused a trend of more serious impairment. Reduced the levels of Glu and gamma-aminobutyric acid (GABA) in the hippocampus. Reduced the expressions of N-methyl-D-aspartate receptors in the hippocampus. |
| Animal Model: | Experimental autoimmune uveitis [2] |
| Dosage: | 6 mg/kg |
| Administration: | gavage |
| Result: | Showed fewer manifestations in eyes from day 9 after immunization. Reduced the inflammation in EAU rats. Bound with the pocket of Notch signaling-related molecules with good affinity. Exhibited anti-inflammatory effects through inhibiting Notch signaling activation. Decreased Th1, Th17 and increased Th2, Treg frequencies in EAU. |
IC 50
IL-17; IL-10; IL-4
Prednisone 21-acetate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Kangcang new material Technology Co., LTD | +8615713292910 | Nancy@kangcang.com.cn | China | 341 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618092446649 | sarah@tnjone.com | China | 1143 | 58 |
| Henan Suikang Pharmaceutical Co.,Ltd. | +86-18239973690 | sales@suikangpharm.com | China | 311 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21588 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 | info@tnjchem.com | China | 2988 | 55 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3619 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29817 | 58 |
| Cangzhou Wanyou New Material Technology Co.,Ltd | 18631714998 | sales@czwytech.com | CHINA | 904 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 | sales@amoychem.com | China | 6369 | 58 |
| Hebei shuoxi biotechnology co. LTD | +8613081092107 | CHINA | 964 | 58 |
View Lastest Price from Prednisone 21-acetate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-05-11 | Prednisone acetate
125-10-0
|
US $41.00 / mg | 99.96% | 10g | TargetMol Chemicals Inc. | ||
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2025-04-15 | Prednisone 21-acetate
125-10-0
|
US $0.00-0.00 / kg | 1kg | 99.0% | 1tons | Henan Suikang Pharmaceutical Co.,Ltd. | |
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2025-04-02 | Prednisone Acetate
125-10-0
|
US $0.00 / kg | 1kg | 99% | 20tons | Shaanxi TNJONE Pharmaceutical Co., Ltd |
-

- Prednisone acetate
125-10-0
- US $41.00 / mg
- 99.96%
- TargetMol Chemicals Inc.
-

- Prednisone 21-acetate
125-10-0
- US $0.00-0.00 / kg
- 99.0%
- Henan Suikang Pharmaceutical Co.,Ltd.
-

- Prednisone Acetate
125-10-0
- US $0.00 / kg
- 99%
- Shaanxi TNJONE Pharmaceutical Co., Ltd
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