ChemicalBook >> CAS DataBase List >>Prednisone 21-acetate
Prednisone 21-acetate
- CAS No.
- 125-10-0
- Chemical Name:
- Prednisone 21-acetate
- Synonyms
- PREDNISONE ACETATE;Prendnisone acetate;Ferr;nisone;Cblconin;d-Corlin;delcortin;deltalone;delta-corlin;Prednisone 21-acetat
- CBNumber:
- CB5360752
- Molecular Formula:
- C23H28O6
- Molecular Weight:
- 400.46
- MDL Number:
- MFCD00200229
- MOL File:
- 125-10-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-08-20 20:20:01
| Melting point | 240-242°C (dec.) |
|---|---|
| alpha | D25 +186° (dioxane) |
| Boiling point | 582.0±50.0 °C(Predicted) |
| Density | 1.28±0.1 g/cm3(Predicted) |
| storage temp. | Refrigerator |
| solubility | Chloroform (Slightly), Dioxane (Sparingly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 12.31±0.60(Predicted) |
| color | White to Off-White |
| Water Solubility | 23mg/L(25 ºC) |
| InChIKey | MOVRKLZUVNCBIP-RFZYENFJSA-N |
| SMILES | C1(=O)C=C2[C@](C)(C=C1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1=O)(C)[C@@](O)(C(=O)COC(C)=O)CC3)CC2 |
| CAS DataBase Reference | 125-10-0(CAS DataBase Reference) |
| FDA UNII | OU93QEL83U |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H361-H373 |
| Precautionary statements | P201-P202-P281-P308+P313-P405-P501-P260-P314-P501 |
| REACH Registrations | Active |
Prednisone 21-acetate price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | P2955 | Prednisone Acetate | 125-10-0 | 1G | $61 | 2026-04-30 | Buy |
| TCI Chemical | P2955 | Prednisone Acetate | 125-10-0 | 5G | $222 | 2026-04-30 | Buy |
| Usbiological | 019921 | Prednisone 21-Acetate | 125-10-0 | 100mg | $403 | 2026-06-03 | Buy |
| Biosynth | FP27136 | Prednisone 21-acetate | 125-10-0 | 5g | $181.45 | 2026-06-04 | Buy |
| Biosynth | FP27136 | Prednisone 21-acetate | 125-10-0 | 10g | $272.1 | 2026-06-04 | Buy |
Prednisone 21-acetate Chemical Properties, Uses, Production
Chemical Properties
White Solid
Uses
Adrenocortical steroid antiinflammatory.
Definition
ChEBI: Cortancyl is a steroid ester, a 20-oxo steroid, an acetate ester, a 17alpha-hydroxy steroid, an 11-oxo steroid, a 3-oxo-Delta(1),Delta(4)-steroid and a tertiary alpha-hydroxy ketone. It is functionally related to a prednisone.
in vivo
Prednisone acetate (5 mg/kg, Intragastric gavage, once a day for 4 weeks) induces hippocampal LTP impairment by causing neuronal lesions in the dentate gyrus, which reduced glutamic acid (Glu) and NMDAR2A, and impaired spatial memory in Hippocampal LTP impairment model mice[1].
Prednisone acetate (6 mg/kg, gavage, once a day for 15 days) reduces ocular and peripheral inflammatory responses and restores Th1/Th2 and Th17/Treg immune homeostasis through orchestrating the Notch signaling pathway in Experimental autoimmune uveitis (EAU) rats[2].
| Animal Model: | C57BL/6 mice [1] |
| Dosage: | 5 mg/kg |
| Administration: | Intragastric gavage (i.g.) |
| Result: | Significantly failed to gain weight. Decreased the population spike (%) after high-frequency stimulation. Reduced the crossing times compared with the control group. Resulted in the impairment of memory, and caused a trend of more serious impairment. Reduced the levels of Glu and gamma-aminobutyric acid (GABA) in the hippocampus. Reduced the expressions of N-methyl-D-aspartate receptors in the hippocampus. |
| Animal Model: | Experimental autoimmune uveitis [2] |
| Dosage: | 6 mg/kg |
| Administration: | gavage |
| Result: | Showed fewer manifestations in eyes from day 9 after immunization. Reduced the inflammation in EAU rats. Bound with the pocket of Notch signaling-related molecules with good affinity. Exhibited anti-inflammatory effects through inhibiting Notch signaling activation. Decreased Th1, Th17 and increased Th2, Treg frequencies in EAU. |
IC 50
IL-17; IL-10; IL-4
Prednisone 21-acetate Preparation Products And Raw materials
Raw materials
Preparation Products
Global Suppliers ( 374)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Zenuo Biopharmaceutical Technology Co., Ltd | 027-87781970 15172508891 | 1505560767@qq.com | China | 132 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| TAIYUAN RHF CO.,LTD. | +86 351 7031519 | sales@RHFChem.com | China | 2334 | 56 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| XiaoGan ShenYuan ChemPharm co,ltd | 15527621225; 15527621225 | 1791901229@qq.com | China | 6741 | 52 |
| BioBioPha Co., Ltd. | 0871-65217109 | y.liu@mail.biobiopha.com | China | 5641 | 65 |
| Guangzhou Isun Pharmaceutical Co., Ltd | 020-39119399 18927568969 | isunpharm@qq.com | China | 4773 | 55 |
| Nanjing Sunlida Biological Technology Co., Ltd. | 025-57798810 18652991625 | sales@sunlidabio.com | China | 3223 | 55 |
View Latest Price from Prednisone 21-acetate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-01 | Prednisone Acetate
125-10-0
|
1kg | 99% | 20tons | Shaanxi TNJONE Pharmaceutical Co., Ltd | ||
 |
2026-08-20 | Prednisone acetate
125-10-0
|
$41.00 | 99.96% | 10g | TargetMol Chemicals Inc. | ||
 |
2025-04-15 | Prednisone 21-acetate
125-10-0
|
1kg | 99.0% | 1tons | Henan Suikang Pharmaceutical Co.,Ltd. |
-
- Prednisone Acetate
125-10-0
- $0.00
- 99%
- Shaanxi TNJONE Pharmaceutical Co., Ltd
-
- Prednisone acetate
125-10-0
- $41.00
- 99.96%
- TargetMol Chemicals Inc.
-
- Prednisone 21-acetate
125-10-0
- 99.0%
- Henan Suikang Pharmaceutical Co.,Ltd.
125-10-0 (Prednisone 21-acetate) Related Search:
17 ALPHA,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE-21-ACETATE
1-DEHYDROCORTISONE ACETATE
1,4-PREGNADIEN-17,21-DIOL-3,11,20-TRIONE 21-ACETATE
1,4-PREGNADIEN-17ALPHA,21-DIOL-3,11,20-TRIONE 21-ACETATE
[2-[(8s,9s,10s,13s,14s,17r)-17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] acetate
Dehydrocortisone acetate
prednisone 21-acetate
17,21-Dihydroxypregna-1,4-diene-3,11,20-trione-21-acetate
17α,21-Dihydroxypregna-1,4-diene-3,11,20-trioneacetate
[2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
[2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] ethanoate
acetic acid [2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-3,11-diketo-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-keto-ethyl] ester
Prednisone 21-acetat
1-Cortisone 21-Acetate
21-(Acetyloxy)-17-hydroxy-pregna-1,4-diene-3,11,20-trione
11,20-trione,21-(acetyloxy)-17-hydroxy-pregna-4-diene-3
4-diene-3,11,20-trione,17,21-dihydroxy-pregna-21-acetate
acetic acid [2-(17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl)-2-oxoethyl] ester
Prednisone/ Prednisone Acetate
Prednisone EP Impurity E
delcortin
delta’-dehydrocortisoneacetate
delta-corlin
deltalone
nisone
ACETIC ACID 2-((8S,9S,10R,13S,14S,17R)-17-HYDROXY-10,13-DIMETHYL-3,11-DIOXO-6,7,8,9,10,11,12,13,14,15,16,17-DODECAHYDRO-3H-CYCLOPENTA[A]PHENANTHREN-17-YL)-2-OXO-ETHYL ESTER
21-Acetoxy-17α-hydroxypregna-1,4-diene-3,11,20-trione
Ferr
Pregna-1,4-diene-3,11,20-trione,21-(acetyloxy)-17-hydroxy-
Cblconin
Prednisone EP Impurity E (Prednisone 21-Acetate)
hot selling Prednisone 21-acetate
Prednisone 21-acetate USP/EP/BP
d-Corlin
Prednisone Impurity 6
Cortancyl (Prednisone 21-acetate)
21-Acetoxy-17a-hydroxypregna-1,4-diene-3,11,20-trione (Prednisone Acetate)
Prednisone 21-acetate / Dehydrocortisone acetate
Alitretinoin Impurity 22
Prednisolone Impurity 32
Prednisone acetate, Glucocorticoid
Prednisone acetate, 10 mM in DMSO
Prednisone acetate (Standard)
PREDNISONE ACETATE
Prendnisone acetate
125-10-0
125-10-2
120-24-8
C23H28O6
40046
Intermediates & Fine Chemicals
Pharmaceuticals
Steroids
125-10-0
