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Prednisone 21-acetate

CAS No.
125-10-0
Chemical Name:
Prednisone 21-acetate
Synonyms
Ferr;nisone;Cblconin;d-Corlin;delcortin;deltalone;delta-corlin;PREDNISONE ACETATE;Prendnisone acetate;Prednisone 21-acetat
CBNumber:
CB5360752
Molecular Formula:
C23H28O6
Molecular Weight:
400.46
MDL Number:
MFCD00200229
MOL File:
125-10-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-12 09:14:19
Product description Number Pack Size Price
Prednisone Acetate P2955 1G $61
Prednisone Acetate P2955 5G $222
Prednisone acetate 99.96%(Mayvarybetweenbatches) orb1298969 200mg $70
Prednisone acetate 99.96%(Mayvarybetweenbatches) orb1298969 1mlx10mM(inDMSO) $90
Prednisone acetate 99.96%(Mayvarybetweenbatches) orb1298969 1g $90
More product size

Prednisone 21-acetate Properties

Melting point 240-242°C (dec.)
alpha D25 +186° (dioxane)
Boiling point 582.0±50.0 °C(Predicted)
Density 1.28±0.1 g/cm3(Predicted)
storage temp. Refrigerator
solubility Chloroform (Slightly), Dioxane (Sparingly), DMSO (Slightly), Methanol (Slightly)
pka 12.31±0.60(Predicted)
form Solid
color White to Off-White
Water Solubility 23mg/L(25 ºC)
InChIKey MOVRKLZUVNCBIP-RFZYENFJSA-N
SMILES C1(=O)C=C2[C@](C)(C=C1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1=O)(C)[C@@](O)(C(=O)COC(C)=O)CC3)CC2
CAS DataBase Reference 125-10-0(CAS DataBase Reference)
FDA UNII OU93QEL83U

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Warning
Hazard statements  H361-H373
Precautionary statements  P201-P202-P281-P308+P313-P405-P501-P260-P314-P501
REACH Registrations Active

Prednisone 21-acetate price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical P2955 Prednisone Acetate 125-10-0 1G $61 2026-04-30 Buy
TCI Chemical P2955 Prednisone Acetate 125-10-0 5G $222 2026-04-30 Buy
Biorbyt Ltd orb1298969 Prednisone acetate 99.96%(Mayvarybetweenbatches) 125-10-0 200mg $70 2026-05-06 Buy
Biorbyt Ltd orb1298969 Prednisone acetate 99.96%(Mayvarybetweenbatches) 125-10-0 1mlx10mM(inDMSO) $90 2026-05-06 Buy
Biorbyt Ltd orb1298969 Prednisone acetate 99.96%(Mayvarybetweenbatches) 125-10-0 1g $90 2026-05-06 Buy
Product number Packaging Price Buy
P2955 1G $61 Buy
P2955 5G $222 Buy
orb1298969 200mg $70 Buy
orb1298969 1mlx10mM(inDMSO) $90 Buy
orb1298969 1g $90 Buy

Prednisone 21-acetate Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

Adrenocortical steroid antiinflammatory.

Definition

ChEBI: Cortancyl is a steroid ester, a 20-oxo steroid, an acetate ester, a 17alpha-hydroxy steroid, an 11-oxo steroid, a 3-oxo-Delta(1),Delta(4)-steroid and a tertiary alpha-hydroxy ketone. It is functionally related to a prednisone.

in vivo

Prednisone acetate (5 mg/kg, Intragastric gavage, once a day for 4 weeks) induces hippocampal LTP impairment by causing neuronal lesions in the dentate gyrus, which reduced glutamic acid (Glu) and NMDAR2A, and impaired spatial memory in Hippocampal LTP impairment model mice[1].
Prednisone acetate (6 mg/kg, gavage, once a day for 15 days) reduces ocular and peripheral inflammatory responses and restores Th1/Th2 and Th17/Treg immune homeostasis through orchestrating the Notch signaling pathway in Experimental autoimmune uveitis (EAU) rats[2].

Animal Model:C57BL/6 mice [1]
Dosage:5 mg/kg
Administration:Intragastric gavage (i.g.)
Result:Significantly failed to gain weight. Decreased the population spike (%) after high-frequency stimulation. Reduced the crossing times compared with the control group. Resulted in the impairment of memory, and caused a trend of more serious impairment. Reduced the levels of Glu and gamma-aminobutyric acid (GABA) in the hippocampus. Reduced the expressions of N-methyl-D-aspartate receptors in the hippocampus.
Animal Model:Experimental autoimmune uveitis [2]
Dosage:6 mg/kg
Administration:gavage
Result:Showed fewer manifestations in eyes from day 9 after immunization. Reduced the inflammation in EAU rats. Bound with the pocket of Notch signaling-related molecules with good affinity. Exhibited anti-inflammatory effects through inhibiting Notch signaling activation. Decreased Th1, Th17 and increased Th2, Treg frequencies in EAU.

IC 50

IL-17; IL-10; IL-4

Prednisone 21-acetate Preparation Products And Raw materials

Global( 363)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Kangcang new material Technology Co., LTD
+8615713292910 Nancy@kangcang.com.cn China 341 58
Shaanxi TNJONE Pharmaceutical Co., Ltd
+8618092446649 sarah@tnjone.com China 1143 58
Henan Suikang Pharmaceutical Co.,Ltd.
+86-18239973690 sales@suikangpharm.com China 311 58
Henan Tianfu Chemical Co.,Ltd.
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Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418679 +8618949832763 info@tnjchem.com China 2988 55
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18017610038 zheyansh@163.com CHINA 3619 58
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29817 58
Cangzhou Wanyou New Material Technology Co.,Ltd
18631714998 sales@czwytech.com CHINA 904 58
Xiamen AmoyChem Co., Ltd
+86-86-5926051114 +8615060885618 sales@amoychem.com China 6369 58
Hebei shuoxi biotechnology co. LTD
+8613081092107 CHINA 964 58

View Lastest Price from Prednisone 21-acetate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Prednisone acetate pictures 2026-05-11 Prednisone acetate
125-10-0
US $41.00 / mg 99.96% 10g TargetMol Chemicals Inc.
Prednisone 21-acetate pictures 2025-04-15 Prednisone 21-acetate
125-10-0
US $0.00-0.00 / kg 1kg 99.0% 1tons Henan Suikang Pharmaceutical Co.,Ltd.
Prednisone Acetate pictures 2025-04-02 Prednisone Acetate
125-10-0
US $0.00 / kg 1kg 99% 20tons Shaanxi TNJONE Pharmaceutical Co., Ltd

Prednisone 21-acetate Spectrum

17 ALPHA,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE-21-ACETATE 1-DEHYDROCORTISONE ACETATE 1,4-PREGNADIEN-17,21-DIOL-3,11,20-TRIONE 21-ACETATE 1,4-PREGNADIEN-17ALPHA,21-DIOL-3,11,20-TRIONE 21-ACETATE [2-[(8s,9s,10s,13s,14s,17r)-17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] acetate Dehydrocortisone acetate prednisone 21-acetate PREDNISONE ACETATE 17,21-Dihydroxypregna-1,4-diene-3,11,20-trione-21-acetate 17α,21-Dihydroxypregna-1,4-diene-3,11,20-trioneacetate [2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate [2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxo-ethyl] ethanoate acetic acid [2-[(8S,9S,10R,13S,14S,17R)-17-hydroxy-3,11-diketo-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-keto-ethyl] ester Prednisone 21-acetat 1-Cortisone 21-Acetate 21-(Acetyloxy)-17-hydroxy-pregna-1,4-diene-3,11,20-trione 11,20-trione,21-(acetyloxy)-17-hydroxy-pregna-4-diene-3 4-diene-3,11,20-trione,17,21-dihydroxy-pregna-21-acetate acetic acid [2-(17-hydroxy-10,13-dimethyl-3,11-dioxo-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl)-2-oxoethyl] ester Prednisone/ Prednisone Acetate Prednisone EP Impurity E delcortin delta’-dehydrocortisoneacetate delta-corlin deltalone nisone ACETIC ACID 2-((8S,9S,10R,13S,14S,17R)-17-HYDROXY-10,13-DIMETHYL-3,11-DIOXO-6,7,8,9,10,11,12,13,14,15,16,17-DODECAHYDRO-3H-CYCLOPENTA[A]PHENANTHREN-17-YL)-2-OXO-ETHYL ESTER 21-Acetoxy-17α-hydroxypregna-1,4-diene-3,11,20-trione Ferr Pregna-1,4-diene-3,11,20-trione,21-(acetyloxy)-17-hydroxy- Cblconin Prednisone EP Impurity E (Prednisone 21-Acetate) hot selling Prednisone 21-acetate Prednisone 21-acetate USP/EP/BP d-Corlin Prednisone Impurity 6 Cortancyl (Prednisone 21-acetate) 21-Acetoxy-17a-hydroxypregna-1,4-diene-3,11,20-trione (Prednisone Acetate) Prednisone 21-acetate / Dehydrocortisone acetate Prendnisone acetate Alitretinoin Impurity 22 Prednisolone Impurity 32 Prednisone acetate, Glucocorticoid Prednisone acetate, 10 mM in DMSO Prednisone acetate (Standard) 125-10-0 125-10-2 C23H28O6 40046 Intermediates & Fine Chemicals Pharmaceuticals Steroids 125-10-0