FENOVERINE
- CAS No.
- 37561-27-6
- Chemical Name:
- FENOVERINE
- Synonyms
- FENOVERINE;Spasmopriv;Fenoverine D8;3-chloro-3-oxopropanoic acid ethyl ester;10-[(4-Piperonyl-1-piperazinyl)acetyl]-10H-phenothiazine;Ethanone, 2-[4-(1,3-benzodioxol-5-ylmethyl)-1-piperazinyl]-1-(10H-phenothiazin-10-yl)-
- CBNumber:
- CB5362347
- Molecular Formula:
- C26H25N3O3S
- Molecular Weight:
- 459.56
- MDL Number:
- MFCD00865242
- MOL File:
- 37561-27-6.mol
- MSDS File:
- SDS
| Melting point | 141-142° |
|---|---|
| Boiling point | 671.8±55.0 °C(Predicted) |
| Density | 1.343±0.06 g/cm3(Predicted) |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| pka | 6.47±0.10(Predicted) |
| form | Solid |
| color | Pale Beige to Beige |
| Stability | Hygroscopic |
| FDA UNII | N274ZQ6PZJ |
| ATC code | A03AX05 |
SAFETY
Risk and Safety Statements
| Toxicity | LD50 in mice (g/kg): ~1.50 orally, ~2.50 i.p. (Buzas, Pierre) |
|---|
FENOVERINE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-F248898-50MG | Fenoverine | 37561-27-6 | 50mg | $142 | 2026-06-03 | Buy |
| TRC | TRC-F248898-500MG | Fenoverine | 37561-27-6 | 500mg | $981 | 2026-06-03 | Buy |
| ChemScene | CS-0375172 | Fenoverine-d8 98.88% | 100??g | $97 | 2026-06-04 | Buy | |
| ChemScene | CS-0375172 | Fenoverine-d8 98.88% | 1mg | $390 | 2026-06-04 | Buy | |
| ChemScene | CS-0375172 | Fenoverine-d8 98.88% | 5mg | $975 | 2026-06-04 | Buy |
FENOVERINE Chemical Properties, Uses, Production
Originator
Spasmopriv,Paillusseau
Uses
Fenoverine is a colon-specific multi particulate drug. Also, it is an antispasmodic drug which inhibits contraction of smooth muscle. It is derived from Phenothiazine (P318040), which is a key component of antipsychotic and antihistaminic drugs.
Definition
ChEBI: Fenoverine is a member of phenothiazines.
Manufacturing Process
To a hot solution 199.3 g (0.1 mol) of phenothiazine in 2 L of dry benzene
was added a little quantity of bromine and then were added dropwise 136 g
(0.1 mol) of chloroacetyle chloride. Then a mixture was refluxed for 5 hours.
After cooling the mixture was concentrated in vacuo. Product was dissolved at
reflux in ethanol absolute and filtered. At room temperature was crystallized
chloracetyl-10-phenothiazine with 123°C; yield 242 g.
A mixture of 13.8 g (0.05 mol) of chloracetyl-10-phenothiazine, 11.8 g (0.05
mol) of piperonyl-1-piperazine and 3.9 g (0.05 mol) of pyridine in 200 ml of
dry toluene was refluxed for 3 hours. Then the solution was cooled and
filtered. The filtrate was concentrated. The crystals of 10-((4-piperonyl-1-
piperazinyl)acetyl)phenothiazine was recrystallized from isopropylic ether; M.P.
141-142°C; yield 67%.
Therapeutic Function
Spasmolytic
FENOVERINE Preparation Products And Raw materials
FENOVERINE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| LGM Pharma | 1-(800)-881-8210 | inquiries@lgmpharma.com | United States | 2110 | 70 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Shanghai Dongyang Biotechnology Co., Ltd. | 0512-13601744364 13601744364 | chemsharker@126.com | China | 1160 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Cdreamlab (Hubei) Technology Co., LTD | 0717-6300888 18062399888 | service@cdreamlab.com | China | 296 | 58 |
| Z-trans Biochemistry Technology (Suzhou) Co.,Ltd | 0512-66317708 13372112871 | huijuan@zitrans.cn | China | 2260 | 58 |
| Cdreamlab (Hubei) Technology Co., LTD | 18062399888; 18062399888 | service@cdreamlab.com | China | 129 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Guangzhou Reullei Pharmaceutical Technology Co., Ltd， | 13660253774 | joe.yang@reullei.com | China | 4989 | 58 |
| Shanghai Amole Biotechnology Co., Ltd. | 13370042665 18916960931 | 2596183085@qq.com | China | 17234 | 58 |
View Latest Price from FENOVERINE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-10 | Fenoverine
37561-27-6
|
$496.00-1180.00 | 98.34% | 10g | TargetMol Chemicals Inc. |
-
- Fenoverine
37561-27-6
- $496.00-1180.00
- 98.34%
- TargetMol Chemicals Inc.
