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CAPSANTHIN

CAS No.
465-42-9
Chemical Name:
CAPSANTHIN
Synonyms
Paprika Red;Yellow corn;CAPSANTHIN/CAPSORUBIN;E 160c;C08584;Chili Red;CAPSANTHIN;CAPSORUBINE;Capsanthine;CAPSANTHIN tlc
CBNumber:
CB5380132
Molecular Formula:
C40H56O3
Molecular Weight:
584.87
MDL Number:
MFCD31726206
MOL File:
465-42-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-20 15:45:16

CAPSANTHIN Properties

Melting point 177-178℃
alpha Cd +36° (chloroform)
Boiling point 581.82°C (rough estimate)
Density 1.012
refractive index 1.4960 (estimate)
storage temp. -20°C
solubility Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
form Solid
pka 14.85±0.60(Predicted)
color Dark Red to Very Dark Brown
optical activity 〔α〕Cd +36 (CHCl3)
λmax λ: 467-471 nm Amax
Merck 14,1769
Henry's Law Constant 3.4×102 mol/(m3Pa) at 25℃, HSDB (2015)
Stability Light Sensitive, Temperature Sensitive
Cosmetics Ingredients Functions COLORANT
InChIKey VYIRVAXUEZSDNC-RDJLEWNRSA-N
SMILES CC(/C=C/C1=C(C)C[C@@H](O)CC1(C)C)=C\C=C\C(C)=C\C=C\C=C(C)\C=C\C=C(\C=C\C([C@@]2(C)C(C)(C)C[C@H](O)C2)=O)C
LogP 9.467 (est)
EWG's Food Scores 1
FDA UNII 420NY1J57N
UNSPSC Code 12352202
NACRES NA.32

SAFETY

Risk and Safety Statements

WGK Germany  3
HS Code  2914.50.3000
Storage Class 11 - Combustible Solids
Hazardous Substances Data 465-42-9(Hazardous Substances Data)

CAPSANTHIN price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 94863 Capsanthin analytical standard 465-42-9 1MG $1320 2026-04-30 Buy
TCI Chemical C0781 Capsanthin (=Paprika Extract)(Vegetable oil solution) 465-42-9 25g $77 2026-04-30 Buy
Cayman Chemical 31202 Capsanthin ≥98% 465-42-9 500μg $659 2026-04-30 Buy
Cayman Chemical 31202 Capsanthin ≥98% 465-42-9 1mg $989 2026-04-30 Buy
Cayman Chemical 18264 Capsanthin 465-42-9 10mg $45 2021-12-16 Buy
Product number Packaging Price Buy
94863 1MG $1320 Buy
C0781 25g $77 Buy
31202 500μg $659 Buy
31202 1mg $989 Buy
18264 10mg $45 Buy

CAPSANTHIN Chemical Properties,Uses,Production

Description

Capsanthin is the major colouring compounds contained in the Paprika oleoresin, which is a kind of oil-soluble extract isolated from the fruits Capsicum annuum or Capsicum frutescens, and is a colouring and/or flavouring in food products. As a pink pigment, Capsanthin is very abundant in peppers, accounting for 60% of the proportions of all flavonoids in the peppers. It has antioxidant properties, being able to help the body to scavenge the free radicals as well as inhibiting the growth of cancer cells.

References

http://www.botanical-online.com/english/capsanthin_properites.htm
https://en.wikipedia.org/wiki/Paprika_oleoresin

Description

Capsanthin is a carotenoid that has been found in C. annuum and has diverse biological activities. It reduces hydrogen peroxide-induced production of reactive oxygen species (ROS) and phosphorylation of ERK and p38 and prevents hydrogen peroxide-induced inhibition of gap junction intercellular communication in WB-F344 rat liver epithelial cells. Capsanthin (0.2 mg/animal) reduces the number of colonic aberrant crypt foci and preneoplastic lesions in a rat model of N-methylnitrosourea-induced colon carcinogenesis. It also reduces ear edema in a mouse model of inflammation induced by phorbol 12-myristate 13-acetate (TPA; ).

Chemical Properties

The main components are capsaicin and capsaicin yuhongin, orange-red viscous liquid, paste or powder with chili odor, no spicy taste. Soluble in organic solvents such as oil and ethanol, orange red to orange red after dissolving in oil, insoluble in water. Emulsification and dispersion, heat resistance, acid resistance are good, light resistance is a little poor, stable to metal ions, strong coloring power. The maximum absorption wavelength is 470nm in acetone, the oral LD50 of mice>1.7g/kg, because it is extracted from red pepper, high safety.

Uses

Capsanthin may be used as an analytical reference standard for the quantification of the analyte in red pepper powder, red pepper fruits, paprika and oleoresin using chromatography techniques.

Uses

antineoplastic

Definition

ChEBI: Capsanthin is a carotenone. It has a role as a plant metabolite.

General Description

Capsanthin, also known as the red pepper carotenoid, is one of the major color pigments of paprika oleoresin, an oil-soluble extract, isolated from the fruits of Capsicum annum Linn or Capsicum frutescens. It is widely used as a color additive in food industries across the globe. The photoprotective effect of capsanthin protects human dermal fibroblasts against UVB induced DNA damage.

Hazard

A poison by skin contact.

Biochem/physiol Actions

Capsanthin is a potential nutraceutical, is found in green vegetables and is a constituent of paprika and asparagus. Capsanthin has been shown to exhibit anti-proliferative function.

Safety Profile

A poison by skin contact. When heated to decomposition it emits acrid smoke and irritating vapors.

Purification Methods

Possible impurities are zeaxanthin and capsorubin (below). Purify capsanthin by chromatography on a column of alumina (grade IV) and develop with 0.2% EtOH in *C6H6. It

395089-68-6
465-42-9
Synthesis of CAPSANTHIN from 2,4-Pentadienoic acid, 5-[(4R)-4-hydroxy-2,6,6-trimethyl-1-cyclohexen-1-yl]-3-methyl-, ethyl ester, (2E,4E)-

CAPSANTHIN Preparation Products And Raw materials

Global( 305)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Maya High Purity Chemicals +86 (573) 82222445 (0)18006601000 452520369 sales@maya-r.com China 11693 57
ShangHai YuanYe Biotechnology Co., Ltd. 15026964105 shyysw007@163.com China 4998 60
XI'AN KPC-CN BIOLOGICAL TECHNOLOGY CO.,LTD. 86-029-85456576 daisy_wang@vip.163.com China 292 55
TOKYO CHEMICAL INDUSTRY CO., LTD. 03-36680489 Sales-JP@TCIchemicals.com Japan 28364 80

View Lastest Price from CAPSANTHIN manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Capsanthin pictures 2026-09-01 Capsanthin
465-42-9
1kg 99% 20tons Shaanxi TNJONE Pharmaceutical Co., Ltd
CAPSANTHIN pictures 2026-03-20 CAPSANTHIN
465-42-9
$10.00 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
Capsanthin pictures 2025-04-15 Capsanthin
465-42-9
$48.00 1kg 99% 5000kg/week Hebei Zhuanglai Chemical Trading Co.,Ltd
  • Capsanthin pictures
  • Capsanthin
    465-42-9
  • $0.00
  • 99%
  • Shaanxi TNJONE Pharmaceutical Co., Ltd
  • CAPSANTHIN pictures
  • CAPSANTHIN
    465-42-9
  • $10.00
  • 99%
  • Hebei Chuanghai Biotechnology Co., Ltd
  • Capsanthin pictures
  • Capsanthin
    465-42-9
  • $48.00
  • 99%
  • Hebei Zhuanglai Chemical Trading Co.,Ltd
PAPRIKA EXTRACT BETA,KAPPA-CAROTEN-6'-ONE, 3,3'-DIHYDROXY-, (3R,3'S,5'R)- CAPSANTHIN 3,3'-DIHYDROXY-BETA,KAPPA-CAROTEN-6'-ONE Capsanthin(=paprika E 160c (3R,3'S,5'R)-3,3'-dihydroxy-beta,.kappa.-caroten-6'-one Chili Red CAPSANTHIN/CAPSORUBIN Oleoresin paprika 10-100,000 Cu CAPSORUBINE CAPSANTHIN(=PAPRIKA EXTRACT)(VEGETABLE OIL SOLUTION) CAPSANTHIN:B, |-CAROTEN-6''-ONE, 3,3''-DIHYDROXY-, (3R,3''S,5''R)-, CAPSANTHIN WITH TLC CAPSANTHIN tlc Chili red pigment (2E,4E,6E,8E,10E,12E,14E,16E,18E)-19-[(4R)-4-hydroxy-2,6,6-trimethyl-1-cyclohexenyl]-1-[(1R,4S)-4-hydroxy-1,2,2-trimethylcyclopentyl]-4,8,13,17-tetramethyl-1-nonadeca-2,4,6,8,10,12,14,16,18-nonaenone colorant capsanthin (3R,3'S)-3,3'-Dihydroxy-β,κ-carotene-6'-one (3R,3'S,5'R)-3,3'-Dihydroxy-β,κ-caroten-6'-one all-trans-Capsanthin Capsanthine Capsanthin (=Paprika Extract) C08584 CAPSANTHIN(SH)(IN CHLOROFORM) (all-E)-19-(4-Hydroxy-2,6,6-trimethyl-1-cyclohexen-1-yl)-1-(4-hydroxy-1,2,2-trimethylcyclopentyl)-4,8,13,17-tetramethyl-2,4,6,8,10,12,14,16,18-nonadecanonaen-1-one (=Paprika Extract) (Vegetable oil solution) Capsanthin  Yellow corn Oil soluble capsicum red pigment (2E,4E,6E,8E,10E,12E,14E,16E,18E)-19-[(4R)-4-hydroxy-2,6,6-trimethylcyclohexen-1-yl]-1-[(1R,4S)-4-hydroxy-1,2,2-trimethylcyclopentyl]-4,8,13,17-tetramethylnonadeca-2,4,6,8,10,12,14,16,18-nonaen-1-one Oil-soluble red pepper β,κ-Caroten-6'-one, 3,3'-dihydroxy-, (3R,3'S,5'R)- Water-soluble paprika oleoresin Capsicum red、paprika red Nicotinamide Impurity 239 Capsanthin, antioxidant Paprika Red 465-42-9 C40H56O3 Thiophenes ,Thiazolines/Thiazolidines Carotenoids