ChemicalBook >> CAS DataBase List >>1-{5-[(2,4-dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-yl}-3-(4-methylphenyl)urea

1-{5-[(2,4-dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-yl}-3-(4-methylphenyl)urea

CAS No.
428478-94-8
Chemical Name:
1-{5-[(2,4-dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-yl}-3-(4-methylphenyl)urea
Synonyms
OPREA1_650507;cyt-PTPε Inhibitor-1;Cyt-PTPε Inhibitor-1, 10 mM in DMSO;1-[5-(2,4-Dimethyl-phenoxymethyl)-[1,3,4]thiadiazol-2-yl]-3-p-tolyl-urea;1-{5-[(2,4-dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-yl}-3-(4-methylphenyl)urea;N-{5-[(2,4-dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-yl}-N'-(4-methylphenyl)urea;Urea, N-[5-[(2,4-dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-yl]-N'-(4-methylphenyl)-
CBNumber:
CB53984902
Molecular Formula:
C19H20N4O2S
Molecular Weight:
368.4527
MDL Number:
MFCD02639412
MOL File:
428478-94-8.mol
MSDS File:
SDS
Last updated:2026-07-27 17:00:41

1-{5-[(2,4-dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-yl}-3-(4-methylphenyl)urea Properties

Density 1.319±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
form Solid
pka 7.07±0.50(Predicted)
color White to off-white

1-{5-[(2,4-dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-yl}-3-(4-methylphenyl)urea price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth DSA47894 1-[5-(2,4-Dimethyl-phenoxymethyl)-[1,3,4]thiadiazol-2-yl]-3-p-tolyl-urea 428478-94-8 1mg $514.01 2026-06-04 Buy
Biosynth DSA47894 1-[5-(2,4-Dimethyl-phenoxymethyl)-[1,3,4]thiadiazol-2-yl]-3-p-tolyl-urea 428478-94-8 5mg $1670.55 2026-06-04 Buy
Biosynth DSA47894 1-[5-(2,4-Dimethyl-phenoxymethyl)-[1,3,4]thiadiazol-2-yl]-3-p-tolyl-urea 428478-94-8 10mg $2672.8 2026-06-04 Buy
Biosynth DSA47894 1-[5-(2,4-Dimethyl-phenoxymethyl)-[1,3,4]thiadiazol-2-yl]-3-p-tolyl-urea 428478-94-8 25mg $5011.5 2026-06-04 Buy
Biosynth DSA47894 1-[5-(2,4-Dimethyl-phenoxymethyl)-[1,3,4]thiadiazol-2-yl]-3-p-tolyl-urea 428478-94-8 50mg $8018.5 2026-06-04 Buy
Product number Packaging Price Buy
DSA47894 1mg $514.01 Buy
DSA47894 5mg $1670.55 Buy
DSA47894 10mg $2672.8 Buy
DSA47894 25mg $5011.5 Buy
DSA47894 50mg $8018.5 Buy

1-{5-[(2,4-dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-yl}-3-(4-methylphenyl)urea Chemical Properties, Uses, Production

Uses

cyt-PTPε Inhibitor-1 is a potent cytosolic protein tyrosine phosphatase epsilon (cyt-PTPε) inhibitor, binds to the catalytic domain of cyt-PTPε, blocks c-Src activation (dephosphorylation of c-Src), and exhibits anti-osteoclastic activity[1].

References

[1] Ku B, et al. Identification of N-(5-(phenoxymethyl)-1,3,4-thiadiazol-2-yl)acetamide derivatives as novel protein tyrosine phosphatase epsilon inhibitors exhibiting anti-osteoclastic activity. ioorg Med Chem. 2018 Oct 1;26(18):5204-5211. DOI:10.1016/j.bmc.2018.09.022

1-{5-[(2,4-dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-yl}-3-(4-methylphenyl)urea Preparation Products And Raw materials

Raw materials

Preparation Products

1-{5-[(2,4-dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-yl}-3-(4-methylphenyl)urea Suppliers

Global Suppliers ( 27)
Supplier Tel Email Country ProdList Advantage
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shanghai Rechem science Co., Ltd. 021-31433387 15618786686 sales@rechemscience.com China 2969 58
Shanghai Chaolan Chemical Technology Center QQ:65489617 13301690235 Sales@ATKchemical.com China 9699 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Shanghai Dongyang Biotechnology Co., Ltd. 0512-13601744364 13601744364 chemsharker@126.com China 1160 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Xianning Shen Lan Biomedical Research and Development Co., Ltd. 18171815831 1341138380@qq.com China 4573 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. 6206333 13167063860 anhua.mao@aladdin-e.com China 43486 58
Shandong Dayou Pharmaceutical Research and Development Co., Ltd. hanfangpharma@126.com 15165037910 hanfangpharma@126.com China 25800 58

View Latest Price from 1-{5-[(2,4-dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-yl}-3-(4-methylphenyl)urea manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Cyt-PTPε Inhibitor-1 pictures 2026-08-08 Cyt-PTPε Inhibitor-1
428478-94-8
$35.00 99.55% 10g TargetMol Chemicals Inc.
Cyt-PTPε Inhibitor-1 pictures 2026-08-08 Cyt-PTPε Inhibitor-1
428478-94-8
$35.00 99.55% 10g TargetMol Chemicals Inc.

1-{5-[(2,4-dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-yl}-3-(4-methylphenyl)urea Spectrum

1-{5-[(2,4-dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-yl}-3-(4-methylphenyl)urea N-{5-[(2,4-dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-yl}-N'-(4-methylphenyl)urea cyt-PTPε Inhibitor-1 Urea, N-[5-[(2,4-dimethylphenoxy)methyl]-1,3,4-thiadiazol-2-yl]-N'-(4-methylphenyl)- Cyt-PTPε Inhibitor-1, 10 mM in DMSO OPREA1_650507 1-[5-(2,4-Dimethyl-phenoxymethyl)-[1,3,4]thiadiazol-2-yl]-3-p-tolyl-urea 428478-94-8