3,5-Diiodo-4-hydroxybenzaldehyde
- CAS No.
- 1948-40-9
- Chemical Name:
- 3,5-Diiodo-4-hydroxybenzaldehyde
- Synonyms
- NSC 72943;AKOS B028744;6-Fluoroacetophenone;Amiodarone Impurity 46;2,6-Diiodo-4-formylphenol;4-Hydroxy-3,5-diiodbenzaldehyd;Levothyroxine Sodium Impurity f;3,5-Diiodo-4-Hydroxybenzaldhyde;3,5-Diiodo-4-Hydroxybenzadehyde;3,5-Diiodo-4-hydroxybenzaldehyde
- CBNumber:
- CB5406528
- Molecular Formula:
- C7H4I2O2
- Molecular Weight:
- 373.91
- MDL Number:
- MFCD00014670
- MOL File:
- 1948-40-9.mol
- MSDS File:
- SDS
| Melting point | 202-203°C |
|---|---|
| Boiling point | 284.1±40.0 °C(Predicted) |
| Density | 2.602±0.06 g/cm3(Predicted) |
| storage temp. | -20°C Freezer, Under Inert Atmosphere |
| solubility | Chloroform (Slightly, Sonicated), DMSO (Slightly) |
| form | Solid |
| pka | 4.89±0.23(Predicted) |
| color | White to Pale Yellow |
| Water Solubility | Insoluble in water. Sparingly soluble in chloroform and methanol. |
| Sensitive | Air & Light Sensitive |
| BRN | 1283414 |
| InChI | InChI=1S/C7H4I2O2/c8-5-1-4(3-10)2-6(9)7(5)11/h1-3,11H |
| InChIKey | WHLUEIMENHLCMY-UHFFFAOYSA-N |
| SMILES | C(=O)C1=CC(I)=C(O)C(I)=C1 |
| CAS DataBase Reference | 1948-40-9(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| HS Code | 2913000090 | |||||||||
| NFPA 704 |
|
3,5-Diiodo-4-hydroxybenzaldehyde price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | H1539 | 4-Hydroxy-3,5-diiodobenzaldehyde >97.0%(T) | 1948-40-9 | 5g | $38 | 2026-04-30 | Buy |
| TCI Chemical | H1539 | 4-Hydroxy-3,5-diiodobenzaldehyde >97.0%(T) | 1948-40-9 | 25g | $112 | 2026-04-30 | Buy |
| TRC | TRC-D455080-500MG | 3,5-Diiodo-4-hydroxybenzaldehyde | 1948-40-9 | 500mg | $65 | 2026-06-03 | Buy |
| Biosynth | FD22129 | 3,5-Diiodo-4-hydroxybenzaldehyde | 1948-40-9 | 0.01kg | $150 | 2026-06-04 | Buy |
| Biosynth | FD22129 | 3,5-Diiodo-4-hydroxybenzaldehyde | 1948-40-9 | 0.005kg | $150 | 2026-06-04 | Buy |
3,5-Diiodo-4-hydroxybenzaldehyde Chemical Properties, Uses, Production
Chemical Properties
Pale Beige Solid
Uses
3,5-Diiodo-4-hydroxybenzaldehyde (cas# 1948-40-9) is a compound useful in organic synthesis.
Synthesis
3,5-Diiodo-4-hydroxybenzaldehyde was prepared as follows: in a 100 mL round bottom flask, 4-hydroxybenzaldehyde (1.0 g, 8.19 mmol), sodium periodate (1.75 g, 8.19 mmol), and NaCl (957 mg, 16.38 mmol) were dissolved in acetic acid (30 mL). H2O (3 mL) was added at room temperature. The reaction mixture was stirred at room temperature for 10 min, then potassium iodide (2.72 g, 16.4 mmol) was added and the reaction mixture was stirred at room temperature for 96 hours. The reaction mixture was diluted with EtOAc (25 mL) and 1 M aqueous sodium thiosulfate. The solution (25 mL) was added and the resulting mixture was stirred for 15 minutes. The solution was poured into 250 mLErlenmeyer and washed with EtOAc (50 mL) and 1 M aqueous sodium thiosulfate. solution (50mL) and the resulting solution was stirred for another 15 minutes. The organic layer was separated and the aqueous phase was further extracted with EtOAc (3 x 50 mL). The combined organic layers were washed with brine (100 mL), dried over Na2SO4, filtered and concentrated to dryness to afford 4-hydroxy-3,5-diiodobenzaldehyde (2.91 g, 95% yield) as a light yellow solid.
3,5-Diiodo-4-hydroxybenzaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Changer Pharmaceutical Technology Co. Ltd. | 15921595598;15921595598 | qd.yu@pharmachanger.com | China | 469 | 58 |
| Liuyang huarui material technology co., ltd. | 13467605171 | 2580432242@qq.com | China | 184 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
| China Langchem Inc. | 0086-21-58956006 | China | 7798 | 57 | |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400 638 7771 | sales@heowns.com | China | 14412 | 57 |
View Latest Price from 3,5-Diiodo-4-hydroxybenzaldehyde manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-13 | 3,5-DIIODO-4-HYDROXYBENZALDEHYDE
1948-40-9
|
1KG | 98% | 2000 | Shenzhen Nexcon Pharmatechs Ltd. | ||
 |
2026-08-12 | 3,5-DIIODO-4-HYDROXYBENZALDEHYDE
1948-40-9
|
$840.00 | 1KG | 98% | 1-500kg | Baoji Guokang Healthchem Co., Ltd. | |
 |
2025-12-24 | 3,5-DIIODO-4-HYDROXYBENZALDEHYDE
1948-40-9
|
1KG | 99.0% | 1000 tons | Shaanxi Dideu Medichem Co. Ltd |
-
- 3,5-DIIODO-4-HYDROXYBENZALDEHYDE
1948-40-9
- 98%
- Shenzhen Nexcon Pharmatechs Ltd.
-
- 3,5-DIIODO-4-HYDROXYBENZALDEHYDE
1948-40-9
- $840.00
- 98%
- Baoji Guokang Healthchem Co., Ltd.
-
- 3,5-DIIODO-4-HYDROXYBENZALDEHYDE
1948-40-9
- $0.10
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
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