ChemicalBook >> CAS DataBase List >>2,2,2-Trifluoro-3'-(trifluoromethyl)acetophenone

2,2,2-Trifluoro-3'-(trifluoromethyl)acetophenone

CAS No.
721-37-9
Chemical Name:
2,2,2-Trifluoro-3'-(trifluoromethyl)acetophenone
Synonyms
3-Trifluoromethyltrifluoroacetophenone;3-TRIFLUOROMETHYL-A,A,A-TRIFLUOROACETOPHENONE;2,2,2-Trifluoro-(trifluoroMethyl)acetophenone;2,2,2-Trifluoro-3'-(trifluoromethyl)acetophenone;3-(Trifluoromethyl)phenyl(trifluoromethyl) ketone;2,2,2-Trifluoro-3'-(trifluoromethyl)acetophenone97%;2,2,2-TRIFLUORO-1-(3-TRIFLUOROMETHYLPHENYL)ETHANONE;2,2,2-Trifluoro-3'-(trifluoromethyl)acetophenone98%;2,2,2-Trifluoro-3'-(trifluoromethyl)acetophenone 98%;2,2,2-trifluoro-1-[3-(trifluoromethyl)phenyl]-ethylone
CBNumber:
CB5410130
Molecular Formula:
C9H4F6O
Molecular Weight:
242.12
MDL Number:
MFCD00061275
MOL File:
721-37-9.mol
MSDS File:
SDS
Last updated:2026-09-12 18:53:31

2,2,2-Trifluoro-3'-(trifluoromethyl)acetophenone Properties

Melting point 76-77 °C
Boiling point 65-67 °C24 mm Hg(lit.)
Density 1.418 g/mL at 25 °C(lit.)
refractive index n20/D 1.415(lit.)
Flash point 139 °F
storage temp. 2-8°C
form liquid
color Clear, almost colourless (hint of peach)
InChI 1S/C9H4F6O/c10-8(11,12)6-3-1-2-5(4-6)7(16)9(13,14)15/h1-4H
InChIKey MDCHHRZBYSSONX-UHFFFAOYSA-N
SMILES FC(F)(F)C(=O)c1cccc(c1)C(F)(F)F
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Flame (GHS02)Exclamation Mark (GHS07)
GHS02,GHS07
Signal word  Warning
Hazard statements  H226-H315-H319-H335
Precautionary statements  P210-P233-P240-P241-P303+P361+P353-P305+P351+P338
target organs Respiratory system
PPE Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
RIDADR  UN 1224 3/PG 3
WGK Germany  3
Hazard Note  Irritant/Lachrymator
HazardClass  3.2
PackingGroup  III
HS Code  2914790090
Storage Class 3 - Flammable liquids
Hazard Classifications Eye Irrit. 2
Flam. Liq. 3
Skin Irrit. 2
STOT SE 3

2,2,2-Trifluoro-3'-(trifluoromethyl)acetophenone price More Price(30)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 370630 2,2,2-Trifluoro-3′-(trifluoromethyl)acetophenone 98% 721-37-9 5g $152 2026-04-30 Buy
Biosynth AAA72137 2,2,2-Trifluoro-3'-(trifluoromethyl)acetophenone 721-37-9 10g $375 2026-06-04 Buy
Apolloscientific PC4349 2,2,2-Trifluoro-3'-(trifluoromethyl)acetophenone 97% 721-37-9 1g $25 2026-06-04 Buy
Apolloscientific PC4349 2,2,2-Trifluoro-3'-(trifluoromethyl)acetophenone 97% 721-37-9 5g $86 2026-06-04 Buy
Apolloscientific PC4349 2,2,2-Trifluoro-3'-(trifluoromethyl)acetophenone 97% 721-37-9 25g $270 2026-06-04 Buy
Product number Packaging Price Buy
370630 5g $152 Buy
AAA72137 10g $375 Buy
PC4349 1g $25 Buy
PC4349 5g $86 Buy
PC4349 25g $270 Buy

2,2,2-Trifluoro-3'-(trifluoromethyl)acetophenone Chemical Properties,Uses,Production

Uses

Preparation of 2,2,2-trifluoro-3′-(trifluoromethyl)acetophenone (3-trifluoromethyltrifluoroacetophenone) by Grignard synthesis using m-trifluoromethylbromo-benzene and trifluoroacetic acid has been reported.

General Description

Preparation of 2,2,2-trifluoro-3′-(trifluoromethyl)acetophenone (3-trifluoromethyltrifluoroacetophenone) by Grignard synthesis using m-trifluoromethylbromo-benzene and trifluoroacetic acid has been reported.

2,2,2-Trifluoro-3'-(trifluoromethyl)acetophenone Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 84)Suppliers
Supplier Tel Email Country ProdList Advantage
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Shanghai AmasPharm Co., Ltd. 021-54540637 18621091017 sales@amaspharm.com China 787 62
ZhengZhou HuaWen Chemical Co.Ltd 0370-2785118 17550508557 675141927@qq.com China 3201 55
Tianjin Jinyuda Chemical Co., Ltd. 022-58013646 13011382049 sales@jinyudachem.com China 1976 55
Shijiazhuang Lickon PharmaTech Co., Ltd. 031185291771 13832391721 yaofeng2005@163.com China 947 58
Cochemical Ltd. 029-86115547 17791676824 sales@cochemical.com China 3014 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Cool Pharm, Ltd 021-60455363 18019463053 sales@coolpharm.com China 8455 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
3-Trifluoromethyltrifluoroacetophenone 3-Trifluoromethyl-alpha,alpha,alpha-trifluoroacetophenone 2,2,2-Trifluoro-3'-(trifluoromethyl)acetophenone 98% 2,2,2-Trifluoro-3'-(trifluoromethyl)acetophenone98% 2,2,2-TRIFLUORO-1-(3-TRIFLUOROMETHYLPHENYL)ETHANONE ALPHA,ALPHA,ALPHA-TRIFLUORO-3-(TRIFLUOROMETHYL)ACETOPHENONE 3-TRIFLUOROMETHYL-A,A,A-TRIFLUOROACETOPHENONE 3-(Trifluoromethyl)phenyl(trifluoromethyl) ketone 3-(Trifluoroacetyl)benzotrifluoride, 1-[(Trifluoromethyl)phenyl]-2,2,2-trifluoroethan-1-one 3-(Trifluoroacetyl)benzotrifluoride, 1-[3-(Trifluoromethyl)phenyl]-2,2,2-trifluoroethan-1-one 2,2,2-Trifluoro-3'-(trifluoromethyl)acetophenone97% Ethanone, 2,2,2-trifluoro-1-[3-(trifluoromethyl)phenyl]- 2,2,2-Trifluoro-(trifluoroMethyl)acetophenone 2,2,2-Trifluoro-3′-(trifluoromethyl)acetophenone, CAS 721-37-9 2,2,2-trifluoro-1-[3-(trifluoromethyl)phenyl]-ethylone 2,2,2-Trifluoro-3'-(trifluoromethyl)acetophenone 721-37-9 CF3C6H4COCF3 Ketones Organic Building Blocks Building Blocks C9 Carbonyl Compounds C9 Carbonyl Compounds Ketones