6-methyl-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide
- CAS No.
- 352554-02-0
- Chemical Name:
- 6-methyl-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide
- Synonyms
- SIRT1-IN-1;SIRT1-IN-1, 10 mM in DMSO;6-methyl-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide;1H-Carbazole-1-carboxamide, 2,3,4,9-tetrahydro-6-methyl-;inhibit,Cytomegalovirus,CMV,antiviral,indole,Inhibitor,Sirtuin,SIRT1IN1,SIRT1 IN 1
- CBNumber:
- CB54253236
- Molecular Formula:
- C14H16N2O
- Molecular Weight:
- 228.29
- MDL Number:
- MFCD00846511
- MOL File:
- 352554-02-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H319 |
| Precautionary statements | P264-P270-P280-P301+P312+P330-P305+P351+P338-P337+P313-P501 |
6-methyl-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | CPA55402 | SIRT1-IN-1 | 352554-02-0 | 1mg | $250 | 2026-06-04 | Buy |
| Biosynth | CPA55402 | SIRT1-IN-1 | 352554-02-0 | 5mg | $611.7 | 2026-06-04 | Buy |
| Biosynth | CPA55402 | SIRT1-IN-1 | 352554-02-0 | 10mg | $978.7 | 2026-06-04 | Buy |
| Biosynth | CPA55402 | SIRT1-IN-1 | 352554-02-0 | 25mg | $1835.25 | 2026-06-04 | Buy |
| Biosynth | CPA55402 | SIRT1-IN-1 | 352554-02-0 | 50mg | $2936 | 2026-06-04 | Buy |
6-methyl-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide Chemical Properties, Uses, Production
Uses
SIRT1-IN-1 is a selective SIRT1 inhibitor with an IC50 of 0.205 μM. SIRT1-IN-1 inhibits SIRT2 with an IC50 of 11.5 μM[1]. SIRT1-IN-1, a indole, is a cytomegalovirus (CMV) inhibitors and has antiviral activity[2].
IC 50
SIRT1: 0.205 μM (IC50); SIRT2: 11.5 μM (IC50); SIRT3: >100 μM (IC50)
References
[1] Andrew D Napper, et al. Discovery of Indoles as Potent and Selective Inhibitors of the Deacetylase SIRT1. J Med Chem. 2005 Dec 15;48(25):8045-54. DOI:10.1021/jm050522v
[2] Thomas Shenk, et al. Sirtuin Modulators as Inhibitors of Cytomegalovirus. US20160296523A1.
6-methyl-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide Preparation Products And Raw materials
Raw materials
Preparation Products
6-methyl-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shanghai SuperLan Chemcial Technique Centre | 0-2022843681 15618226720 | chaolaichem@foxmail.com | China | 9996 | 58 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 17801761073 18101056239 | 3193328036@qq.com | China | 28150 | 68 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| Jinan Jiuli Biotechnology Co. , Ltd. | 15865264761 | 486064515@qq.com | China | 5000 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5985 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | cindy.huang@synzest.com | China | 11975 | 58 |
| RD International Technology Co., Limited | 18024082417 | market@ubiochem.com | China | 9831 | 58 |
